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Enigma Search

Senior Medical Director (Neurology & Early Development)

Enigma Search, South San Francisco, California, us, 94083

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Senior Medical Director (Neurology & Early Development)

Base pay range:

$340,000.00/yr - $400,000.00/yr Additional compensation:

Annual Bonus Our client is seeking a

Medical Director or Senior Medical Director

to lead their

Neurological and Neuropsychiatric

clinical portfolio. This is a high-impact role reporting directly to the Head of Clinical Sciences. You will be the clinical architect for programs moving from preclinical discovery into human ‘Proof-of-Mechanism’ and ‘Proof-of-Concept’ trials. The Impact You Will Make

Strategic Leadership:

Lead high-performing cross-functional teams to translate preclinical data into robust human clinical strategies and biomarker development. Experimental Medicine:

Design and execute innovative ‘Phase 0’ through Phase 2 studies to demonstrate proof-of-mechanism for novel targets in the neuropsychiatric space. Collaborative Discovery:

Act as a key interface between research and drug development, working closely with discovery scientists and external partners to shape disease indication strategies. Clinical Expertise:

Utilize your medical background to guide the development of preclinical models and ensure they align with human clinical needs. Regulatory & Scientific Content:

Author and provide expert medical oversight for protocols, Investigator Brochures (IBs), Clinical Study Reports (CSRs), and regulatory submissions. Who You Are

Physician-Scientist:

You hold an M.D. or an M.D./Ph.D. with a deep scientific mindset. Neurology Expert:

Board certification or eligibility in

Neurology or Pediatric Neurology

is highly preferred. Proven Industry Veteran:

You have 5+ years of translational or clinical drug development experience within biotech, pharma, or a top-tier academic research setting. Early Phase Specialist:

You possess direct experience or a deep working knowledge of early clinical trial methodology (Phase 0, 1, and 2). Collaborative Leader:

You excel in a matrixed environment, possessing the ability to lead through influence and bring out the best in cross-functional teams. Why This Role?

This is not a traditional ‘late-stage’ medical monitoring role. This is a position for a scientist-clinician who wants to be at the forefront of

Early Development (Translational) , working on novel targets that have the potential to redefine how we treat neurological diseases. Seniority Level

Director Employment Type

Full-time Job Function

Research and Science Benefits

Medical insurance Vision insurance 401(k)

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