Brigham and Women's Hospital
Research Lab Tech II NEUROLOGY KL
Brigham and Women's Hospital, Boston, Massachusetts, us, 02298
Summary
The position is for a TRA2 in the Kuchroo Lab at the Department of Neurology, BWH. Working very independently, under very general supervision, this role executes protocols involving a variety of routine and non‑routine experiments at a professional level, may identify new techniques, and develops modification of existing techniques as appropriate. In collaboration with other members of the research team, the trainee will give input to the development of design protocols. The trainee calculates, transcribes, and analyzes data using statistical techniques and may be responsible for orienting and training new staff. This position involves extensive training at the initial stage and requires a minimum two‑year commitment. The person in this role will carry out a broad range of technically advanced research activities and procedures, evaluate conclusions, and have considerable latitude to modify or devise methods and techniques as necessary to achieve desired results. They will typically supervise technical and sometimes administrative elements of the research unit.
Essential Functions
Independently performs routine and non‑routine experiments, playing an integral role in wet laboratory techniques, including tissue harvesting, cell and microbial culture, and molecular biology methodologies.
Animal husbandry experience, specifically breeding mouse strains, weanings, crosses, genotyping, cryopreservation, exporting mice, and importing mice from outside collaborators.
Experiments may include specific assays, tissue culture, PCR analyzing in vitro experiments, and in‑vivo disease models (EAE, colitis, tumor models).
Calculate, transcribe, and analyze data using advanced statistical techniques.
Maintain long‑term tissue cultures of human and mouse cell lines and monitor cells for viability and contamination.
Perform literature searches and help to prepare presentations and written articles for publication.
In collaboration with PI or Research Manager, establish new and modify existing research techniques.
Coordinate schedule of tests and procedures, contributing to the generation of protocols and documents.
Coordinate lab activities such as infection control, radiation safety, and biosafety activities.
Prepare, order, and maintain stock of necessary lab reagents, solutions, and supplies.
Operate and maintain laboratory equipment.
Assist in the orientation and training of new staff.
Execute protocols of non‑routine experiments.
Assist PI with determining the most suitable methodology.
Perform basic design and modification of protocols.
Calculate, transcribe, and analyze data.
Prepare and present reports.
Organize and summarize acquired data using scientific and statistical techniques.
Participate in the design of experiments or field work.
Perform all other duties as assigned.
Education Bachelor's degree in a biological or physical science required.
Experience Previous research lab experience of 1-2 years required.
Qualifications
Must have at least one year experience in a directly related research setting.
Excellent interpersonal and collaborative skills.
Ability to work independently and as part of a team.
High level of initiative and ability to work with little supervision.
Hands‑on experience in molecular biology, genomics, and cellular biology (cell-based assays, cell culture) helpful.
Computer literacy and working knowledge of data management systems.
Knowledge, Skills and Abilities
High degree of computer literacy.
Sound analytical and organizational skills.
Good oral and written communication skills.
Ability to logically and effectively structure tasks and set priorities.
Ability to identify potential problems and troubleshoot solutions.
Demonstrated ability to analyze data statistically and to logically present it.
Analytical skills and ability to resolve technical problems.
Ability to interpret acceptability of data results.
Strong computer skills.
Demonstrated competence in research techniques and methodologies.
Equal Employment Opportunity Statement The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives, and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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Essential Functions
Independently performs routine and non‑routine experiments, playing an integral role in wet laboratory techniques, including tissue harvesting, cell and microbial culture, and molecular biology methodologies.
Animal husbandry experience, specifically breeding mouse strains, weanings, crosses, genotyping, cryopreservation, exporting mice, and importing mice from outside collaborators.
Experiments may include specific assays, tissue culture, PCR analyzing in vitro experiments, and in‑vivo disease models (EAE, colitis, tumor models).
Calculate, transcribe, and analyze data using advanced statistical techniques.
Maintain long‑term tissue cultures of human and mouse cell lines and monitor cells for viability and contamination.
Perform literature searches and help to prepare presentations and written articles for publication.
In collaboration with PI or Research Manager, establish new and modify existing research techniques.
Coordinate schedule of tests and procedures, contributing to the generation of protocols and documents.
Coordinate lab activities such as infection control, radiation safety, and biosafety activities.
Prepare, order, and maintain stock of necessary lab reagents, solutions, and supplies.
Operate and maintain laboratory equipment.
Assist in the orientation and training of new staff.
Execute protocols of non‑routine experiments.
Assist PI with determining the most suitable methodology.
Perform basic design and modification of protocols.
Calculate, transcribe, and analyze data.
Prepare and present reports.
Organize and summarize acquired data using scientific and statistical techniques.
Participate in the design of experiments or field work.
Perform all other duties as assigned.
Education Bachelor's degree in a biological or physical science required.
Experience Previous research lab experience of 1-2 years required.
Qualifications
Must have at least one year experience in a directly related research setting.
Excellent interpersonal and collaborative skills.
Ability to work independently and as part of a team.
High level of initiative and ability to work with little supervision.
Hands‑on experience in molecular biology, genomics, and cellular biology (cell-based assays, cell culture) helpful.
Computer literacy and working knowledge of data management systems.
Knowledge, Skills and Abilities
High degree of computer literacy.
Sound analytical and organizational skills.
Good oral and written communication skills.
Ability to logically and effectively structure tasks and set priorities.
Ability to identify potential problems and troubleshoot solutions.
Demonstrated ability to analyze data statistically and to logically present it.
Analytical skills and ability to resolve technical problems.
Ability to interpret acceptability of data results.
Strong computer skills.
Demonstrated competence in research techniques and methodologies.
Equal Employment Opportunity Statement The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives, and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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