WuXi AppTec
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Scientist II
role at
WuXi AppTec .
WuXi AppTec company, San Diego, CA is seeking a self‑motivated and skillful scientist to join our target discovery team.
Responsibilities
Perform research efforts for cell based assays, target validation, hit confirmation, and mechanism of action studies
Ability to independently design in vitro studies or with minimal instructions
Excellent acknowledge of immunology, molecular and cell biology
Proficient in executing various cell-based assays with high assay development and troubleshooting skills
Accurately interpret data, communicate experimental results and generate project reports
Ability to search and utilize literatures and external resources to support internal studies
Perform job specific tasks in compliance with applicable regulations, WuXi AppTec policies and Standard Operating Procedures
Qualifications
PhD in immunology, cell biology, pharmacology or closely related fields with 4-6 years of relevant work experience
Knowledge / Skills / Abilities
Deep understanding of immunology, including T-cell and B-cell biology, antigen presentation, cytokine/chemokine pathways, innate and adaptive immune mechanisms, and immune activation/tolerance
Hands‑on experience with immune assays, such as: multicolor flow cytometry (panel design, staining, and data analysis), co-culture systems (immune‑tumor, immune‑epithelial, APC‑T cell, etc.), functional immune readouts (activation markers, cytokine release, proliferation, cytotoxicity), immunogenicity assays (e.g. ADA)
Strong expertise in primary and cell‑line culture, DNA/RNA transfection, viral vector production/infection, immunoblotting, qPCR/ddPCR, MSD, ELISA and other plate‑based assay platforms
Experience with CRISPR genome editing, overexpression and stable cell line development
Proficiency in GraphPad Prism and other data analysis software
Demonstrated ability to manage and prioritize multiple projects across different therapeutic areas
Ability to work effectively in a fast‑paced, dynamic environment, with flexibility to adapt to evolving priorities
Excellent verbal and written communication skills, including clear data presentation and documentation
Strong organizational and record‑keeping skills with high attention to detail
Commitment to high scientific rigor, integrity, and quality in all aspects of research
Physical Requirements
Must be able to work in a lab setting with exposure to chemical and biohazards
Must be able to wear appropriate PPE
Must have clarity of vision
Must be able to perform activities with repetitive motions
Anticipated base pay range:
$80,322 to $104,011
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job‑related duties as requested by Management.
Seniority level
Mid‑Senior level
Employment type
Full‑time
Job function
Research, Analyst, and Information Technology
Industries
Pharmaceutical Manufacturing
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Scientist II
role at
WuXi AppTec .
WuXi AppTec company, San Diego, CA is seeking a self‑motivated and skillful scientist to join our target discovery team.
Responsibilities
Perform research efforts for cell based assays, target validation, hit confirmation, and mechanism of action studies
Ability to independently design in vitro studies or with minimal instructions
Excellent acknowledge of immunology, molecular and cell biology
Proficient in executing various cell-based assays with high assay development and troubleshooting skills
Accurately interpret data, communicate experimental results and generate project reports
Ability to search and utilize literatures and external resources to support internal studies
Perform job specific tasks in compliance with applicable regulations, WuXi AppTec policies and Standard Operating Procedures
Qualifications
PhD in immunology, cell biology, pharmacology or closely related fields with 4-6 years of relevant work experience
Knowledge / Skills / Abilities
Deep understanding of immunology, including T-cell and B-cell biology, antigen presentation, cytokine/chemokine pathways, innate and adaptive immune mechanisms, and immune activation/tolerance
Hands‑on experience with immune assays, such as: multicolor flow cytometry (panel design, staining, and data analysis), co-culture systems (immune‑tumor, immune‑epithelial, APC‑T cell, etc.), functional immune readouts (activation markers, cytokine release, proliferation, cytotoxicity), immunogenicity assays (e.g. ADA)
Strong expertise in primary and cell‑line culture, DNA/RNA transfection, viral vector production/infection, immunoblotting, qPCR/ddPCR, MSD, ELISA and other plate‑based assay platforms
Experience with CRISPR genome editing, overexpression and stable cell line development
Proficiency in GraphPad Prism and other data analysis software
Demonstrated ability to manage and prioritize multiple projects across different therapeutic areas
Ability to work effectively in a fast‑paced, dynamic environment, with flexibility to adapt to evolving priorities
Excellent verbal and written communication skills, including clear data presentation and documentation
Strong organizational and record‑keeping skills with high attention to detail
Commitment to high scientific rigor, integrity, and quality in all aspects of research
Physical Requirements
Must be able to work in a lab setting with exposure to chemical and biohazards
Must be able to wear appropriate PPE
Must have clarity of vision
Must be able to perform activities with repetitive motions
Anticipated base pay range:
$80,322 to $104,011
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job‑related duties as requested by Management.
Seniority level
Mid‑Senior level
Employment type
Full‑time
Job function
Research, Analyst, and Information Technology
Industries
Pharmaceutical Manufacturing
#J-18808-Ljbffr