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Open Select

Head of Engineering - Life Sciences

Open Select, New York, New York, us, 10261

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Head of Engineering Location: New York City (On-site)

Salary: Up to $250k + equity

Industry: AI / Life Sciences

What You’ll Drive Join the founding executive team at a venture-backed startup transforming decision‑making in biopharma. With $5.5M in funding, years of runway, and partnerships with top pharma companies, you will work alongside a tight‑knit team building AI‑powered tools that help bring life‑changing therapies to patients faster, all from a collaborative Flatiron office.

As Head of Engineering, you will set the technical vision, drive the product roadmap, and build an elite engineering culture from the ground up. You will blend hands‑on leadership with strategy, own the rollout of innovative AI features, and play a key role in hiring, mentoring, and shaping the future of both the product and the team.

What You’ll Focus On

Define and execute technical and product vision, aligning engineering, product, and business goals

Lead product cycles, deliver new features, and ensure robust, scalable infrastructure

Integrate emerging AI techniques (retrieval, LLMs, agentic AI, RAG systems, vector DBs) and set best practices in architecture, code quality, testing, and DevOps

Recruit, mentor, and manage a high‑performing team, fostering a culture of accountability, curiosity, and collaboration

Represent the company to customers, partners, and investors, and collaborate with leadership on strategic initiatives

Who You Are

6+ years as an engineering leader (Head of Engineering, CTO, founder, tech lead, or engineering manager) with experience hiring, mentoring, and managing early‑stage teams

Led development of user‑centric products with a focus on performance, scalability, and rapid iteration

Hands‑on with React, TypeScript, NodeJS, PostgreSQL, Python, and best practices in architecture, testing, and DevOps

Experienced with advanced AI techniques (agentic AI, RAG systems, multi‑step agents, vector DBs)

Proven track record in fast‑paced, high‑growth, or startup environments, building products from 0 to 1, ideally as part of a small or founding team

High agency and ownership, with a bias for action and delivering high‑quality solutions that improve with feedback

Degree from a top university or equivalent experience, and/or background in high‑caliber technical settings

Strong communicator, comfortable representing technical strategy externally

Tech Stack React, TypeScript, NodeJS, PostgreSQL, Python, LLMs, RAG, agentic AI

Why You’ll Thrive Here

Recently raised $5.5M with 3–4 years of runway, backed by YC, Wireframe Ventures, and Crosslink Capital

Strong early traction with partnerships at top pharma companies and a healthy pipeline for growth

Make a real impact by helping bring drugs to patients faster through transforming how pharma companies make decisions

Founding executive role in a high‑ownership, five‑person team in Flatiron, New York

This role is open to US citizens, Green Card holders and TN visa holders only.

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