Gilead Sciences, Inc.
Post Doctoral Scientist (CHO Cell Culture)
Gilead Sciences, Inc., Foster City, California, United States, 94420
Post Doctoral Scientist (Biologics Development and Manufacturing)
We are seeking a highly motivated and innovative Postdoctoral Researcher to join the Cell Culture Process Development team at Gilead. The role reports to the Cell Culture Process Development within the Biologics Pivotal & Commercial Organization.
Key Responsibilities:
Design and perform buffer/media preparation and cell culture operations in shake flasks, ambr15, ambr250, bench‑scale bioreactors, and novel platforms.
Lead optimization of chemically defined cell culture media to improve productivity and modulate product quality for fed‑batch and perfusion processes.
Apply statistical and computational tools (DoE, multivariate analysis) to interpret experimental data and guide media formulation strategies.
Elucidate mechanistic understanding of key factors and metabolic pathways related to cell culture medium and process development using advanced bio‑analytical techniques (bioassays, proteomics, metabolomics).
Participate cross‑functionally within and outside biologics technical development to achieve common goals.
Prepare technical reports, protocols, presentations, and manuscripts for internal and external dissemination.
Occasional weekend work may be required to support cell culture operations.
Maintain accurate laboratory records in compliance with institutional and regulatory standards.
Adhere to department budget and all training, compliance and safety requirements, and support general laboratory upkeep.
Basic Qualifications:
Ph.D. in Biology, Biochemistry, Bioengineering, Chemical Engineering, or Biomolecular Engineering with 0‑2 years of relevant experience or expected Ph.D. graduation within 6 months.
Motivated self‑starter with organizational and problem‑solving skills; excellent verbal communication, presentation, and scientific writing skills.
Technical proficiency, scientific creativity, collaboration, and independent experimental design capability.
Passion for inclusion and understanding the business value of diverse teams.
Preferred Qualifications:
Hands‑on laboratory experience in CHO cell culture including shake flasks, high‑throughput bioreactors (ambr15, ambr250), and bench‑scale bioreactors in parallel operation.
Experience with serum‑free, chemically defined media optimization.
Solid understanding of CHO cell metabolism, bioprocessing, and media formulation principles.
Experience with metabolic pathway analysis tools and bio‑analytical techniques such as proteomics, metabolomics, and bioassays for gene expression analysis.
Experience with kinetic modeling and computational tools (Python, R, MATLAB).
Experience in statistics, design‑of‑experiments, and data analysis (JMP, Spotfire).
Proven track record of external presentations and/or publications in peer‑reviewed journals.
Salary and Benefits:
$126,820.00 – $164,120.00 base pay, eligible for paid time off and benefits including medical, dental, vision, and life insurance. No discretionary annual bonus or long‑term incentives.
Equal Employment Opportunity:
Gilead Sciences Inc. is committed to equal employment opportunities. We welcome applicants of all backgrounds and uphold protections against discrimination. For more information, please visit our
benefits page .
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Key Responsibilities:
Design and perform buffer/media preparation and cell culture operations in shake flasks, ambr15, ambr250, bench‑scale bioreactors, and novel platforms.
Lead optimization of chemically defined cell culture media to improve productivity and modulate product quality for fed‑batch and perfusion processes.
Apply statistical and computational tools (DoE, multivariate analysis) to interpret experimental data and guide media formulation strategies.
Elucidate mechanistic understanding of key factors and metabolic pathways related to cell culture medium and process development using advanced bio‑analytical techniques (bioassays, proteomics, metabolomics).
Participate cross‑functionally within and outside biologics technical development to achieve common goals.
Prepare technical reports, protocols, presentations, and manuscripts for internal and external dissemination.
Occasional weekend work may be required to support cell culture operations.
Maintain accurate laboratory records in compliance with institutional and regulatory standards.
Adhere to department budget and all training, compliance and safety requirements, and support general laboratory upkeep.
Basic Qualifications:
Ph.D. in Biology, Biochemistry, Bioengineering, Chemical Engineering, or Biomolecular Engineering with 0‑2 years of relevant experience or expected Ph.D. graduation within 6 months.
Motivated self‑starter with organizational and problem‑solving skills; excellent verbal communication, presentation, and scientific writing skills.
Technical proficiency, scientific creativity, collaboration, and independent experimental design capability.
Passion for inclusion and understanding the business value of diverse teams.
Preferred Qualifications:
Hands‑on laboratory experience in CHO cell culture including shake flasks, high‑throughput bioreactors (ambr15, ambr250), and bench‑scale bioreactors in parallel operation.
Experience with serum‑free, chemically defined media optimization.
Solid understanding of CHO cell metabolism, bioprocessing, and media formulation principles.
Experience with metabolic pathway analysis tools and bio‑analytical techniques such as proteomics, metabolomics, and bioassays for gene expression analysis.
Experience with kinetic modeling and computational tools (Python, R, MATLAB).
Experience in statistics, design‑of‑experiments, and data analysis (JMP, Spotfire).
Proven track record of external presentations and/or publications in peer‑reviewed journals.
Salary and Benefits:
$126,820.00 – $164,120.00 base pay, eligible for paid time off and benefits including medical, dental, vision, and life insurance. No discretionary annual bonus or long‑term incentives.
Equal Employment Opportunity:
Gilead Sciences Inc. is committed to equal employment opportunities. We welcome applicants of all backgrounds and uphold protections against discrimination. For more information, please visit our
benefits page .
#J-18808-Ljbffr