e184
e184 is a biotechnology research company advancing in vitro gametogenesis to transform reproductive medicine. We're developing integrated platforms that combine cellular reprogramming, machine learning-guided optimization, multi-omics analysis, and automated experimental workflows to enable gamete development for individuals facing reproductive challenges. We're assembling interdisciplinary teams across cell and molecular engineering, synthetic biology, epigenetic editing, bioinformatics and computational biology to tackle one of biology's most impactful problems - returning the fundamental right to procreate.
Role overview Most research assistant positions involve executing protocols someone else designed, in systems someone else built, following SOPs someone else wrote.
This role is not that.
You'll work directly alongside our CSO/co-founder and Science Team Leads helping build something from scratch. You'll have input on procurement decisions, equipment choices, lab layout, and operational systems. When we design our new facility, you'll be part of those conversations.
You'll see how a biotech startup actually works - the business development, the strategic decisions about what experiments to prioritize and why. This exposure is nearly impossible to get in academic labs or established companies.
You'll wear multiple hats and develop a broad skill set. One day you're troubleshooting iPSC culture protocols, the next you're evaluating vendors for cell culture reagents, and the following week you're helping write SOPs for our quality management system. This breadth accelerates your professional development in ways that narrowly-focused positions cannot.
You'll contribute to cutting-edge science in stem cell biology, working on technologies that could fundamentally change reproductive medicine. Your work will directly enable experiments that move us toward clinical applications.
This isn't a 9-to-5 job. It's startup life - sometimes chaotic, always demanding, occasionally uncertain. But if you're at a stage in your career where learning and growth matter, this is a rare opportunity.
Primary responsibilities Cell culture operations (50-60% of your time)
Perform primary cell derivations and maintain mammalian cell cultures
Conduct iPSC reprogramming, culture, characterization, and banking
Develop and validate reporter cell lines using knock-in techniques
Maintain detailed experimental records and documentation
Troubleshoot culture conditions and optimize protocols
Lab operations and management (40-50% of your time)
Assist with vendor evaluation and procurement of lab supplies and equipment
Help establish and document standard operating procedures
Maintain lab organization, inventory management, and quality standards
Contribute to lab setup and design decisions for our upcoming facility expansion
Support regulatory compliance and documentation requirements
What this actually looks like day-to-day: Expect extended periods of hands-on lab work. Cell culture doesn't accommodate a traditional schedule - cells need attention when they need it, including weekends. You'll need to be adaptable when priorities shift (they will), detail-oriented when documenting experiments (always), and comfortable working independently while also communicating proactively about challenges and progress.
Required qualifications
Bachelor's degree in Biology, Biotechnology, Cell or Molecular Biology, or related field
Hands-on laboratory experience with mammalian cell culture
Strong organizational skills and attention to detail
Ability to work independently with minimal supervision
Comfortable with weekend responsibilities for cell culture maintenance
Physical ability to handle extended periods of laboratory work
Genuine excitement about startup environment and mission-driven science
Preferred qualifications
1-3 years of research experience (academic or industry)
iPSC culture and characterization experience
CRISPR/Cas9 experience (or strong desire to learn)
Previous startup or fast-paced environment experience
Who we're looking for
You're someone who gets energized by building things, not just maintaining them
You're comfortable with ambiguity and can make good decisions without perfect information
You ask questions, suggest improvements, and take ownership of problems
You're self-aware about what you don't know and proactive about learning
You value being part of something meaningful
You're at a career stage where growth opportunities matter the most
What we offer
Competitive compensation, equity participation, and comprehensive benefits
Direct mentorship from CSO and Science Team Leads
Early employee status and ability to grow with the company
Broad exposure across scientific, operational, and business functions
Real input on decisions that shape the company
Experience building a biotech company from the ground up - invaluable if you have entrepreneurial interests
More autonomy, more diverse responsibilities, and more direct impact than you'd have almost anywhere else at this career stage
Work that directly contributes to addressing infertility challenges
Disclaimer The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of e184.
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Role overview Most research assistant positions involve executing protocols someone else designed, in systems someone else built, following SOPs someone else wrote.
This role is not that.
You'll work directly alongside our CSO/co-founder and Science Team Leads helping build something from scratch. You'll have input on procurement decisions, equipment choices, lab layout, and operational systems. When we design our new facility, you'll be part of those conversations.
You'll see how a biotech startup actually works - the business development, the strategic decisions about what experiments to prioritize and why. This exposure is nearly impossible to get in academic labs or established companies.
You'll wear multiple hats and develop a broad skill set. One day you're troubleshooting iPSC culture protocols, the next you're evaluating vendors for cell culture reagents, and the following week you're helping write SOPs for our quality management system. This breadth accelerates your professional development in ways that narrowly-focused positions cannot.
You'll contribute to cutting-edge science in stem cell biology, working on technologies that could fundamentally change reproductive medicine. Your work will directly enable experiments that move us toward clinical applications.
This isn't a 9-to-5 job. It's startup life - sometimes chaotic, always demanding, occasionally uncertain. But if you're at a stage in your career where learning and growth matter, this is a rare opportunity.
Primary responsibilities Cell culture operations (50-60% of your time)
Perform primary cell derivations and maintain mammalian cell cultures
Conduct iPSC reprogramming, culture, characterization, and banking
Develop and validate reporter cell lines using knock-in techniques
Maintain detailed experimental records and documentation
Troubleshoot culture conditions and optimize protocols
Lab operations and management (40-50% of your time)
Assist with vendor evaluation and procurement of lab supplies and equipment
Help establish and document standard operating procedures
Maintain lab organization, inventory management, and quality standards
Contribute to lab setup and design decisions for our upcoming facility expansion
Support regulatory compliance and documentation requirements
What this actually looks like day-to-day: Expect extended periods of hands-on lab work. Cell culture doesn't accommodate a traditional schedule - cells need attention when they need it, including weekends. You'll need to be adaptable when priorities shift (they will), detail-oriented when documenting experiments (always), and comfortable working independently while also communicating proactively about challenges and progress.
Required qualifications
Bachelor's degree in Biology, Biotechnology, Cell or Molecular Biology, or related field
Hands-on laboratory experience with mammalian cell culture
Strong organizational skills and attention to detail
Ability to work independently with minimal supervision
Comfortable with weekend responsibilities for cell culture maintenance
Physical ability to handle extended periods of laboratory work
Genuine excitement about startup environment and mission-driven science
Preferred qualifications
1-3 years of research experience (academic or industry)
iPSC culture and characterization experience
CRISPR/Cas9 experience (or strong desire to learn)
Previous startup or fast-paced environment experience
Who we're looking for
You're someone who gets energized by building things, not just maintaining them
You're comfortable with ambiguity and can make good decisions without perfect information
You ask questions, suggest improvements, and take ownership of problems
You're self-aware about what you don't know and proactive about learning
You value being part of something meaningful
You're at a career stage where growth opportunities matter the most
What we offer
Competitive compensation, equity participation, and comprehensive benefits
Direct mentorship from CSO and Science Team Leads
Early employee status and ability to grow with the company
Broad exposure across scientific, operational, and business functions
Real input on decisions that shape the company
Experience building a biotech company from the ground up - invaluable if you have entrepreneurial interests
More autonomy, more diverse responsibilities, and more direct impact than you'd have almost anywhere else at this career stage
Work that directly contributes to addressing infertility challenges
Disclaimer The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties, responsibilities, and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company, and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of e184.
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