The businesses of Merck KGaA, Darmstadt, Germany
Senior Scientist - Immunotherapy
The businesses of Merck KGaA, Darmstadt, Germany, Billerica, Massachusetts, us, 01821
Work Location: Billerica, Massachusetts
Shift: No
Department: HC‑RD‑TM3D Tumor Immunology 3D
Recruiter: Beverly Dellisola
Your Role Help shape the next generation of cancer immunotherapies at EMD Serono in Billerica, MA. As an in vitro Senior Scientist, you will not only execute experiments but also lead and represent the in vitro strategy on discovery teams working on Tumor Immunology projects. Our goal is to mobilize adaptive and innate immunity—spanning antibody therapeutics, T‑cell engagers, checkpoint modulators, and myeloid/NK activators—turning bold ideas into high‑quality clinical candidates in a fast‑paced, highly collaborative environment.
Responsibilities
Design and execute in vitro/ex vivo human immune tumor co‑culture assays; profile function via flow cytometry, cytokine/biomarker readouts, and high‑content imaging.
Build and validate human immunology models that complement animal studies to improve translational predictivity and de‑risk candidates.
Scout, implement, and champion new assay platforms to investigate novel MOAs, boost data quality, throughput, and decision‑making speed.
Independently generate in vitro data for target selection, lead optimization, candidate nomination; and enable program decisions toward IND‑enabling studies.
Analyze, document, and present results to multidisciplinary teams and senior leadership; manage CROs and academic collaborations where needed.
Provide creative, strategic input—conceive new project ideas and help design execution‑ready workplans.
Minimum Qualifications
Master’s degree in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 5+ years of hands‑on immunology/immuno‑oncology (T‑cell biology) experience in academia or industry setting
PhD in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 2+ years post‑PhD of hands‑on immunology/immuno‑oncology (T‑cell biology) experience in academia or industry setting
Preferred Qualifications
Expertise developing, running complex T‑cell functional assays (activation receptors, costimulatory molecules, checkpoint receptors) and interpreting mechanistic data to inform early development. Hands on experience with T‑cell engagers and (ADCs).
Experience in designing, executing, and interpreting in vitro assays for drug discovery, including tumor models and pharmacology experiments
Clear, crisp communicator; highly organized multitasker who adapts quickly to deliver on‑time data packages
Confident influencer who engages senior leadership and thrives in a matrixed organization
Proven scientific impact—publications and contributions advancing new therapeutic concepts
Pay Range for this position: $83,500 - $138,500
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job‑related factors. Position may be eligible for sales or performance‑based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.
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Your Role Help shape the next generation of cancer immunotherapies at EMD Serono in Billerica, MA. As an in vitro Senior Scientist, you will not only execute experiments but also lead and represent the in vitro strategy on discovery teams working on Tumor Immunology projects. Our goal is to mobilize adaptive and innate immunity—spanning antibody therapeutics, T‑cell engagers, checkpoint modulators, and myeloid/NK activators—turning bold ideas into high‑quality clinical candidates in a fast‑paced, highly collaborative environment.
Responsibilities
Design and execute in vitro/ex vivo human immune tumor co‑culture assays; profile function via flow cytometry, cytokine/biomarker readouts, and high‑content imaging.
Build and validate human immunology models that complement animal studies to improve translational predictivity and de‑risk candidates.
Scout, implement, and champion new assay platforms to investigate novel MOAs, boost data quality, throughput, and decision‑making speed.
Independently generate in vitro data for target selection, lead optimization, candidate nomination; and enable program decisions toward IND‑enabling studies.
Analyze, document, and present results to multidisciplinary teams and senior leadership; manage CROs and academic collaborations where needed.
Provide creative, strategic input—conceive new project ideas and help design execution‑ready workplans.
Minimum Qualifications
Master’s degree in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 5+ years of hands‑on immunology/immuno‑oncology (T‑cell biology) experience in academia or industry setting
PhD in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 2+ years post‑PhD of hands‑on immunology/immuno‑oncology (T‑cell biology) experience in academia or industry setting
Preferred Qualifications
Expertise developing, running complex T‑cell functional assays (activation receptors, costimulatory molecules, checkpoint receptors) and interpreting mechanistic data to inform early development. Hands on experience with T‑cell engagers and (ADCs).
Experience in designing, executing, and interpreting in vitro assays for drug discovery, including tumor models and pharmacology experiments
Clear, crisp communicator; highly organized multitasker who adapts quickly to deliver on‑time data packages
Confident influencer who engages senior leadership and thrives in a matrixed organization
Proven scientific impact—publications and contributions advancing new therapeutic concepts
Pay Range for this position: $83,500 - $138,500
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job‑related factors. Position may be eligible for sales or performance‑based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.
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