SRA/ Associate Scientist- Protein Purification

Direct message the job poster from Celltheon Corporation Join Celltheon and help develop the next generation of biologics and ADCs Celltheon is seeking a motivated, detail-oriented scientist

to join our

Protein Purification & Analytics

team. In this hands-on laboratory role, you will contribute to the

development, optimization, and scale-up

of purification processes for recombinant proteins and conjugated modalities — including monoclonal antibodies, bispecifics, Fc-fusions, difficult-to-express proteins, and

antibody-drug conjugates (ADCs) . You will work closely with experienced scientists across molecular biology, cell culture, and manufacturing to support projects from

early-stage development through GMP readiness . Key Responsibilities Assist in developing and optimizing 1–3 column purification workflows (SEC, ProA, CEX, AEX, HIC, IMAC, mixed modes) for mammalian-expressed proteins- mabs, Fc-fusion, Bispecific, ScFv etc Support purification and characterization of ADCs and conjugated proteins in collaboration with our bioconjugation team. Perform analytical assays such as Protein A HPLC for titer, SEC-HPLC, CEX-HPLC, RP-HPLC, SDS-PAGE, and ADC-specific methods (training provided). Operate and maintain FPLC and analytical HPLC systems, including cleaning and changeovers. Have experience with automation systems- Hamilton for HTP purification Accurately document all work in

ELNs , batch records, and SOPs. Work collaboratively with cross-functional teams to troubleshoot and solve technical challenges, method development experience. Experience with generating low endotoxin protein for animal studies This is fast paced purification environment and the ideal candidate should be up to the challenge of purifying >100 mabs/ week with supporting analytical data. What We’re Looking For Masters degree in Biotechnology, Biochemistry, Bioprocessing, or related field

plus 3-4 years industry experience. Hands-on laboratory experience with

protein purification

(FPLC experience strongly preferred). Familiarity with analytical HPLC and chromatography methods a plus. Experience in ADC purification/characterization is desirable. Strong attention to detail, organizational skills, maintain purification lab inventory and

ELN proficiency . Team player with excellent communication skills. Clients timeline are important- ability to manage workflows and deliver on target is a must About Celltheon Celltheon Corporation is a biotechnology company in the San Francisco Bay Area

specializing in advanced expression technologies and ADC development. Our proprietary platforms —

OmniCHO™

for transient expression,

Goldilocks™ Transposase

for stable cell line development, and

SUPER CELL™ CHOK1

for difficult-to-express proteins — deliver

high titers, exceptional quality, and rapid timelines . We provide end-to-end solutions from molecular design through manufacturing-scale processes, including full

bioconjugation services for ADCs . At Celltheon, you’ll work in a

collaborative, fast-paced environment

where creativity is encouraged, challenges are welcomed, and your contributions make an immediate impact.

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