GondolaBio, LLC
Principal Scientist, Translational Research
GondolaBio, LLC, Palo Alto, California, United States, 94306
All Jobs > Principal Scientist, Translational Research
Principal Scientist, Translational Research Palo Alto, CA
Description Company Background GondolaBio is a collection of biopharmaceutical companies focused on developing next‑generation therapeutics for genetic diseases. Originally carved out of BridgeBio, GondolaBio secured $300M in private financing from external investors in 2024 and became an independent company within the BridgeBio ecosystem. GondolaBio aims to leverage cutting‑edge biological research to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases.
Who You Are We seek an entrepreneurial scientist to drive the biology and translational research for Portal Therapeutics. You will be supporting strategy and direction, assay development, mouse model experimentation, preclinical dose guidance, regulatory document writing including INDs, and other translational biology and pharmacology experiments through a combination of internal and external efforts. This job requires excellent communication and interpersonal skills as well as technical and scientific abilities. We hope to hear from you.
Requirements Responsibilities
Support critical translational studies that further elucidate the mechanism, biology, and understanding of the Portal drug
Support biology, pharmacology, and translational research for Portal
Understanding of the biology and pharmacology of the relevant disease area and treatment approaches
Manage relationships with CROs for efficient execution of all the preclinical and translational studies
Collaborate with cross‑functional teams, including DMPK, toxicology, clinical development, regulatory to advance our therapeutic candidates through clinical development in a fast‑paced, dynamic environment
Represent the program scientifically to internal and external audiences
Contribute to due diligence and gap analysis on potential new GondolaBio assets
Education, Experience & Skills Requirements
Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or related discipline with
6+ years
of industry experience in bioanalytical sciences; or M.S. with
10+ years .
Strong scientific background and achievements in bioscience and translational, ideally demonstrated by scientific publications, presentations, and/or patents
Proven track record of successfully working in research programs and teams
Strong understanding of drug discovery and development processes
Excellent communication, leadership, and organizational skills
Ability to think strategically and execute effectively
Experience in collaborating with cross‑functional teams and external partners
Knowledge of regulatory requirements and industry standards
Demonstrate creative 'out of the box' thinking to solve complex technical problems and champion innovative technologies to achieve project goals
Commitment, drive, and ownership mindset
What We Offer
Patient Days, where we are fortunate enough to learn more about the lives we are looking to impact and a real exchange of ideas as to how we can improve our efforts
A culture inspired by our values: put patients first; think independently; be radically transparent; every minute counts; and let the science speak
Collaborative business environment
Excellent compensation package (Base, Performance Bonus, Equity)
Excellent benefits package
Flexible PTO
A fast‑paced, data‑driven, work environment with world‑class R&D minds and capabilities
Work with the most productive groups of R&D operators in the industry
A platform for meaningful scientific contributions to shine
The base pay range for this position is $185,000 to $210,000 per year. The actual compensation offered will be determined based on a number of job‑related factors, including experience, skills, qualifications, and location. A bonus plan and equity will also be offered.
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Principal Scientist, Translational Research Palo Alto, CA
Description Company Background GondolaBio is a collection of biopharmaceutical companies focused on developing next‑generation therapeutics for genetic diseases. Originally carved out of BridgeBio, GondolaBio secured $300M in private financing from external investors in 2024 and became an independent company within the BridgeBio ecosystem. GondolaBio aims to leverage cutting‑edge biological research to discover, create, test, and deliver transformative medicines to treat patients who suffer from genetic diseases.
Who You Are We seek an entrepreneurial scientist to drive the biology and translational research for Portal Therapeutics. You will be supporting strategy and direction, assay development, mouse model experimentation, preclinical dose guidance, regulatory document writing including INDs, and other translational biology and pharmacology experiments through a combination of internal and external efforts. This job requires excellent communication and interpersonal skills as well as technical and scientific abilities. We hope to hear from you.
Requirements Responsibilities
Support critical translational studies that further elucidate the mechanism, biology, and understanding of the Portal drug
Support biology, pharmacology, and translational research for Portal
Understanding of the biology and pharmacology of the relevant disease area and treatment approaches
Manage relationships with CROs for efficient execution of all the preclinical and translational studies
Collaborate with cross‑functional teams, including DMPK, toxicology, clinical development, regulatory to advance our therapeutic candidates through clinical development in a fast‑paced, dynamic environment
Represent the program scientifically to internal and external audiences
Contribute to due diligence and gap analysis on potential new GondolaBio assets
Education, Experience & Skills Requirements
Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or related discipline with
6+ years
of industry experience in bioanalytical sciences; or M.S. with
10+ years .
Strong scientific background and achievements in bioscience and translational, ideally demonstrated by scientific publications, presentations, and/or patents
Proven track record of successfully working in research programs and teams
Strong understanding of drug discovery and development processes
Excellent communication, leadership, and organizational skills
Ability to think strategically and execute effectively
Experience in collaborating with cross‑functional teams and external partners
Knowledge of regulatory requirements and industry standards
Demonstrate creative 'out of the box' thinking to solve complex technical problems and champion innovative technologies to achieve project goals
Commitment, drive, and ownership mindset
What We Offer
Patient Days, where we are fortunate enough to learn more about the lives we are looking to impact and a real exchange of ideas as to how we can improve our efforts
A culture inspired by our values: put patients first; think independently; be radically transparent; every minute counts; and let the science speak
Collaborative business environment
Excellent compensation package (Base, Performance Bonus, Equity)
Excellent benefits package
Flexible PTO
A fast‑paced, data‑driven, work environment with world‑class R&D minds and capabilities
Work with the most productive groups of R&D operators in the industry
A platform for meaningful scientific contributions to shine
The base pay range for this position is $185,000 to $210,000 per year. The actual compensation offered will be determined based on a number of job‑related factors, including experience, skills, qualifications, and location. A bonus plan and equity will also be offered.
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