Senior Associate Scientist-Scientist – Cell Biology and Immunology

Senior Associate Scientist-Scientist – Cell Biology and Immunology

Contract

Cell Biology

Senior Associate Scientist/Scientist – Immunology & Cell Biology

Company Overview:

Prellis Biologics is a dynamic startup revolutionizing the field of immunology and therapeutic development. We are developing next-generation technologies to harness the full potential of the immune system, driving innovation in drug discovery.

Position Overview:

We are seeking a passionate and skilled immunologist to help advance our pioneering in vitro immune system platform. In this high-impact role, you will collaborate with a multidisciplinary team to design and execute high-impact functional assays and contribute directly to the development of novel therapeutic antibodies and T cell receptors (TCRs). This role requires a strong, hands‑on presence in the laboratory.

Key Responsibilities:

• Experimental Design & Execution: Design, execute, and rigorously analyze complex cell‑based experiments aligned with critical research objectives.
• Cell Culture & Aseptic Technique: Isolate, culture, and maintain primary immune cells using strict aseptic techniques.
• Immune Profiling: Perform and analyze multiparameter flow cytometry and cell sorting for comprehensive immune profiling and functional characterization.
• Assay Development & Analysis:
  • Develop, optimize, and execute immune functional assays.
  • Utilize innovative approaches to stimulate and characterize immune cell responses in vitro.
• Scientific Contribution: Contribute deep scientific insight to the design and development of in vitro immune processes and antibody/TCR generation strategies.
• Laboratory Commitment: Maintain a hands‑on presence in the lab (60–80% of the time) in a fast‑paced research environment.
• Compliance & Documentation:
  • Ensure all experimental work strictly complies with established protocols, SOPs, and regulatory standards.
  • Maintain accurate, detailed, and traceable experimental records.
• Analyze, interpret, and present findings at internal meetings and project reviews.
• Actively support troubleshooting, protocol refinement, and continuous improvement initiatives.
• Collaborate effectively with cross‑functional teams to align project goals and share technical expertise.

Qualifications:

• Education: M.S. or Ph.D. in Immunology, Cell Biology, Biotechnology, or a related scientific discipline.
• Experience: 5+ years of relevant laboratory experience in immunology or cell biology (industry experience is highly preferred).
• Core Scientific Knowledge: Strong theoretical and practical understanding of adaptive immunity, particularly B and T cell biology, including cell‑cell interactions and ligand‑receptor signaling pathways.
• Technical Expertise:
  • Proficiency in mammalian cell culture, immune cell isolation, and maintenance.
  • Demonstrated expertise in multiparameter flow cytometry, including panel design, staining, acquisition, and complex data analysis.
  • Experience in antibody development and/or TCR analysis.
  • Experience in antigen‑specific T cell activation.
  • Hands‑on experience with immune functional assays, ELISA, and general protein analysis techniques.
  • Expertise in experimental design, data interpretation, and complex immunological data analysis.
• Professional Skills:
  • Familiarity with laboratory compliance standards, SOPs, and documentation best practices.
  • Strong organizational skills, exceptional attention to detail, and the ability to work effectively both independently and collaboratively.
  • Effective verbal and written communication skills for data reporting and documentation.

Preferred Skills & Experience:

• Knowledge of immune tolerance, vaccine development, or systems immunology.
• Background in protein or sequence bioinformatics.
• Familiarity with molecular biology techniques.
• Skilled in advanced data analysis tools such as FlowJo and GraphPad Prism.
• Prior experience in drug discovery, vaccine, and/or antibody development programs.
• Experience in project management.

Key Attributes:

• Rigor & Compliance: Detail‑oriented with a strong sense of responsibility for scientific rigor, compliance, and thorough documentation.
• Adaptability: Proactive, collaborative, and adaptable in a dynamic, fast‑paced research and startup setting.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth‑oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

$98,000 - $132,000 per year

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