Johnson Service Group
Johnson Service Group (JSG) is currently looking for a Scientist to execute high-throughput cell-based assays in 384-well format. You will culture and plate cells, dispense compounds using the Echo, run diverse detection readouts, and analyze dose–response data to deliver high-quality EC50 results for discovery programs. This is a contract role with a global leader in pharmaceutical products in Rahway NJ. Pay $53.45/hour Requirements: BS/MS/PHD in Biology, Pharmacology, Biochemistry, or related field; BS with 5+ years, Masters with 3+ years and PHD with 1+ year of industry or equivalent lab experience. Proficiency in mammalian cell culture and 384-well assay workflows Experience with plate readers and assay platforms (e.g., cAMP, HTRF, luminescent assays) Strong data analysis skills: 4PL curve fitting, EC50/IC50 determination, and curve QC (e.g., R^2, top/bottom constraints) Detail-oriented, organized, and comfortable in a fast-paced, high-throughput environment Nice to Have: Experience with automation/LIQ handlers, LIMS/ELN, and statistical QC (Z’, CV, S/B) Familiarity with GraphPad Prism, ActivityBase, or equivalent analysis tools Hands-on experience with Echo acoustic dispensing. Key Responsibilities: Maintain, expand, and plate mammalian cell lines for 384-well assays Set up and execute assays with compound dispensing via Labcyte/Beckman Echo Run and optimize detection formats (e.g., luminescence, cAMP, HTRF/TR-FRET, fluorescence) Generate dose–response curves (4-parameter logistic fits) and report EC50/IC50 with QC Troubleshoot assay performance, optimize Z’ factors, and document SOPs/results Collaborate with discovery teams to prioritize studies and timelines Additional responsibilities may include setting up western blot assays and learning how to run in-cell westerns Johnson Service Group, Inc. (JSG) is a North American leader in the staffing and consulting services industry, with over 35 years of experience investing in people and companies. Johnson Service Group (JSG) is an Equal Opportunity Employer. JSG provides equal employment opportunities to all applicants and employees without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, marital status, protected veteran status, or any other characteristic protected by law. Allen Mudalel (610) 828-7356 amudalel@jsginc.com 515 Grove St. Suite 3G • Haddon Heights, NJ 08035 • jsginc.com