Post Doctoral Scientist (Biologics Development and Manufacturing)

* Design experiments and perform hands-on buffer/media preparation and cell culture operations in shake flasks, ambr15, ambr250, bench-scale bioreactors, and novel cell culture platforms* Lead aspects of optimizing chemically defined cell culture media to improve productivity and modulate product quality for fed-batch and perfusion processes* Apply statistical and computational tools (e.g., DoE, multivariate analysis) to interpret experimental data and guide media formulation strategies* Elucidate mechanistic understanding of key factors and associated metabolic pathways relating to cell culture medium and process development using advanced bio-analytical techniques such as bioassays, proteomics, and metabolomics* Participate and work cross-functionally within and outside of biologics technical development to achieve common goals* Prepare technical reports, protocols, presentations, and manuscripts for internal and external dissemination* Occasional weekend work may be required to support cell culture operations* Maintain accurate and detailed laboratory records in compliance with institutional and regulatory standards* Adhere to department budget and all training, compliance and safety requirements. Support general laboratory upkeep.* Ph.D. in a relevant scientific discipline (Biology, Biochemistry, Bioengineering, Chemical Engineering, Biomolecular Engineering) with 0-2 years of relevant experience OR expected PhD graduation within 6 months from date of application* Motivated self-starter with organizational and problem-solving skills. Excellent verbal communication, oral presentation, and scientific writing skills* Demonstrates technical proficiency, scientific creativity, collaboration with others and independent thought in suggesting experimental design* Passion for inclusion: knowing the business value of diverse teams, modelling inclusion, and embedding the value of diversity in the way they work* Hands-on laboratory operations experience in CHO cell culture including shake flask, high-throughput bioreactor (e.g., ambr15, ambr250), bench scale bioreactor in parallel operation* Experience with serum-free, chemically defined media optimization* Solid understanding of CHO cell metabolism, bioprocessing, and media formulation principles* Experience with tools for metabolic pathway analyses and bio-analytical techniques such as proteomics, metabolomics, and bioassays for gene expression analysis to guide media optimization* Experience with kinetic modeling and computational tools (e.g., Python, R, MATLAB)* Experience in statistics, design-of-experiments, and data analysis (e.g. JMP, Spotfire)* Proven track record of external presentations and/or publications in peer-reviewed journalsGilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
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