Pattern Biosciences
Biomarker Scientist, Cancer Gene Therapy
Pattern Biosciences, South San Francisco, California, us, 94083
Biomarker Scientist, Cancer Gene Therapy
Join to apply for the
Biomarker Scientist, Cancer Gene Therapy
role at
Pattern Biosciences Biomarker Scientist, Cancer Gene Therapy
Join to apply for the
Biomarker Scientist, Cancer Gene Therapy
role at
Pattern Biosciences Get AI-powered advice on this job and more exclusive features. You will lead the planning and execution of biomarker strategy and drive biomarker assay development for preclinical and clinical oncology studies using gene therapy modality. In this role, you will collaborate with cross-functional teams and external partners to drive clinical biomarker innovation for cancer gene therapy programs. This is an ideal position for a highly motivated individual who has strong wet-lab and data analysis skills, and thrives in a cross-disciplinary and collaborative environment.
Primary Responsibilities
Establish translatable biomarkers for preclinical and clinical development, including biomarkers for patient selection, drug response monitoring, pharmacodynamics and mechanism of action Design and validate biomarker assays, developing SOPs for robust and reproducible biomarker quantification using patient-derived specimens. Contribute to biomarker strategy in clinical trials Work closely with the biospecimen team to optimize, standardize and document pre-analytical biospecimen handling and processing conditions to support the transition of biomarker assays into clinical trials Oversee and manage relationships with CROs and vendors for outsourced clinical biomarker assay development, validation, and regulatory compliance Analyze biomarker data to derive insights into patient response, pharmacodynamics, and mechanisms of action Collaborate with regulatory teams to ensure biomarker strategies align with clinical trial and regulatory submission requirements
Required Skills & Qualifications
PhD and/or MD with 3+ years of industry experience in oncology disease or cell/gene therapy (CGT) Excellent understanding of drug development and regulatory processes Extensive hands-on experience developing biomarker assay protocols and analyzing patient specimens using techniques such as IHC/IF, ISH, ELISA and ELISPOT Experience leading biomarker assay outsourcing with external vendors/CROs Excellent written and communication skills Thrives in a fast-paced, high-growth environment with a track record of delivering results on time and within budget Proven ability to work independently and collaboratively in a team environment
At Pattern Bio, we design biological circuits at the intersection of synthetic biology and AI for cell-specific targeting of cancer tissue. By integrating data-driven design into every step—from DNA constructs to AAV-based delivery systems—we are building precise, rationally engineered, curative therapies. Our cohesive and driven team in South San Francisco is dedicated to curing cancer and saving lives. Seniority level
Seniority level Not Applicable Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at Pattern Biosciences by 2x Get notified about new Scientist jobs in
South San Francisco, CA . Foster City, CA $135,000.00-$185,000.00 1 week ago Hayward, CA $125,000.00-$150,000.00 2 weeks ago Fremont, CA $110,000.00-$115,000.00 3 weeks ago South San Francisco, CA $57,574.40-$110,635.20 3 days ago South San Francisco, CA $100,000.00-$200,000.00 2 days ago Scientist I/II, Biologics Cell Line Development
Alameda, CA $86,700.00-$173,300.00 4 days ago Hayward, CA $125,000.00-$145,000.00 1 week ago Senior Research Associate / Associate Scientist - Polymer
Assoc Scientist R&D, RNA Assay Development
Alameda, CA $86,700.00-$173,300.00 1 week ago Menlo Park, CA $100,000.00-$150,000.00 3 weeks ago Principal Clinical Research Scientist # 4365
Development Associate II to Associate Scientist
Scientist 1/2/Senior Scientist, Analytical Development
Scientist/Senior Scientist, Analytical Chemistry
San Francisco County, CA $75.00-$85.00 3 weeks ago Clinical Variant Interpretation Scientist (Remote)
San Francisco, CA $100,000.00-$150,000.00 1 month ago Research Scientist - Computational Chemistry
Oakland, CA $150,000.00-$185,000.00 1 month ago Scientist/Senior Scientist, Analytical Chemistry
San Mateo County, CA $75.00-$85.00 3 weeks ago Newark, CA $150,000.00-$175,000.00 2 weeks ago San Francisco, CA $145,000.00-$175,000.00 1 day ago Senior Scientist I, Cell/Molecular Biology - Cell Line Development
South San Francisco, CA $94,000.00-$178,500.00 2 weeks ago San Francisco, CA $166,000.00-$244,000.00 2 days ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr
Join to apply for the
Biomarker Scientist, Cancer Gene Therapy
role at
Pattern Biosciences Biomarker Scientist, Cancer Gene Therapy
Join to apply for the
Biomarker Scientist, Cancer Gene Therapy
role at
Pattern Biosciences Get AI-powered advice on this job and more exclusive features. You will lead the planning and execution of biomarker strategy and drive biomarker assay development for preclinical and clinical oncology studies using gene therapy modality. In this role, you will collaborate with cross-functional teams and external partners to drive clinical biomarker innovation for cancer gene therapy programs. This is an ideal position for a highly motivated individual who has strong wet-lab and data analysis skills, and thrives in a cross-disciplinary and collaborative environment.
Primary Responsibilities
Establish translatable biomarkers for preclinical and clinical development, including biomarkers for patient selection, drug response monitoring, pharmacodynamics and mechanism of action Design and validate biomarker assays, developing SOPs for robust and reproducible biomarker quantification using patient-derived specimens. Contribute to biomarker strategy in clinical trials Work closely with the biospecimen team to optimize, standardize and document pre-analytical biospecimen handling and processing conditions to support the transition of biomarker assays into clinical trials Oversee and manage relationships with CROs and vendors for outsourced clinical biomarker assay development, validation, and regulatory compliance Analyze biomarker data to derive insights into patient response, pharmacodynamics, and mechanisms of action Collaborate with regulatory teams to ensure biomarker strategies align with clinical trial and regulatory submission requirements
Required Skills & Qualifications
PhD and/or MD with 3+ years of industry experience in oncology disease or cell/gene therapy (CGT) Excellent understanding of drug development and regulatory processes Extensive hands-on experience developing biomarker assay protocols and analyzing patient specimens using techniques such as IHC/IF, ISH, ELISA and ELISPOT Experience leading biomarker assay outsourcing with external vendors/CROs Excellent written and communication skills Thrives in a fast-paced, high-growth environment with a track record of delivering results on time and within budget Proven ability to work independently and collaboratively in a team environment
At Pattern Bio, we design biological circuits at the intersection of synthetic biology and AI for cell-specific targeting of cancer tissue. By integrating data-driven design into every step—from DNA constructs to AAV-based delivery systems—we are building precise, rationally engineered, curative therapies. Our cohesive and driven team in South San Francisco is dedicated to curing cancer and saving lives. Seniority level
Seniority level Not Applicable Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at Pattern Biosciences by 2x Get notified about new Scientist jobs in
South San Francisco, CA . Foster City, CA $135,000.00-$185,000.00 1 week ago Hayward, CA $125,000.00-$150,000.00 2 weeks ago Fremont, CA $110,000.00-$115,000.00 3 weeks ago South San Francisco, CA $57,574.40-$110,635.20 3 days ago South San Francisco, CA $100,000.00-$200,000.00 2 days ago Scientist I/II, Biologics Cell Line Development
Alameda, CA $86,700.00-$173,300.00 4 days ago Hayward, CA $125,000.00-$145,000.00 1 week ago Senior Research Associate / Associate Scientist - Polymer
Assoc Scientist R&D, RNA Assay Development
Alameda, CA $86,700.00-$173,300.00 1 week ago Menlo Park, CA $100,000.00-$150,000.00 3 weeks ago Principal Clinical Research Scientist # 4365
Development Associate II to Associate Scientist
Scientist 1/2/Senior Scientist, Analytical Development
Scientist/Senior Scientist, Analytical Chemistry
San Francisco County, CA $75.00-$85.00 3 weeks ago Clinical Variant Interpretation Scientist (Remote)
San Francisco, CA $100,000.00-$150,000.00 1 month ago Research Scientist - Computational Chemistry
Oakland, CA $150,000.00-$185,000.00 1 month ago Scientist/Senior Scientist, Analytical Chemistry
San Mateo County, CA $75.00-$85.00 3 weeks ago Newark, CA $150,000.00-$175,000.00 2 weeks ago San Francisco, CA $145,000.00-$175,000.00 1 day ago Senior Scientist I, Cell/Molecular Biology - Cell Line Development
South San Francisco, CA $94,000.00-$178,500.00 2 weeks ago San Francisco, CA $166,000.00-$244,000.00 2 days ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr