University of Miami
Job Title
Full Time Transgenic and Gene Targeting – Scientist
Location UHealth campus, Miami, FL
Overview The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Transgenic and Gene Targeting – Scientist to work at the UHealth campus in Miami, Fl.
Core Job Summary The Scientist, SOM supports the University’s research goals and objectives by engaging in complex experiments and investigations in a range of areas, depending on specialty and interests. Moreover, an employee in this position contributes to the scientific community and promotes the University’s reputation as a leader in the field.
Core Job Functions Oversees research employees, students, and other relevant staff. Authors scientific publications, technical and agency reports, and patent applications. Assists in the development of training materials for research staff. Plans experiment and records and analyzes findings. Prepares research proposals and funding applications. Ensures that all activities are in compliance with applicable quality and regulatory standards. Maintains current knowledge of relevant scientific and technical developments. Presents ongoing work and findings to colleagues at academic conferences. Adheres to University and unit-level policies and procedures and safeguards University assets.
This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.
Core Qualifications
Education: Ph.D., M.D. or other doctoral level degree in relevant field
Experience: Minimum 10 years of relevant experience
Knowledge, Skills and Attitudes:
Skill in collecting, organizing, and analyzing data.
Ability to recognize, analyze, and solve a variety of problems.
Ability to exercise sound judgment in making critical decisions.
Department Specific Functions The Sylvester Comprehensive Cancer Center is currently seeking a Transgenic and Gene Targeting – Scientist who will join the Cancer Modeling Shared Resource. This translational Facility provides qualified, cost effective and state-of-the-art services to foster cancer research advancements and accelerate the discovery of tailored antitumor therapies. We are seeking a dynamic individual who would like to participate in the creation and development of new service lines in a busy and fast-paced environment, mainly focused on the generation of state-of-the-art services necessary to generate novel mouse models of cancer using advanced techniques and technologies to produce and manipulate customized genetically engineered rodents. This person will directly assist the Director in running and implementing these new genetic engineering services to support researchers in the field of functional genomics and disease modeling. The successful candidate will also participate in the planning and implementation of genome editing and transgenic projects including being responsible for the experimental design, procurement and validation of the services provided and models produced under the direction of Dr. Bilbao.
Specific responsibilities of the position include and are not limited to:
Ensure the implementation of transgenic and genetic engineering services.
Use CRISPR/Cas9 targeting to produce gene knockouts, conditional knockouts, single-point mutations, and insertions and gene fusions, also simultaneously mutating multiple genes in a single experiment.
Generate transgenic mice by injecting plasmid or bacterial artificial chromosome DNA constructs into inbred and outbred mouse strains.
Generate knockout (KO), conditional knockout (CKO), and knock-in (KI) mice using traditional ES cell targeting including C57BL6 ESCs; ES cell, tetraploid and iPS cell microinjection; rederivation; embryo and sperm cryopreservation; in vitro fertilization; tail biopsy and genotyping.
Independently conduct research projects based on reviews of scientific literature and recent advances in related fields while contributing original/novel ideas of major methodological significance, designing key experiments, and developing new techniques.
Advise, support, and train relevant personnel on technical procedures, techniques, and reagents needed to generate required SOPs to support functional genomics services.
Manage and coordinate activities of assigned projects with responsibility for results in terms of costs, methods, and resources.
Work with the director and the team to develop, adapt and implement new services and state-of-the-art technologies while maintaining up-to-date knowledge of the genetic engineering and in vivo transgenesis field.
Adhere to University and unit-level policies and procedures; safeguard University assets; participate in University/outside educational training as required.
Perform other duties as requested.
Department Specific Qualifications
Education: Ph.D., M.D. or other doctoral level degree in molecular biological, veterinary or biomedical sciences.
Experience: Minimum 10 years of relevant experience in the field of genetic engineering and/or animal models. Experience in service provision and/or management in a research core facility is preferred.
Knowledge, Skills and Attitudes:
Proactively helpful in all aspects of the job, whether it involves communication, training, reporting, or project/team management.
Mechanical ability and dexterity when performing the different lab-related techniques.
Skill in completing assignments accurately and with attention to detail.
Ability to understand and follow specific instructions and procedures.
Excellent computer skills and proficiency with general and specialized data analysis software and databases.
Knowledge of the use and maintenance of laboratory facilities and/or specialized equipment.
Knowledge of molecular biology procedures, general laboratory operations and/or procedures, as well as knowledge of supplies, equipment, and/or services ordering.
Self-motivated individual with a strong desire to learn.
Exceptional critical thinking and strong analytical, problem solving, and troubleshooting skills.
Excellent interpersonal and communication skills. Expected to interact with a variety of staff (facility team, users, and other related facilities) in a professional, polite, and positive attitude.
Ability to train and manage people.
Excellent English (both verbal and written) required.
Ability to shift focus between multiple projects, organize and prioritize work under pressure while meeting deadlines.
Excellent time-management skills.
Ability to work evenings, nights, and weekends as necessary.
Commitment to the University’s core values.
Ability to work independently and in a collaborative environment.
Ability to work in an interdisciplinary team under the direction of the Director of the Facility.
Ability to perform other duties as assigned.
Benefits The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.
Equal Opportunity Employer The University of Miami is an Equal Opportunity Employer – Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.
Job Information Job Status: Full time Employee Type: Staff Pay Grade: A14
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Location UHealth campus, Miami, FL
Overview The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Transgenic and Gene Targeting – Scientist to work at the UHealth campus in Miami, Fl.
Core Job Summary The Scientist, SOM supports the University’s research goals and objectives by engaging in complex experiments and investigations in a range of areas, depending on specialty and interests. Moreover, an employee in this position contributes to the scientific community and promotes the University’s reputation as a leader in the field.
Core Job Functions Oversees research employees, students, and other relevant staff. Authors scientific publications, technical and agency reports, and patent applications. Assists in the development of training materials for research staff. Plans experiment and records and analyzes findings. Prepares research proposals and funding applications. Ensures that all activities are in compliance with applicable quality and regulatory standards. Maintains current knowledge of relevant scientific and technical developments. Presents ongoing work and findings to colleagues at academic conferences. Adheres to University and unit-level policies and procedures and safeguards University assets.
This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.
Core Qualifications
Education: Ph.D., M.D. or other doctoral level degree in relevant field
Experience: Minimum 10 years of relevant experience
Knowledge, Skills and Attitudes:
Skill in collecting, organizing, and analyzing data.
Ability to recognize, analyze, and solve a variety of problems.
Ability to exercise sound judgment in making critical decisions.
Department Specific Functions The Sylvester Comprehensive Cancer Center is currently seeking a Transgenic and Gene Targeting – Scientist who will join the Cancer Modeling Shared Resource. This translational Facility provides qualified, cost effective and state-of-the-art services to foster cancer research advancements and accelerate the discovery of tailored antitumor therapies. We are seeking a dynamic individual who would like to participate in the creation and development of new service lines in a busy and fast-paced environment, mainly focused on the generation of state-of-the-art services necessary to generate novel mouse models of cancer using advanced techniques and technologies to produce and manipulate customized genetically engineered rodents. This person will directly assist the Director in running and implementing these new genetic engineering services to support researchers in the field of functional genomics and disease modeling. The successful candidate will also participate in the planning and implementation of genome editing and transgenic projects including being responsible for the experimental design, procurement and validation of the services provided and models produced under the direction of Dr. Bilbao.
Specific responsibilities of the position include and are not limited to:
Ensure the implementation of transgenic and genetic engineering services.
Use CRISPR/Cas9 targeting to produce gene knockouts, conditional knockouts, single-point mutations, and insertions and gene fusions, also simultaneously mutating multiple genes in a single experiment.
Generate transgenic mice by injecting plasmid or bacterial artificial chromosome DNA constructs into inbred and outbred mouse strains.
Generate knockout (KO), conditional knockout (CKO), and knock-in (KI) mice using traditional ES cell targeting including C57BL6 ESCs; ES cell, tetraploid and iPS cell microinjection; rederivation; embryo and sperm cryopreservation; in vitro fertilization; tail biopsy and genotyping.
Independently conduct research projects based on reviews of scientific literature and recent advances in related fields while contributing original/novel ideas of major methodological significance, designing key experiments, and developing new techniques.
Advise, support, and train relevant personnel on technical procedures, techniques, and reagents needed to generate required SOPs to support functional genomics services.
Manage and coordinate activities of assigned projects with responsibility for results in terms of costs, methods, and resources.
Work with the director and the team to develop, adapt and implement new services and state-of-the-art technologies while maintaining up-to-date knowledge of the genetic engineering and in vivo transgenesis field.
Adhere to University and unit-level policies and procedures; safeguard University assets; participate in University/outside educational training as required.
Perform other duties as requested.
Department Specific Qualifications
Education: Ph.D., M.D. or other doctoral level degree in molecular biological, veterinary or biomedical sciences.
Experience: Minimum 10 years of relevant experience in the field of genetic engineering and/or animal models. Experience in service provision and/or management in a research core facility is preferred.
Knowledge, Skills and Attitudes:
Proactively helpful in all aspects of the job, whether it involves communication, training, reporting, or project/team management.
Mechanical ability and dexterity when performing the different lab-related techniques.
Skill in completing assignments accurately and with attention to detail.
Ability to understand and follow specific instructions and procedures.
Excellent computer skills and proficiency with general and specialized data analysis software and databases.
Knowledge of the use and maintenance of laboratory facilities and/or specialized equipment.
Knowledge of molecular biology procedures, general laboratory operations and/or procedures, as well as knowledge of supplies, equipment, and/or services ordering.
Self-motivated individual with a strong desire to learn.
Exceptional critical thinking and strong analytical, problem solving, and troubleshooting skills.
Excellent interpersonal and communication skills. Expected to interact with a variety of staff (facility team, users, and other related facilities) in a professional, polite, and positive attitude.
Ability to train and manage people.
Excellent English (both verbal and written) required.
Ability to shift focus between multiple projects, organize and prioritize work under pressure while meeting deadlines.
Excellent time-management skills.
Ability to work evenings, nights, and weekends as necessary.
Commitment to the University’s core values.
Ability to work independently and in a collaborative environment.
Ability to work in an interdisciplinary team under the direction of the Director of the Facility.
Ability to perform other duties as assigned.
Benefits The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.
Equal Opportunity Employer The University of Miami is an Equal Opportunity Employer – Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.
Job Information Job Status: Full time Employee Type: Staff Pay Grade: A14
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