POSTDOCTORAL RESEARCHER - Genetics Host Defense - Zhang Lab

A postdoctoral training position is available in the laboratory of Dr. Zhao Zhang, in the Center for the Genetics of Host Defense at UT Southwestern Medical Center to study molecular mechanisms of metabolic diseases. The Zhang laboratory combines a unique mouse forward genetic screening approach with biochemistry and molecular biology to identify new regulators of major metabolic diseases, including obesity, diabetes, and metabolic dysfunction-associated steatotic liver disease (MASLD). Since the lab’s establishment in 2020, our work has led to publications in prestigious journals including Science, Cell Metabolism, PNAS, Nature Communications, Journal of Clinical Investigation, Cell Death and Differentiation, Circulation (accepted), and Nature Communications (accepted). Our laboratory has several exciting projects related to: 1) The dynamic regulation of a newly identified E3 ubiquitin ligase in insulin signaling. 2) The role of several new genes in the regulation of obesity. 3) The mechanism of several new genes in the pathogenesis of MASLD. The research in our laboratory is funded by multiple NIH grants. Candidates must hold a recent Ph.D. and/or M.D. degree. Experience in cell signaling, mouse genetics, fatty liver disease, obesity, and diabetes research leading to publication in peer-reviewed journals is recommended. Information can be found at http://www.utsouthwestern.edu/postdocs. Interested individuals should send a CV, statement of interests, and a list of three references to Zhao Zhang (Zhao.Zhang@UTSouthwestern.edu). UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule. To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/. Benefits

PPO medical plan, available day one at no cost for full-time employee-only coverage 100% coverage for preventive healthcare – no copay Paid Time Off, available day one Retirement Programs through the Teacher Retirement System of Texas (TRS) Paid Parental Leave Benefit Wellness programs Tuition Reimbursement Public Service Loan Forgiveness (PSLF) Qualified Employer Learn more about these and other UTSW employee benefits!

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