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Olema Oncology

Senior Director, Business Applications

Olema Oncology, San Francisco, California, United States, 94199

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Olema Oncology is dedicated to developing better medicines for breast cancer and beyond. Our lead program, palazestrant (OP-1250), is a complete estrogen receptor antagonist (CERAN) currently in development for metastatic breast cancer with blockbuster potential as a monotherapy and in combination in ER+/HER2- metastatic breast cancer. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with best-in-class potential. Our scientific breakthroughs are accelerated through the ways in which we fearlessly support, motivate, and challenge one another. At Olema, we know that when we put people first, our work becomes second to none. If you’re ready to join us at the edge of something unstoppable, let’s make a profound impact together for

our patients, for your career, for what’s beyond . You can view our latest corporate deck and other presentations here . About the Role: Senior Director, Business Applications

As theSenior Director,Business Applications,reporting to theVice President, Information Technology,you area seasoned and visionary Senior Director who will oversee andoptimizeall General & Administrative (G&A) business systems. You will lead a high-impact team in enhancing, hardening, and scaling enterprise systems to support Olema’s transition toward commercialization and sustained growth. This is a unique opportunity to make a meaningful impactata dynamic biotech company during a pivotal phase in its development. This role is based in either our San Francisco or Boston office and will require 10%travel. Your work will primarily encompass: Responsibilities

Own the strategic roadmap, budget and day-to-day management of G&A business systems including NetSuite, Prendio, Agiloft, BambooHR, Greenhouse, and Culture Amp Hardening existing systems to prepare for commercialization and ensure enterprise scalability, audit readiness, and compliance with SOX (404A & B) requirements Partner with Finance, HR, Legal, Procurement, Talent, Facilities and IT teams to understand evolving business requirements and deliver efficient, scalable solutions Ensure successful adoption of new technologies and enhancements through structured change management practices, including communication, training, and stakeholder alignment Evaluate and implement AI-driven tools and automation platforms, and workflow optimization solutions – such as Workato or similar iPaas technologies - to improve business performance and operational efficiency Drive continuous improvement and digital transformation efforts by identifying opportunities for process redesign, automation and integration across systems Ensure application governance, data integrity, system security, and adherence to internal controls and SOX processes Lead system and vendor evaluations, platform assessments, and RFP processes to achieve the optimal technical fit and value for the organization Manage vendor relationships and contract negotiations for SaaS platforms and service providers Provide oversight and partnership with R&D teams (~10–15% of your time) to support scientific applications, data workflows, and system integrations that enable research innovation Mentor and grow a high-performing Business Applications team aligned with Olema’s culture and mission Ideal Candidate Profile

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. Allemployeeswithin our company play aunique andcrucial rolein our success, both inaccomplishingour mission and buildinga positivecompany culture. As such, we are looking forsomeone withthe right combination of knowledge, experience, and attributes for this role. Knowledge

Bachelor's degree in information systems, computer science, or related discipline; advanced degree preferred Strong knowledge of AI technologies, data management, and automation tools to drive digital transformation Demonstrated leadership in managing cross-functional teams and complex system implementations Proven success scaling and hardening systems in preparation for commercialization Demonstrated ability to translate business requirements into technical solutions and architect scalable, future-ready systems Experience

A minimum of10+ years of experience managing enterprise applications, with a strong background in G&A systems within the biotech or pharmaceutical industry A minimum of 5+ years of experience building, leading, managing, developing and mentoring direct reports Hands-on experience with NetSuite is a must. Prendio, Agiloft, BambooHR, Greenhouse, and Culture Amp, Workato or similar tools highly preferred Track record of process optimization, workflow automation, and driving operational efficiency Experience working within or preparing organizations for SOX compliance, including system controls, audit requirements, and governance Proven success in system and vendor selection, including leading evaluations, RFPs, and contract negotiations Attributes

Exceptional communication skills and the ability to influence stakeholders at all levels of the organization Strong commitment to excellence and delivering outstanding user experiences Highly analytical and data-driven decision-maker Proactive, self-motivated, and results-oriented with a "bias for action" Collaborative team player who thrives in a cross-functional environment Flexible and adaptable to evolving business needs and technology trends Compensation

The base pay range for this position is expected to be

$270,000 - $290,000

annually; however, the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits. Equal Opportunity and EEO Statement

We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated. Benefits

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. Fraud Alert

We are aware of employment scams where individuals pose as representatives of Olema Oncologyand make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is olev.com ; our careers page isolema.com/careers ; our LinkedIn page islinkedin.com/company/olema-oncology .Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront paymentsof any kind, and does not make job offers without an in-person interview.

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