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Oak Ridge Institute for Science and Education

USDA-ARS Biochemistry Fellowship for Protein Purification

Oak Ridge Institute for Science and Education, Manhattan, Kansas, United States, 66506

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USDA-ARS Biochemistry Fellowship for Protein Purification

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Oak Ridge Institute for Science and Education .

Organization U.S. Department of Agriculture (USDA) - Agricultural Research Service (ARS), located in Manhattan, Kansas.

Reference Code USDA-ARS-PA-2026-0004

Application Deadline 3/13/2026 3:00:00 PM Eastern Time Zone

Description The Biologics Development Module (BDM) is a state‑of‑the‑art applied research laboratory space within the National Bio and Agro‑Defense Facility (NBAF) operating at BSL‑2. The BDM partners with USDA researchers to develop new vaccine candidates for veterinary viruses. The fellowship will focus on purification of antibodies, antigens, and other proteins integral to vaccine development.

Learning Objectives

Prepare culture supernatants and cell lysate samples for purification by ultrafiltration, dialysis, diafiltration, and protein precipitation.

Set up, develop, and optimize protein purification methods using chromatography equipment.

Purify protein samples using immunoaffinity, metal affinity, size exclusion, and/or ion exchange chromatography methods.

Further process and characterize purified protein samples by ultrafiltration, diafiltration, and spectrophotometric methods.

Conjugate proteins on solid support or with fluorescent molecules.

Collect and maintain data in a laboratory notebook.

Collaborate with cross‑disciplinary teams to support the project goals.

Mentor Teshome Aboye (teshome.aboye@usda.gov)

Appointment Details

Start Date: Early 2026 (flexible depending on factors)

Length: Initial one year, may be renewed based on funding.

Full‑time participation.

Monthly stipend: $55,897 – $105,384 annually (commensurate with educational level and experience).

Citizenship: U.S. citizen only.

Eligibility Requirements

Currently pursuing or have received a master’s or doctoral degree in Chemistry, Materials Sciences, Life Health and Medical Sciences, Mathematics, or Statistics.

Experience in a Biosafety Level 2 (BSL‑2) laboratory recommended.

Experience with protein separation, chromatography, and protein expression desired.

Solid background in chemical safety beneficial.

Questions Visit the program website or email ORISE.ARS.Plains@orau.org with the reference code.

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