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Astrix

Bioinformatics Scientist

Astrix, California, Missouri, United States, 65018

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Bioinformatics / Machine Learning Scientist (Contract) Location:

Remote (must be available during Pacific Time business hours)

Contract Type:

1‑year contract with possibility of extension

Start Date:

ASAP

Department:

Computational Biology & Medicine

Pay Rate:

$50–$66/hour (flexible for exceptional candidates) + Benefits

Position Overview We are seeking a highly motivated Bioinformatics / Machine Learning Scientist to join the Computational Biology & Medicine team within the Computational Sciences Center of Excellence. This role will support a high‑impact project focused on developing predictive machine learning models to assess patient risk for drug‑induced liver toxicity.

The successful candidate will play a key role in data harmonization, feature engineering, and advanced modeling, integrating diverse clinical and biological datasets to identify predictive signatures that distinguish at‑risk and not‑at‑risk patient populations.

Key Responsibilities

Centralize, curate, and harmonize multimodal datasets including clinical, genetic, omics, and safety laboratory data

Engineer and derive meaningful features from structured and unstructured data sources

Apply advanced machine learning and statistical modeling techniques to predict patient risk for drug‑induced liver toxicity

Perform survival analysis and other relevant statistical methods as part of model development

Required Qualifications

PhD

in a quantitative discipline such as Computer Science, Computational Biology, Machine Learning, Bioinformatics, Statistics, or Mathematics

Strong expertise in

Python and/or R

for data manipulation, statistical analysis, and machine learning model development

Proven experience applying statistical modeling and machine learning methods to complex biological datasets

Demonstrated ability to work with and integrate diverse data types, such as

omics, clinical, imaging, and safety data

Solid understanding of statistics, including

survival analysis

Domain Expertise

Demonstrated interest in biological problems related to

drug discovery and development

Experience contributing to scientific research, including a

strong publication record

Must be authorized to work in the United States without sponsorship

Preferred Qualifications

Experience using

NLP and Large Language Models (LLMs)

for feature extraction from unstructured text

Background in

neuroscience

Experience working in pharmaceutical or biomedical research environments

Seniority level Mid‑Senior level

Employment type Full‑time

Job function Science

Industries IT Services and IT Consulting

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