Dana-Farber Cancer Institute
Postdoctoral Research Fellow - Wolpin-Nowak Lab
Dana-Farber Cancer Institute, Boston, Massachusetts, us, 02298
The Dana‑Farber Cancer Institute seeks a Research Fellow to focus on next‑generation translational pathology studies in the Wolpin‑Nowak laboratory (https://labs.dana‑farber.org/wolpin‑nowaklab/), as part of the Hale Family Center for Pancreatic Cancer Research (https://labs.dana‑farber.org/halecenter) and the Lustgarten Foundation Pancreatic Cancer Research Laboratory at Dana‑Farber.
Our research group investigates the biology and risk factors associated with pancreatic and other gastrointestinal cancers, aiming to improve patient outcomes both by identifying cancer earlier and by improving therapy. We learn from cancer patients by studying human biospecimens so that discoveries can be rapidly translated into improved clinical care.
Our laboratory members include epidemiologists, biostatisticians, pathologists, data scientists, molecular biologists, and clinical researchers, all contributing unique expertise to our work. We employ a broad variety of approaches and techniques including population‑scale epidemiology studies, digital pathology, genomic sequencing, and spatial transcriptomic and protein profiling. Our tissue profiling incorporates both clinical trial correlative studies and landscape‑directed discovery studies. We work closely with the Gastrointestinal Cancer Center Biobank to acquire samples from Dana‑Farber patients and routinely collaborate nationally to study pancreatic cancer using model systems and lead clinical trials.
Located in Boston and surrounding communities, Dana‑Farber is a leader in cancer research and patient care, united by a mission to conquer cancer, HIV/AIDS, and related diseases. We create an inclusive, diverse, and equitable environment, providing compassionate care to patients of all backgrounds and promoting public health among high‑risk and underserved populations.
At Dana‑Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. If working in this organization inspires you, we encourage you to apply.
Responsibilities
Design and conduct studies using multiplex immunofluorescence, spatial transcriptional profiling, and other cutting‑edge, high‑dimensional tissue analysis approaches to evaluate pancreatic cancer pathology using human tissue specimens
Assemble analysis pipelines using machine learning to process tissue data reproducibly and at scale
Conduct analyses using programming languages such as R and Python
Collaborate with other laboratory members with expertise in epidemiology, bioinformatics, pathology, molecular biology, and functional genomics
Participate in group meetings and work collaboratively on larger projects with other group members
Lead projects that result in first‑author manuscripts
Write grants and progress reports related to research funding
Qualifications
Candidates should hold a doctoral degree in genetics/genomics, cancer biology, pathology or related fields.
Multidisciplinary training and experience in multiple of these fields is desirable.
MD or MD‑equivalent and PhD‑holding candidates will both be considered; MD/PhD‑holding candidates with pathology training are highly encouraged to apply.
Knowledge, Skills, and Abilities
Strong background in human pathology
Experience with traditional pathology laboratory techniques, including slide sectioning, H&E staining, immunohistochemistry and special stains a plus
Experience with translational pathology techniques, including multiplexed immunofluorescence, spatial transcriptomics, and RNA in situ hybridization a plus
Experience with digital image analysis platforms (Halo, VisioPharm, QuPath, InForm, etc.) a plus
Experience with R, Python, and commonly used libraries/packages a plus
Enthusiasm for novel assay and technology development
Ability to independently analyze information and troubleshoot when required
Excellent written and verbal communication skills
Attention to detail and thoroughness in completing work tasks
Ability to work within a team environment
Adaptability to a fast‑paced, dynamic environment
EEO Poster Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$72,000.00 - $76,385.00
Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
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Our research group investigates the biology and risk factors associated with pancreatic and other gastrointestinal cancers, aiming to improve patient outcomes both by identifying cancer earlier and by improving therapy. We learn from cancer patients by studying human biospecimens so that discoveries can be rapidly translated into improved clinical care.
Our laboratory members include epidemiologists, biostatisticians, pathologists, data scientists, molecular biologists, and clinical researchers, all contributing unique expertise to our work. We employ a broad variety of approaches and techniques including population‑scale epidemiology studies, digital pathology, genomic sequencing, and spatial transcriptomic and protein profiling. Our tissue profiling incorporates both clinical trial correlative studies and landscape‑directed discovery studies. We work closely with the Gastrointestinal Cancer Center Biobank to acquire samples from Dana‑Farber patients and routinely collaborate nationally to study pancreatic cancer using model systems and lead clinical trials.
Located in Boston and surrounding communities, Dana‑Farber is a leader in cancer research and patient care, united by a mission to conquer cancer, HIV/AIDS, and related diseases. We create an inclusive, diverse, and equitable environment, providing compassionate care to patients of all backgrounds and promoting public health among high‑risk and underserved populations.
At Dana‑Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. If working in this organization inspires you, we encourage you to apply.
Responsibilities
Design and conduct studies using multiplex immunofluorescence, spatial transcriptional profiling, and other cutting‑edge, high‑dimensional tissue analysis approaches to evaluate pancreatic cancer pathology using human tissue specimens
Assemble analysis pipelines using machine learning to process tissue data reproducibly and at scale
Conduct analyses using programming languages such as R and Python
Collaborate with other laboratory members with expertise in epidemiology, bioinformatics, pathology, molecular biology, and functional genomics
Participate in group meetings and work collaboratively on larger projects with other group members
Lead projects that result in first‑author manuscripts
Write grants and progress reports related to research funding
Qualifications
Candidates should hold a doctoral degree in genetics/genomics, cancer biology, pathology or related fields.
Multidisciplinary training and experience in multiple of these fields is desirable.
MD or MD‑equivalent and PhD‑holding candidates will both be considered; MD/PhD‑holding candidates with pathology training are highly encouraged to apply.
Knowledge, Skills, and Abilities
Strong background in human pathology
Experience with traditional pathology laboratory techniques, including slide sectioning, H&E staining, immunohistochemistry and special stains a plus
Experience with translational pathology techniques, including multiplexed immunofluorescence, spatial transcriptomics, and RNA in situ hybridization a plus
Experience with digital image analysis platforms (Halo, VisioPharm, QuPath, InForm, etc.) a plus
Experience with R, Python, and commonly used libraries/packages a plus
Enthusiasm for novel assay and technology development
Ability to independently analyze information and troubleshoot when required
Excellent written and verbal communication skills
Attention to detail and thoroughness in completing work tasks
Ability to work within a team environment
Adaptability to a fast‑paced, dynamic environment
EEO Poster Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$72,000.00 - $76,385.00
Dana‑Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
#J-18808-Ljbffr