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Mount Sinai Health System

Postdoctoral Fellow-MSH-12720-034

Mount Sinai Health System, New York, New York, us, 10261

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Description Dept. Dermatology

Title Post Doc Fellow

Physical work location 787 11th Avenue, 6th Floor, New York, NY 10019

Name PI or Supervisor Dr. Hongzhen Hu, E: hongzhen.hu@mssm.edu

Web link to Lab https://icahn.mssm.edu/about/departments/dermatology

Web link to Department https://icahn.mssm.edu/about/departments/dermatology

Administrative Contact Pam Gassner, E: Pamela.Gassner@mountsinai.org

Responsibilities Details of Research Project: The Post Doc Fellow will work on pilot studies investigating how CGRP‑expressing trigeminal sensory neurons communicate with immune cells in the meninges. They will use genetic models to stimulate or inhibit the CGRP‑expressing trigeminal sensory neurons to perform gain and loss of function studies. They will also use reporter mice to trace nerve fibers of these neurons in young and aged mice to see if aging impacts the structure and function of these neurons and its impact on neuroimmune crosstalk in the meninges.

Technical Duties

Designing and executing scientific experiments

Regular presentation of data in lab meetings, work‑in‑progress, seminars, and national/international meetings

Provides data for grant submissions and progress reports for NIH and foundations

Attending meetings or taking part in conference calls with other clinicians and scientists

Analyzes and interprets research results and the scientific literature in connection with writing or editing high‑quality grant fellowship applications, manuscripts, etc.

Helps other researchers translate data results into a manuscript format and propel them to publication

Effectively manages time, multi‑task, and handles a high volume of work in a fast‑paced environment

Develops detailed project timelines according to team and project‑specified deadlines

Supervises technicians, graduate students, and junior postdoctoral fellows

Other relevant duties as needed

Qualifications Educational and other Requirements for the position:

MD and/or PhD degree, and applicable experience and education

Experience Required:

3+ years of relevant experience in laboratory. Specific skillsets required: basic flow cytometry, preparation of RNA, quantitative real‑time PCR, RNA‑seq, in vivo mouse work, basic staining and prep for imaging. Desired skillsets: single‑cell bioinformatics experience, epigenomics background, calcium imaging.

Goals/Outcomes of the Research Project Knowledge of the underlying mechanisms of migraine and headache will lead to new rational‑based treatment approaches by electively targeting specific pain signaling pathways in the trigeminal system.

Employer Description The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care and to creating a culture of inclusion, respect, and continuous learning.

Equal Opportunity Employer The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law.

Compensation The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72,500 - $80,000 annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses, incentive pay, differential pay, or other forms of compensation or benefits.

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