Bristol Myers Squibb
Senior Scientist, Immuno-Oncology, Discovery Biology
Bristol Myers Squibb, Seattle, Washington, us, 98127
Senior Scientist, Immuno-Oncology, Discovery Biology
We are seeking an innovative and motivated immunologist to advance our portfolio of pioneering T cell engager therapeutics to treat cancers. The successful candidate will join the Discovery Biology Team within the Oncology Thematic Research Center at Bristol Myers Squibb in Seattle, WA. The qualified candidate will provide expertise in immunology and will join a multidisciplinary, groundbreaking team driving projects from discovery through IND. Using their knowledge in T cell immunology, the candidate will have the opportunity to identify and validate novel targets and design novel assay systems to enable next‑generation engager cancer therapeutics. This scientist will work in a highly collaborative, dynamic, fast‑paced environment involving multiple teams across the company.
Position Responsibilities
Identify and validate novel targets for development of T cell engagers.
Independently design, develop and execute novel in vitro and ex vivo cell‑based assays/models to evaluate the efficacy and specificity of T cell engagers.
Apply knowledge of T cell biology to develop next‑generation T cell engagers with improved efficacy and safety profiles.
Design and implement critical studies required to drive hypothesis‑driven research.
Collaborate across multiple projects/roles in a matrixed environment.
Present complex concepts to a range of audiences including governance and full team project meetings.
Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders.
Basic Qualifications
Master's Degree and 4+ years of relevant academic and/or industry experience.
Ph.D. or equivalent advanced degree in the Life Sciences and 2+ years of relevant academic and/or industry experience.
Bachelor's Degree and 6+ years of relevant academic and/or industry experience.
Preferred Qualifications
Ph.D. or equivalent advanced degree in immunology, immuno‑oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience.
Knowledge of T cell biology and relevant in vitro assay systems and experience with transformed tumor cells.
Experience with technologies typically employed to engineer cell lines and assess immune cell function including but not limited to CRISPR, RNAi, Luminex, MSD, IncuCyte‑based assays, multi‑parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies.
Demonstration of hypothesis‑driven, in‑depth, innovative thinking and experimentation.
Self‑motivated and focused with project‑management oriented thinking; able to work on multiple projects in a matrix environment.
Ability to communicate well with peers, supervisors, and governance committees.
Strong problem‑solving skills and understanding of complex scientific principles.
Requires strong organizational skills to ensure thorough and timely documentation of experiments, and preparation of data for compiling reports for both internal and external documents.
Experience with antibody drug discovery and target identification/validation is an advantage.
Compensation and Benefits The starting compensation range for this role in Seattle, WA is $131,590 – $159,500, plus incentive cash and stock opportunities (based on eligibility). Eligibility for specific benefits listed on our careers site may vary based on the job and location.
Benefit offerings include medical, pharmacy, dental and vision care; wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP); financial well‑being resources and a 401(k); short- and long‑term disability, life insurance, supplemental health insurance, business travel protection and survivor support; paid national and optional holidays; up to 120 hours of paid vacation; two paid days to volunteer; sick time off; and summer hours flexibility. Additional benefits include parental, caregiver, bereavement, and military leave; family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits; support for traveling mothers; child, elder and pet care resources; tuition reimbursement; and a recognition program.
Equal Employment Opportunity BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws.
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Position Responsibilities
Identify and validate novel targets for development of T cell engagers.
Independently design, develop and execute novel in vitro and ex vivo cell‑based assays/models to evaluate the efficacy and specificity of T cell engagers.
Apply knowledge of T cell biology to develop next‑generation T cell engagers with improved efficacy and safety profiles.
Design and implement critical studies required to drive hypothesis‑driven research.
Collaborate across multiple projects/roles in a matrixed environment.
Present complex concepts to a range of audiences including governance and full team project meetings.
Utilize excellent communication and interpersonal skills to drive collaboration and alignment with key stakeholders.
Basic Qualifications
Master's Degree and 4+ years of relevant academic and/or industry experience.
Ph.D. or equivalent advanced degree in the Life Sciences and 2+ years of relevant academic and/or industry experience.
Bachelor's Degree and 6+ years of relevant academic and/or industry experience.
Preferred Qualifications
Ph.D. or equivalent advanced degree in immunology, immuno‑oncology, tumor immunology, or a related field with 2+ years of relevant academic and/or industry experience.
Knowledge of T cell biology and relevant in vitro assay systems and experience with transformed tumor cells.
Experience with technologies typically employed to engineer cell lines and assess immune cell function including but not limited to CRISPR, RNAi, Luminex, MSD, IncuCyte‑based assays, multi‑parameter flow cytometry, T cell activation assays, T cell proliferation assays, imaging technologies.
Demonstration of hypothesis‑driven, in‑depth, innovative thinking and experimentation.
Self‑motivated and focused with project‑management oriented thinking; able to work on multiple projects in a matrix environment.
Ability to communicate well with peers, supervisors, and governance committees.
Strong problem‑solving skills and understanding of complex scientific principles.
Requires strong organizational skills to ensure thorough and timely documentation of experiments, and preparation of data for compiling reports for both internal and external documents.
Experience with antibody drug discovery and target identification/validation is an advantage.
Compensation and Benefits The starting compensation range for this role in Seattle, WA is $131,590 – $159,500, plus incentive cash and stock opportunities (based on eligibility). Eligibility for specific benefits listed on our careers site may vary based on the job and location.
Benefit offerings include medical, pharmacy, dental and vision care; wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP); financial well‑being resources and a 401(k); short- and long‑term disability, life insurance, supplemental health insurance, business travel protection and survivor support; paid national and optional holidays; up to 120 hours of paid vacation; two paid days to volunteer; sick time off; and summer hours flexibility. Additional benefits include parental, caregiver, bereavement, and military leave; family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits; support for traveling mothers; child, elder and pet care resources; tuition reimbursement; and a recognition program.
Equal Employment Opportunity BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws.
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