US Tech Solutions
Overview
Duration: 12+ months contract Job Description: We are searching for a highly motivated Scientist to join our
Analytical Development team
at client Bioresearch Center in Worcester, MA. Our team is
responsible for the development, qualification, and execution of analytical methods to provide product and process understanding for biological entities
from discovery through commercial stages. As a Scientist, you will be a part of the
Analytical Characterization Group (ACG)
within the Analytical Development Department. ACG focuses on
providing routine, investigative, and in-depth characterization analyses
of client’s biologics to
support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC-MS), spectroscopy
and various other biophysical assays. The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department.
Responsibilities
Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS ) of client’s biologics to provide
sequence verification and post-translational modification profiles .
Independently
perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA
Perform biophysical methods (e.g., DSC ) of client’s biologics to support characterization studies.
Design and execute experiments for method development and/or investigations.
Support
process development by performing raw material analysis
using
vibrational spectroscopy and executing metabolomics
experiments using mass spectrometry.
Generate and communicate precise, reliable, and reproducible data in a timely manner.
Organize and document experiments and results in an electronic laboratory notebook.
Draft protocols, method development reports, and technical characterization reports.
Maintain lab equipment.
Experience
Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting.
Hands-on experience with protein mass spectrometry, liquid chromatography, capillary electrophoresis and protein biophysical characterization.
Knowledge of HPLC or AKTA instrumentation
Fundamental understanding of protein structure, post-translational modifications, and analytical methods used for protein characterization.
Working knowledge of bioinformatics tools to process and analyze mass spectrometry data is highly desirable.
Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.
Proficient with Windows 10 and Microsoft Office (Outlook, Excel, Word, and PowerPoint).
Excellent written communication, oral communication, organization, and multitasking skills.
Hardworking and motivated to drive both efficiency and quality.
Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials.
Skills
HPLC/UPLC, AKTA, LC-MS, protein, & protein characterization, mass spectrometry.
Education
Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting
About US Tech Solutions US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
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Duration: 12+ months contract Job Description: We are searching for a highly motivated Scientist to join our
Analytical Development team
at client Bioresearch Center in Worcester, MA. Our team is
responsible for the development, qualification, and execution of analytical methods to provide product and process understanding for biological entities
from discovery through commercial stages. As a Scientist, you will be a part of the
Analytical Characterization Group (ACG)
within the Analytical Development Department. ACG focuses on
providing routine, investigative, and in-depth characterization analyses
of client’s biologics to
support product and process development for early-phase, late-phase, and commercial programs using liquid chromatography mass spectrometry (LC-MS), spectroscopy
and various other biophysical assays. The successful candidate will contribute to the development and performance of analytical assays and will contribute to the continuous improvement and innovation within ACG and the Analytical Development Department.
Responsibilities
Perform mass spectrometry analyses (i.e., intact/reduced mass analysis by LC-MS and peptide mapping by LC-MS ) of client’s biologics to provide
sequence verification and post-translational modification profiles .
Independently
perform separation methods (e.g., fractionation & analysis of variants) using HPLC and AKTA
Perform biophysical methods (e.g., DSC ) of client’s biologics to support characterization studies.
Design and execute experiments for method development and/or investigations.
Support
process development by performing raw material analysis
using
vibrational spectroscopy and executing metabolomics
experiments using mass spectrometry.
Generate and communicate precise, reliable, and reproducible data in a timely manner.
Organize and document experiments and results in an electronic laboratory notebook.
Draft protocols, method development reports, and technical characterization reports.
Maintain lab equipment.
Experience
Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting.
Hands-on experience with protein mass spectrometry, liquid chromatography, capillary electrophoresis and protein biophysical characterization.
Knowledge of HPLC or AKTA instrumentation
Fundamental understanding of protein structure, post-translational modifications, and analytical methods used for protein characterization.
Working knowledge of bioinformatics tools to process and analyze mass spectrometry data is highly desirable.
Knowledge of vibrational spectroscopy (e.g., IR, NIR and Raman) and multivariate analysis is desirable.
Proficient with Windows 10 and Microsoft Office (Outlook, Excel, Word, and PowerPoint).
Excellent written communication, oral communication, organization, and multitasking skills.
Hardworking and motivated to drive both efficiency and quality.
Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials.
Skills
HPLC/UPLC, AKTA, LC-MS, protein, & protein characterization, mass spectrometry.
Education
Bachelors or Masters in chemistry, biology, biochemistry or related technical discipline with typically 5+ (BS) or 2+ (MS) years of relevant experience in biotech/pharmaceutical industry setting
About US Tech Solutions US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
#J-18808-Ljbffr