Dana-Farber Cancer Institute
Research Technician – Antibody Discovery and Chimeric Antigen Receptor (CAR) Pro
Dana-Farber Cancer Institute, Boston, Massachusetts, us, 02298
Research Technician – Antibody Discovery and CAR Production & Characterization
Join to apply for the
Research Technician – Antibody Discovery and CAR Production & Characterization
role at
Dana‑Farber Cancer Institute
Dana‑Farber Cancer Institute is seeking a research technician to join the
L ab for
A ntibody and
N anobody
P hage Display and
D iscovery (LAUNCHPAD), a pre‑clinical research group with the mission to streamline “discovery to translation” of antibody‑based immunotherapies for cancer. The LAUNCHPAD team works closely with DFCI PIs to implement the discovery and functional screening of antibody ‘hits’ as well as the engineering of hits to generate potential therapeutic antibody‑based biologics and cell therapies. The candidate should be motivated to learn and execute workflows for antibody discovery via in vitro display as well as the production, screening, and characterization of candidate antibody and CAR T cell therapies. Additionally, another key aspect of this role will be to work closely with LAUNCHPAD’s team members to support and help manage the group’s lab operations and logistics.
Responsibilities
Help manage consumable/reagent inventory; track, order and maintain key lab supplies.
Support enforcement of lab policies, organizational strategies and procedures (e.g., unpacking/stocking deliveries, ensuring compliance with PPE).
Work closely with Lead Scientist/Head of Research and key personnel to oversee accurate laboratory records, reports, and data; support notebook audits and reviews.
Execute phage and yeast display workflows to identify new, fully human VHH and scFv binders.
Conduct biochemical, molecular and/or cell biology experiments, contributing to production, purification and binding/functional characterization of monospecific and multi‑specific antibodies.
Produce and functionally screen CARs and antibodies to identify leads for clinical translation.
Analyze experimental data, interpret results, write reports and summaries of findings; participate in formal and informal presentations.
Maintain detailed electronic notebook; document samples, methods and observations.
Develop, improve and adhere to standard operating procedures.
Proactively steward the laboratory.
Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
Commit intellectually by keeping up with relevant literature and actively participating in lab meetings, journal club and research seminars.
Qualifications
BS or MS in a relevant field (Biology, Bioengineering, Chemical Engineering, etc.) with experience in molecular, protein or cell biology.
Full‑time research lab experience (academic or biotech/pharma) is required.
Previous experience helping manage a laboratory or research group is highly preferred.
Self‑motivated, dedicated and reliable.
Follows standard practices and procedures.
Builds stable working relationships; works with a wide range of faculty and staff.
Excellent written and verbal communication skills.
Outstanding planning, organizational and multi‑tasking skills.
Attention to detail and thoroughness in completing work tasks.
Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$47,500 - $51,300
Equal Opportunity Statement Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
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Research Technician – Antibody Discovery and CAR Production & Characterization
role at
Dana‑Farber Cancer Institute
Dana‑Farber Cancer Institute is seeking a research technician to join the
L ab for
A ntibody and
N anobody
P hage Display and
D iscovery (LAUNCHPAD), a pre‑clinical research group with the mission to streamline “discovery to translation” of antibody‑based immunotherapies for cancer. The LAUNCHPAD team works closely with DFCI PIs to implement the discovery and functional screening of antibody ‘hits’ as well as the engineering of hits to generate potential therapeutic antibody‑based biologics and cell therapies. The candidate should be motivated to learn and execute workflows for antibody discovery via in vitro display as well as the production, screening, and characterization of candidate antibody and CAR T cell therapies. Additionally, another key aspect of this role will be to work closely with LAUNCHPAD’s team members to support and help manage the group’s lab operations and logistics.
Responsibilities
Help manage consumable/reagent inventory; track, order and maintain key lab supplies.
Support enforcement of lab policies, organizational strategies and procedures (e.g., unpacking/stocking deliveries, ensuring compliance with PPE).
Work closely with Lead Scientist/Head of Research and key personnel to oversee accurate laboratory records, reports, and data; support notebook audits and reviews.
Execute phage and yeast display workflows to identify new, fully human VHH and scFv binders.
Conduct biochemical, molecular and/or cell biology experiments, contributing to production, purification and binding/functional characterization of monospecific and multi‑specific antibodies.
Produce and functionally screen CARs and antibodies to identify leads for clinical translation.
Analyze experimental data, interpret results, write reports and summaries of findings; participate in formal and informal presentations.
Maintain detailed electronic notebook; document samples, methods and observations.
Develop, improve and adhere to standard operating procedures.
Proactively steward the laboratory.
Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
Commit intellectually by keeping up with relevant literature and actively participating in lab meetings, journal club and research seminars.
Qualifications
BS or MS in a relevant field (Biology, Bioengineering, Chemical Engineering, etc.) with experience in molecular, protein or cell biology.
Full‑time research lab experience (academic or biotech/pharma) is required.
Previous experience helping manage a laboratory or research group is highly preferred.
Self‑motivated, dedicated and reliable.
Follows standard practices and procedures.
Builds stable working relationships; works with a wide range of faculty and staff.
Excellent written and verbal communication skills.
Outstanding planning, organizational and multi‑tasking skills.
Attention to detail and thoroughness in completing work tasks.
Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$47,500 - $51,300
Equal Opportunity Statement Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
#J-18808-Ljbffr