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Job Description
Vividion is a next-generation biotechnology company based in San Diego that leverages its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology enables us to screen, identify, and optimize novel drugs that selectively bind to virtually any protein, including those previously considered “undruggable”. Our pipeline and emerging programs reflect a mature and productive platform capable of delivering first-in-class drugs with novel mechanisms of action such as allosteric inhibitors, protein-protein interaction inhibitors, functional activators, and degraders against undruggable targets in oncology and immunology. We value scientific excellence, creativity, and teamwork. We are committed to ongoing innovation and have fostered a collaborative, dynamic work culture where your ideas and discoveries are valued and impactful. As we grow, opportunities for mentorship and career progression are available. Job Summary
Vividion Therapeutics is seeking a scientist passionate about harnessing proteomics to probe biology and identify new drug targets. The successful candidate will contribute to identifying novel chemical matter and undruggable targets using our state-of-the-art chemical proteomics platform. Responsibilities include performing mass-spectrometry-based proteomics and molecular biology experiments to support discovery, enablement, and pre-clinical projects. Additionally, the candidate will help expand our platform by implementing high-throughput workflows for new chemical probes. Requirements
Experience and Education
Ph.D. (or equivalent experience) in mass-spectrometry based proteomics or chemical biology Experience operating and maintaining orbitrap mass spectrometers and nano-LC systems Proven experience in acquiring, analyzing, and interpreting proteomics datasets (e.g., PRM, TMT, DIA); targeted proteomics experience is a plus Experience preparing samples for MS analysis, including peptide, protein, or PTM enrichment workflows Experience transforming low-throughput assays into robust high-throughput assays Background in chemical biology, molecular biology, or biochemistry Experience with cell culture, including maintenance, transfections, stable cell lines, and CRISPR editing Key Attributes
Excellent organization and communication skills, with the ability to prioritize and manage multiple tasks effectively Strong team player and individual contributor, flexible, and capable of delivering high-quality results under tight timelines Pay & Benefits
The base salary range for this position is $105,000 to $120,000, depending on skills, experience, and education. Additional benefits include target bonuses, long-term incentives, 401(k) with company match, and a comprehensive benefits package covering medical, dental, vision, life insurance, and more. EEO & Employment Eligibility
Vividion Therapeutics, Inc. is an Equal Opportunity employer. We consider all qualified applicants regardless of race, color, religion, sex, national origin, age, disability, veteran status, or other protected categories. Privacy Policy
We take your privacy seriously. For details, please review our Privacy Policy at
https://vividion.com/publication/privacy .
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Vividion is a next-generation biotechnology company based in San Diego that leverages its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology enables us to screen, identify, and optimize novel drugs that selectively bind to virtually any protein, including those previously considered “undruggable”. Our pipeline and emerging programs reflect a mature and productive platform capable of delivering first-in-class drugs with novel mechanisms of action such as allosteric inhibitors, protein-protein interaction inhibitors, functional activators, and degraders against undruggable targets in oncology and immunology. We value scientific excellence, creativity, and teamwork. We are committed to ongoing innovation and have fostered a collaborative, dynamic work culture where your ideas and discoveries are valued and impactful. As we grow, opportunities for mentorship and career progression are available. Job Summary
Vividion Therapeutics is seeking a scientist passionate about harnessing proteomics to probe biology and identify new drug targets. The successful candidate will contribute to identifying novel chemical matter and undruggable targets using our state-of-the-art chemical proteomics platform. Responsibilities include performing mass-spectrometry-based proteomics and molecular biology experiments to support discovery, enablement, and pre-clinical projects. Additionally, the candidate will help expand our platform by implementing high-throughput workflows for new chemical probes. Requirements
Experience and Education
Ph.D. (or equivalent experience) in mass-spectrometry based proteomics or chemical biology Experience operating and maintaining orbitrap mass spectrometers and nano-LC systems Proven experience in acquiring, analyzing, and interpreting proteomics datasets (e.g., PRM, TMT, DIA); targeted proteomics experience is a plus Experience preparing samples for MS analysis, including peptide, protein, or PTM enrichment workflows Experience transforming low-throughput assays into robust high-throughput assays Background in chemical biology, molecular biology, or biochemistry Experience with cell culture, including maintenance, transfections, stable cell lines, and CRISPR editing Key Attributes
Excellent organization and communication skills, with the ability to prioritize and manage multiple tasks effectively Strong team player and individual contributor, flexible, and capable of delivering high-quality results under tight timelines Pay & Benefits
The base salary range for this position is $105,000 to $120,000, depending on skills, experience, and education. Additional benefits include target bonuses, long-term incentives, 401(k) with company match, and a comprehensive benefits package covering medical, dental, vision, life insurance, and more. EEO & Employment Eligibility
Vividion Therapeutics, Inc. is an Equal Opportunity employer. We consider all qualified applicants regardless of race, color, religion, sex, national origin, age, disability, veteran status, or other protected categories. Privacy Policy
We take your privacy seriously. For details, please review our Privacy Policy at
https://vividion.com/publication/privacy .
#J-18808-Ljbffr