AstraZeneca
Senior Scientist, Cell Biology Mechanistic Biology and Profiling
AstraZeneca, Waltham, Massachusetts, United States, 02254
Senior Scientist, Cell Biology Mechanistic Biology and Profiling
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Senior Scientist, Cell Biology Mechanistic Biology and Profiling
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AstraZeneca . This is an exciting opportunity for a scientist with expertise in cell biology assay development and execution to contribute to drug discovery projects within AstraZeneca R&D in Waltham, MA. Collaborate with multidisciplinary teams on oncology projects, helping identify and develop high-quality lead compounds for clinical development. Support multiple projects in a dynamic environment. Accountabilities
Develop, validate, and utilize cell biology assays to profile compounds rapidly, informing chemistry and project progression. Responsibilities include: Deliver high-quality cell-based screening data to guide drug design Develop and validate functional assays to meet project needs Stay updated on advancements in cell-based assays for drug discovery Present data and insights at meetings, sharing technical expertise Contribute to multiple drug project teams in a fast-paced setting Work effectively as part of a team to deliver quality leads Qualifications
Ph.D. in Cell Biology, Biology, or related field with 1-3 years post-grad experience OR Master’s with 5-8 years post-grad experience Strong team player with excellent communication skills Proven experience culturing various cell types Successful development of cell-based assays (e.g., AlphaLISAs, HiBiTs, nanoBRETs, proliferation, imaging) Extensive experience with imaging technologies Creative problem-solving skills and ability to improve assay technologies Accurate record-keeping and lab notebook maintenance Proficiency in Microsoft Office Experience supporting oncology programs and culturing primary human cells/organoids is desirable About AstraZeneca
We are committed to science-driven innovation to treat and prevent diseases. Our inclusive environment fosters collaboration across academia and biotech, empowering bold decisions and celebrating successes and failures. We leverage diverse knowledge to maximize impact on disease. Waltham Site
Located in Massachusetts, our facility focuses on small-molecule research with state-of-the-art labs designed to inspire collaboration. We offer amenities like a fitness center, healthcare clinic, EV charging, cafeteria, and flexible workspaces. Upcoming relocation to Kendall Square/Cambridge in 2026 will further enhance our innovative environment. Benefits
Competitive salary, bonus, long-term incentives, generous PTO, and comprehensive benefits. AstraZeneca values diversity and provides accommodations for individuals with disabilities during the application process. Job Details
Seniority level: Mid-Senior level Employment type: Full-time Job functions: Science, Strategy/Planning, Research Industry: Pharmaceutical Manufacturing
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Join to apply for the
Senior Scientist, Cell Biology Mechanistic Biology and Profiling
role at
AstraZeneca . This is an exciting opportunity for a scientist with expertise in cell biology assay development and execution to contribute to drug discovery projects within AstraZeneca R&D in Waltham, MA. Collaborate with multidisciplinary teams on oncology projects, helping identify and develop high-quality lead compounds for clinical development. Support multiple projects in a dynamic environment. Accountabilities
Develop, validate, and utilize cell biology assays to profile compounds rapidly, informing chemistry and project progression. Responsibilities include: Deliver high-quality cell-based screening data to guide drug design Develop and validate functional assays to meet project needs Stay updated on advancements in cell-based assays for drug discovery Present data and insights at meetings, sharing technical expertise Contribute to multiple drug project teams in a fast-paced setting Work effectively as part of a team to deliver quality leads Qualifications
Ph.D. in Cell Biology, Biology, or related field with 1-3 years post-grad experience OR Master’s with 5-8 years post-grad experience Strong team player with excellent communication skills Proven experience culturing various cell types Successful development of cell-based assays (e.g., AlphaLISAs, HiBiTs, nanoBRETs, proliferation, imaging) Extensive experience with imaging technologies Creative problem-solving skills and ability to improve assay technologies Accurate record-keeping and lab notebook maintenance Proficiency in Microsoft Office Experience supporting oncology programs and culturing primary human cells/organoids is desirable About AstraZeneca
We are committed to science-driven innovation to treat and prevent diseases. Our inclusive environment fosters collaboration across academia and biotech, empowering bold decisions and celebrating successes and failures. We leverage diverse knowledge to maximize impact on disease. Waltham Site
Located in Massachusetts, our facility focuses on small-molecule research with state-of-the-art labs designed to inspire collaboration. We offer amenities like a fitness center, healthcare clinic, EV charging, cafeteria, and flexible workspaces. Upcoming relocation to Kendall Square/Cambridge in 2026 will further enhance our innovative environment. Benefits
Competitive salary, bonus, long-term incentives, generous PTO, and comprehensive benefits. AstraZeneca values diversity and provides accommodations for individuals with disabilities during the application process. Job Details
Seniority level: Mid-Senior level Employment type: Full-time Job functions: Science, Strategy/Planning, Research Industry: Pharmaceutical Manufacturing
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