Mount Sinai Morningside
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Description
Job Description
Dept. Dermatology
Title:
Post Doc Fellow
Physical work location:
787 11th Avenue, 6th Floor, New York, NY 10019
Name PI or Supervisor:
Dr. Hongzhen Hu (E: hongzhen.hu@mssm.edu)
Web link to Lab:
https://icahn.mssm.edu/about/departments/dermatology
Web link to Dep’:
https://icahn.mssm.edu/about/departments/dermatology
Administrative Contact:
Pam Gassner (E: Pamela.Gassner@mountsinai.org)
Responsibilities
Details of Research Project: The Post Doc Fellow will work on pilot studies investigating how CGRP‑expressing trigeminal sensory neurons communicate with immune cells in the meninges. They will use genetic models to stimulate or inhibit the CGRP‑expressing trigeminal sensory neurons to perform gain and loss of function studies. They will also use reporter mice to trace nerve fibers of these neurons in young and aged mice to see if aging impacts the structure and function of these neurons and its impact on neuroimmune crosstalk in the meninges.
Technical Duties
Designing and executing scientific experiments
Regular presentation of data in lab meetings, work‑in‑progress, seminars, and national/international meetings
Provides data for grant submissions and progress reports for NIH and foundations
Attending meetings or taking part in conference calls with other clinicians and scientists
Analyzes and interprets research results and the scientific literature in connection with writing or editing high‑quality grant fellowship applications, manuscripts, etc.
Helps other researchers translate data results into a manuscript format and propel them to publication
Effectively manages time, multi‑task, and handle a high volume of work in a fast‑paced environment.
Develops detailed project timelines according to team and project‑specified deadlines
Supervises technicians, graduate students, and junior postdoctoral fellows
Other relevant duties as needed
Qualifications
Educational and other Requirements for the position: MD and/or PhD degree, and applicable experience and education.
Experience Required: 3+ years of relevant experience in laboratory. Specific skillsets required: basic flow cytometry, preparation of RNA, quantitative real‑time PCR, RNA‑seq, in vivo mouse work, basic staining and prep for imaging. Desired skillsets: single‑cell bioinformatics experience, epigenomics background, calcium imaging.
Goals/Outcomes Of The Research Project
Knowledge of the underlying mechanisms of migraine and headache will lead to new rational‑based treatment approaches by electively targeting specific pain signaling pathways in the trigeminal system.
Employer Description
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees across multiple hospitals, outpatient practices, and laboratories. The system is committed to advancing health through research, education, and patient care.
Equal Opportunity Employer
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law.
Compensation
The salary range for the role is $72,500–$80,000 annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses, differential pay, or other forms of compensation or benefits.
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Description
Job Description
Dept. Dermatology
Title:
Post Doc Fellow
Physical work location:
787 11th Avenue, 6th Floor, New York, NY 10019
Name PI or Supervisor:
Dr. Hongzhen Hu (E: hongzhen.hu@mssm.edu)
Web link to Lab:
https://icahn.mssm.edu/about/departments/dermatology
Web link to Dep’:
https://icahn.mssm.edu/about/departments/dermatology
Administrative Contact:
Pam Gassner (E: Pamela.Gassner@mountsinai.org)
Responsibilities
Details of Research Project: The Post Doc Fellow will work on pilot studies investigating how CGRP‑expressing trigeminal sensory neurons communicate with immune cells in the meninges. They will use genetic models to stimulate or inhibit the CGRP‑expressing trigeminal sensory neurons to perform gain and loss of function studies. They will also use reporter mice to trace nerve fibers of these neurons in young and aged mice to see if aging impacts the structure and function of these neurons and its impact on neuroimmune crosstalk in the meninges.
Technical Duties
Designing and executing scientific experiments
Regular presentation of data in lab meetings, work‑in‑progress, seminars, and national/international meetings
Provides data for grant submissions and progress reports for NIH and foundations
Attending meetings or taking part in conference calls with other clinicians and scientists
Analyzes and interprets research results and the scientific literature in connection with writing or editing high‑quality grant fellowship applications, manuscripts, etc.
Helps other researchers translate data results into a manuscript format and propel them to publication
Effectively manages time, multi‑task, and handle a high volume of work in a fast‑paced environment.
Develops detailed project timelines according to team and project‑specified deadlines
Supervises technicians, graduate students, and junior postdoctoral fellows
Other relevant duties as needed
Qualifications
Educational and other Requirements for the position: MD and/or PhD degree, and applicable experience and education.
Experience Required: 3+ years of relevant experience in laboratory. Specific skillsets required: basic flow cytometry, preparation of RNA, quantitative real‑time PCR, RNA‑seq, in vivo mouse work, basic staining and prep for imaging. Desired skillsets: single‑cell bioinformatics experience, epigenomics background, calcium imaging.
Goals/Outcomes Of The Research Project
Knowledge of the underlying mechanisms of migraine and headache will lead to new rational‑based treatment approaches by electively targeting specific pain signaling pathways in the trigeminal system.
Employer Description
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees across multiple hospitals, outpatient practices, and laboratories. The system is committed to advancing health through research, education, and patient care.
Equal Opportunity Employer
The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law.
Compensation
The salary range for the role is $72,500–$80,000 annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses, differential pay, or other forms of compensation or benefits.
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