Septerna, Inc.
Research Associate, In Vivo Pharmacology
Septerna, Inc., South San Francisco, California, us, 94083
Septerna – Research Associate – South San Francisco, CA
Septerna is a biotechnology company focused on developing life‑changing medicines through GPCR‑focused drug discovery. Our Native Complex Platform™ recapitulates GPCRs with native structure, function, and dynamics outside the cellular context to enable novel access to structural and screening technologies at industrial scale.
We are expanding a multidisciplinary team of drug hunters, scientists, and business professionals. Diversity of thought, expertise, and background is central to collaboration and innovation. Brown teams bring life‑changing medicines to patients.
Responsibilities
Design and execute in vivo pharmacology studies to understand therapeutic mechanism in relevant disease models.
Generate, analyze, document, and help interpret data to establish functional PK/PD relationships.
Work collaboratively with in vivo, in vitro, and ex vivo models to determine the mechanism of action of drug candidates.
Be a member of multiple project teams and present results in lab, team, and department meetings.
Perform literature searches, read and interpret papers to help design and trouble‑shoot in vivo, ex vivo and in vitro experiments.
Help author in vivo pharmacology study designs, protocols, and reports to support regulatory filings.
Follow all company policies/practices, and maintain accurate records and notebooks.
Required Education, Skills & Experience
BSc in Pharmacology, Toxicology, or related biological science.
1–3 years of direct hands‑on experience with in vivo studies or disease models in academia or the biotechnology or pharmaceutical industries.
Ability to work directly with rodent models for dosing (PO, SC, IP, IV) and blood collection.
Experience working with other scientists to analyze, interpret, and present data.
Ability to collaborate in writing protocols and trouble‑shooter biological experiments.
Detail‑oriented and organized, with strong interpersonal skills for clear and effective communication – proactive engagement with colleagues.
Preferred Skills & Experience
Experience working with primary cells or ex vivo models.
Experience working with the generation of surgical models in rodents (e.g., osmotic minipump implantation or stereotaxic surgery).
Previous work on therapeutic discovery and development programs in the field of endocrine and metabolic diseases.
Experience working with vendors and CROs to execute studies, analyze data, and generate reports.
ELN experience with Benchling and data analysis with GraphPad Prism.
Title commensurate with experience.
Anticipated salary range (South San Francisco, CA): $70,000 – $85,000.
Septerna’s compensation package includes benefits, stock options, and an annual target bonus for full‑time positions.
Equal Opportunity Employer
– We are an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Septerna participates in the E‑Verify program.
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We are expanding a multidisciplinary team of drug hunters, scientists, and business professionals. Diversity of thought, expertise, and background is central to collaboration and innovation. Brown teams bring life‑changing medicines to patients.
Responsibilities
Design and execute in vivo pharmacology studies to understand therapeutic mechanism in relevant disease models.
Generate, analyze, document, and help interpret data to establish functional PK/PD relationships.
Work collaboratively with in vivo, in vitro, and ex vivo models to determine the mechanism of action of drug candidates.
Be a member of multiple project teams and present results in lab, team, and department meetings.
Perform literature searches, read and interpret papers to help design and trouble‑shoot in vivo, ex vivo and in vitro experiments.
Help author in vivo pharmacology study designs, protocols, and reports to support regulatory filings.
Follow all company policies/practices, and maintain accurate records and notebooks.
Required Education, Skills & Experience
BSc in Pharmacology, Toxicology, or related biological science.
1–3 years of direct hands‑on experience with in vivo studies or disease models in academia or the biotechnology or pharmaceutical industries.
Ability to work directly with rodent models for dosing (PO, SC, IP, IV) and blood collection.
Experience working with other scientists to analyze, interpret, and present data.
Ability to collaborate in writing protocols and trouble‑shooter biological experiments.
Detail‑oriented and organized, with strong interpersonal skills for clear and effective communication – proactive engagement with colleagues.
Preferred Skills & Experience
Experience working with primary cells or ex vivo models.
Experience working with the generation of surgical models in rodents (e.g., osmotic minipump implantation or stereotaxic surgery).
Previous work on therapeutic discovery and development programs in the field of endocrine and metabolic diseases.
Experience working with vendors and CROs to execute studies, analyze data, and generate reports.
ELN experience with Benchling and data analysis with GraphPad Prism.
Title commensurate with experience.
Anticipated salary range (South San Francisco, CA): $70,000 – $85,000.
Septerna’s compensation package includes benefits, stock options, and an annual target bonus for full‑time positions.
Equal Opportunity Employer
– We are an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Septerna participates in the E‑Verify program.
#J-18808-Ljbffr