Bristol Myers Squibb
Scientist or Senior Scientist, Cell Line Development
Bristol Myers Squibb, New Brunswick, New Jersey, us, 08933
Scientist or Senior Scientist, Cell Line Development
Join to apply for the
Scientist or Senior Scientist, Cell Line Development
role at
Bristol Myers Squibb
Working with Us Challenging. Meaningful. Life‑changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
Position Summary We are seeking an enthusiastic candidate to join Bristol Myers Squibb's Cell Line Development team in New Brunswick, New Jersey. This group is part of the larger GUCLD (Global Upstream and Cell Line Development) organization, which primarily focuses on delivering high‑quality cell lines and cell culture processes to advance clinical and commercial programs. This position involves fundamental responsibilities, including the development of expression vectors and mammalian cell lines for the production of monoclonal antibodies, bi‑specific antibodies, and antibody‑drug conjugates, and requires close collaboration across functions with upstream, downstream, analytical development, and R&D teams.
The successful candidate will leverage expertise in protein folding, trafficking, and advanced cell engineering to drive innovation in mammalian cell line development for recombinant protein production. This role requires strong experimental skills, scientific leadership, and the ability to collaborate effectively in cross‑functional teams within a fast‑paced research environment. This position offers excellent opportunities for professional growth and career development in biologics process development.
Key Responsibilities
Lead cell line development projects and perform key activities associated with production cell line development, including transfection, selection, single cell cloning, high‑throughput screening, characterization of clonal cell lines using scale‑down models, cell banking, and cell line stability studies.
Design and optimize mammalian expression vectors and systems; perform transcript quantitation and genetic characterization as needed.
Serve as a subject matter expert to support cell line development in cross‑functional CMC teams, as well as author and review regulatory filings for early and late‑stage projects.
Evaluate and introduce innovative technologies to optimize therapeutic protein folding and production.
Generate hypotheses, plan and execute experiments, analyze data, and draw actionable conclusions.
Collaborate closely with upstream, downstream, and analytical development teams.
Present technical summaries to peers and upper management, as well as prepare technical writing for development reports and regulatory filing support. Publish and/or present scientific findings at external conferences.
Qualifications & Experience
Scientist: Ph.D. in Biological Sciences, Bioengineering, Chemical Engineering, or relevant disciplines, with 0‑2 years of relevant experience or M.S. with 2‑4 years relevant experience or B.S. with 5‑7 years relevant experience.
Senior Scientist: Ph.D. in Biological Sciences, Bioengineering, Chemical Engineering, or relevant disciplines, with 2‑4 years of relevant experience or M.S. with 4‑6 years relevant experience or B.S. with 7‑9 years relevant experience.
Hands‑on experience in mammalian cell line development. Familiarity with Western blotting, cell staining, and FACS sorting.
Strong molecular biology skills in vector design, plasmid construction, cloning, purification, and characterization.
Proficient in transcript quantification and genetic characterization, with hands‑on experience in RNA‑based technologies such as siRNA and miRNA.
In‑depth knowledge of protein and antibody folding and trafficking in the cell.
Experience with advanced cell engineering, omics, and synthetic biology is preferred.
Experience operating AMBR microbioreactors and automated liquid handling systems is a plus.
Strong organizational skills and a proven ability to independently lead scientific projects from hypothesis generation through execution and conclusion. Demonstrated ability to think critically and possess excellent problem‑solving skills.
Excellent collaboration, oral, and written communication skills; demonstrated success working in cross‑functional teams and contributing to shared goals in a fast‑paced research environment.
Proven record of publication in peer‑reviewed journals and presentations at conferences.
Compensation Overview New Brunswick - NJ - US: $96,340 - $116,740 (starting compensation range for full‑time employee).
Additional incentive cash and stock opportunities (based on eligibility) may be available. Final, individual compensation will be decided based on demonstrated experience.
Uniquely Interesting Work, Life‑changing Careers With a single vision as inspiring as Transforming patients' lives through science™, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On‑site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. (Description omitted for conciseness).
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Scientist or Senior Scientist, Cell Line Development
role at
Bristol Myers Squibb
Working with Us Challenging. Meaningful. Life‑changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high‑achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
Position Summary We are seeking an enthusiastic candidate to join Bristol Myers Squibb's Cell Line Development team in New Brunswick, New Jersey. This group is part of the larger GUCLD (Global Upstream and Cell Line Development) organization, which primarily focuses on delivering high‑quality cell lines and cell culture processes to advance clinical and commercial programs. This position involves fundamental responsibilities, including the development of expression vectors and mammalian cell lines for the production of monoclonal antibodies, bi‑specific antibodies, and antibody‑drug conjugates, and requires close collaboration across functions with upstream, downstream, analytical development, and R&D teams.
The successful candidate will leverage expertise in protein folding, trafficking, and advanced cell engineering to drive innovation in mammalian cell line development for recombinant protein production. This role requires strong experimental skills, scientific leadership, and the ability to collaborate effectively in cross‑functional teams within a fast‑paced research environment. This position offers excellent opportunities for professional growth and career development in biologics process development.
Key Responsibilities
Lead cell line development projects and perform key activities associated with production cell line development, including transfection, selection, single cell cloning, high‑throughput screening, characterization of clonal cell lines using scale‑down models, cell banking, and cell line stability studies.
Design and optimize mammalian expression vectors and systems; perform transcript quantitation and genetic characterization as needed.
Serve as a subject matter expert to support cell line development in cross‑functional CMC teams, as well as author and review regulatory filings for early and late‑stage projects.
Evaluate and introduce innovative technologies to optimize therapeutic protein folding and production.
Generate hypotheses, plan and execute experiments, analyze data, and draw actionable conclusions.
Collaborate closely with upstream, downstream, and analytical development teams.
Present technical summaries to peers and upper management, as well as prepare technical writing for development reports and regulatory filing support. Publish and/or present scientific findings at external conferences.
Qualifications & Experience
Scientist: Ph.D. in Biological Sciences, Bioengineering, Chemical Engineering, or relevant disciplines, with 0‑2 years of relevant experience or M.S. with 2‑4 years relevant experience or B.S. with 5‑7 years relevant experience.
Senior Scientist: Ph.D. in Biological Sciences, Bioengineering, Chemical Engineering, or relevant disciplines, with 2‑4 years of relevant experience or M.S. with 4‑6 years relevant experience or B.S. with 7‑9 years relevant experience.
Hands‑on experience in mammalian cell line development. Familiarity with Western blotting, cell staining, and FACS sorting.
Strong molecular biology skills in vector design, plasmid construction, cloning, purification, and characterization.
Proficient in transcript quantification and genetic characterization, with hands‑on experience in RNA‑based technologies such as siRNA and miRNA.
In‑depth knowledge of protein and antibody folding and trafficking in the cell.
Experience with advanced cell engineering, omics, and synthetic biology is preferred.
Experience operating AMBR microbioreactors and automated liquid handling systems is a plus.
Strong organizational skills and a proven ability to independently lead scientific projects from hypothesis generation through execution and conclusion. Demonstrated ability to think critically and possess excellent problem‑solving skills.
Excellent collaboration, oral, and written communication skills; demonstrated success working in cross‑functional teams and contributing to shared goals in a fast‑paced research environment.
Proven record of publication in peer‑reviewed journals and presentations at conferences.
Compensation Overview New Brunswick - NJ - US: $96,340 - $116,740 (starting compensation range for full‑time employee).
Additional incentive cash and stock opportunities (based on eligibility) may be available. Final, individual compensation will be decided based on demonstrated experience.
Uniquely Interesting Work, Life‑changing Careers With a single vision as inspiring as Transforming patients' lives through science™, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On‑site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. (Description omitted for conciseness).
#J-18808-Ljbffr