Takeda
Director Inflammatory Disease Drug Discovery - Immunology
Takeda, Boston, Massachusetts, us, 02298
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Job Description At Takeda, we are a forward‑looking, world‑class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life‑changing therapies to patients worldwide.
Objective / Purpose The GI‑Drug Discovery Unit at Takeda is a team of experienced, innovative and collaborative drug discovery scientists building an industry‑leading portfolio of drugs for inflammatory and GI diseases with high unmet medical need. We are seeking a leader with significant experience in building and leading biology and cross‑functional drug discovery teams to establish a new group focused on chronic autoimmune diseases.
Position Title Director Inflammatory Drug Discovery
Responsibilities
Develop industry‑leading therapeutics for patients with inflammatory diseases by leading a research group focused on drug development from target identification through to candidate selection.
Recruit, retain, and develop a large team of world‑class, highly innovative in vitro and in vivo research biologists focused on understanding the molecular, cellular and organ‑level drivers of inflammatory disease processes, and identifying and developing drug candidates.
Serve as scientific research thought leader within the Drug Discovery Unit (DDU), working within a highly matrixed environment to build an industry‑leading preclinical and early clinical therapeutic pipeline for inflammatory diseases.
Set discovery portfolio goals for high‑priority autoimmune diseases and ensure alignment with key stakeholders in inflammatory disease research, the clinical development team, and other Takeda stakeholders.
Be accountable for defining the preclinical elements of multiple drug discovery programmes, in partnership with other research leaders across Takeda and the early clinical development team within the GI and Inflammation Therapeutic Area.
Interface with the business development group to identify strategically important innovative external opportunities.
Help maintain the Takeda culture that promotes creativity, open communication, collaboration, collegiality, and a high sense of urgency, while maintaining the highest quality of scientific foundations of the company’s drug discovery process.
Accountabilities
Form a strong partnership with clinical and commercial team colleagues for disease‑area strategic alignment and drive delivery of mid‑long‑term innovative strategies.
Lead early target discovery through candidate selection and partner with the therapeutic area translational team for early development plans.
Partner with the Center for External Innovation at Takeda for the identification and assessment of external platform and pipeline opportunities, providing due diligence and recommendations.
Act as an international subject‑matter expert and global Takeda thought leader in inflammatory disease research, staying up‑to‑date with scientific and competitive developments.
Represent Takeda and foster a presence in the global inflammation and immunology scientific community through meetings.
Encourage diversity and support career development for colleagues and staff.
Ensure all inflammation disease‑area global product teams are resourced for optimal scientific support.
Provide nuanced advice to senior stakeholders on the GI and Inflammation therapeutic landscape.
Leadership
Creative, collaborative, proactive and confident with proven leadership qualities.
Demonstrated ability to work across functions, regions and cultures and adheres to Takeda’s values.
Excellent communicator, able to persuade orally, in presentation and in written format.
Effective team player who builds credibility and confidence internally and externally.
Ability to distil complex issues into simple, comprehensible terms.
Demonstrates leadership presence and confidence.
Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors.
Builds teams across functions and geographies with the right skills and experience.
Invests time in helping others to enhance skills and perform at a higher level.
Represent function in negotiations and resolve conflict constructively.
Interaction
Navigate external and internal dynamics and lead others by creating an inspiring workplace.
Cultivate a broad network of relationships throughout Takeda, with affiliates and external partners.
Build strong relationships and collaborate effectively with other interfacing Takeda functions.
Innovation
Creative scientific thinker with excellent understanding of emerging technologies.
Identify opportunities and anticipate changes in the business landscape through competitive assessment.
Forward‑thinking with the ability to recommend, influence and implement organizational change and continuous innovation.
Take risks implementing innovative solutions, accelerating time to market.
Challenge the status quo and bring forward innovative solutions.
Role model respect and inclusion, creating a culture that fosters innovation.
Education & Competencies (Technical and Behavioral)
Ph.D. in Immunology or closely related discipline with 10+ years drug development experience in highly competitive biopharmaceutical companies.
Or M.S. with 16+ years experience, or B.S. with 18+ years experience.
Expert scientific knowledge in autoimmune and inflammatory disease research with experience in lymphocyte biology is highly desired.
Highly experienced in exploratory drug development with proven biopharmaceutical industry experience leading innovative therapeutic programmes and with expertise in small molecule and/or biologics drug development.
10 years of direct line management and cross‑functional project leadership experience required.
Highly knowledgeable and experienced in all aspects of inflammation disease drug discovery through to candidate selection/IND, including regulatory documentation.
Demonstrated cross‑cultural understanding and ability to manage matrix teams.
Strong leadership skills and acumen.
Excellent written and verbal communication skills in English.
Capable of leading a matrixed team of scientists from within Takeda as well as external collaborators.
Significant experience of participation in business‑development diligence activities in the preclinical discovery function.
Additional Information The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy.
Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
Location Boston, MA
Salary $174,500.00 – $274,230.00
Benefits U.S. based employees may be eligible for short‑term and/or long‑term incentives. They may also participate in medical, dental, vision insurance, a 401(k) plan and company match, short‑term and long‑term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well‑being benefits. U.S. based employees are also eligible to receive up to 80 hours of sick time per calendar year, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Worker Type Employee
Worker Sub‑Type Regular
Time Type Job Exempt: Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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Job Description At Takeda, we are a forward‑looking, world‑class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life‑changing therapies to patients worldwide.
Objective / Purpose The GI‑Drug Discovery Unit at Takeda is a team of experienced, innovative and collaborative drug discovery scientists building an industry‑leading portfolio of drugs for inflammatory and GI diseases with high unmet medical need. We are seeking a leader with significant experience in building and leading biology and cross‑functional drug discovery teams to establish a new group focused on chronic autoimmune diseases.
Position Title Director Inflammatory Drug Discovery
Responsibilities
Develop industry‑leading therapeutics for patients with inflammatory diseases by leading a research group focused on drug development from target identification through to candidate selection.
Recruit, retain, and develop a large team of world‑class, highly innovative in vitro and in vivo research biologists focused on understanding the molecular, cellular and organ‑level drivers of inflammatory disease processes, and identifying and developing drug candidates.
Serve as scientific research thought leader within the Drug Discovery Unit (DDU), working within a highly matrixed environment to build an industry‑leading preclinical and early clinical therapeutic pipeline for inflammatory diseases.
Set discovery portfolio goals for high‑priority autoimmune diseases and ensure alignment with key stakeholders in inflammatory disease research, the clinical development team, and other Takeda stakeholders.
Be accountable for defining the preclinical elements of multiple drug discovery programmes, in partnership with other research leaders across Takeda and the early clinical development team within the GI and Inflammation Therapeutic Area.
Interface with the business development group to identify strategically important innovative external opportunities.
Help maintain the Takeda culture that promotes creativity, open communication, collaboration, collegiality, and a high sense of urgency, while maintaining the highest quality of scientific foundations of the company’s drug discovery process.
Accountabilities
Form a strong partnership with clinical and commercial team colleagues for disease‑area strategic alignment and drive delivery of mid‑long‑term innovative strategies.
Lead early target discovery through candidate selection and partner with the therapeutic area translational team for early development plans.
Partner with the Center for External Innovation at Takeda for the identification and assessment of external platform and pipeline opportunities, providing due diligence and recommendations.
Act as an international subject‑matter expert and global Takeda thought leader in inflammatory disease research, staying up‑to‑date with scientific and competitive developments.
Represent Takeda and foster a presence in the global inflammation and immunology scientific community through meetings.
Encourage diversity and support career development for colleagues and staff.
Ensure all inflammation disease‑area global product teams are resourced for optimal scientific support.
Provide nuanced advice to senior stakeholders on the GI and Inflammation therapeutic landscape.
Leadership
Creative, collaborative, proactive and confident with proven leadership qualities.
Demonstrated ability to work across functions, regions and cultures and adheres to Takeda’s values.
Excellent communicator, able to persuade orally, in presentation and in written format.
Effective team player who builds credibility and confidence internally and externally.
Ability to distil complex issues into simple, comprehensible terms.
Demonstrates leadership presence and confidence.
Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors.
Builds teams across functions and geographies with the right skills and experience.
Invests time in helping others to enhance skills and perform at a higher level.
Represent function in negotiations and resolve conflict constructively.
Interaction
Navigate external and internal dynamics and lead others by creating an inspiring workplace.
Cultivate a broad network of relationships throughout Takeda, with affiliates and external partners.
Build strong relationships and collaborate effectively with other interfacing Takeda functions.
Innovation
Creative scientific thinker with excellent understanding of emerging technologies.
Identify opportunities and anticipate changes in the business landscape through competitive assessment.
Forward‑thinking with the ability to recommend, influence and implement organizational change and continuous innovation.
Take risks implementing innovative solutions, accelerating time to market.
Challenge the status quo and bring forward innovative solutions.
Role model respect and inclusion, creating a culture that fosters innovation.
Education & Competencies (Technical and Behavioral)
Ph.D. in Immunology or closely related discipline with 10+ years drug development experience in highly competitive biopharmaceutical companies.
Or M.S. with 16+ years experience, or B.S. with 18+ years experience.
Expert scientific knowledge in autoimmune and inflammatory disease research with experience in lymphocyte biology is highly desired.
Highly experienced in exploratory drug development with proven biopharmaceutical industry experience leading innovative therapeutic programmes and with expertise in small molecule and/or biologics drug development.
10 years of direct line management and cross‑functional project leadership experience required.
Highly knowledgeable and experienced in all aspects of inflammation disease drug discovery through to candidate selection/IND, including regulatory documentation.
Demonstrated cross‑cultural understanding and ability to manage matrix teams.
Strong leadership skills and acumen.
Excellent written and verbal communication skills in English.
Capable of leading a matrixed team of scientists from within Takeda as well as external collaborators.
Significant experience of participation in business‑development diligence activities in the preclinical discovery function.
Additional Information The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy.
Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
Location Boston, MA
Salary $174,500.00 – $274,230.00
Benefits U.S. based employees may be eligible for short‑term and/or long‑term incentives. They may also participate in medical, dental, vision insurance, a 401(k) plan and company match, short‑term and long‑term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well‑being benefits. U.S. based employees are also eligible to receive up to 80 hours of sick time per calendar year, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Worker Type Employee
Worker Sub‑Type Regular
Time Type Job Exempt: Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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