The University of Texas Southwestern Medical Center
POSTDOCTORAL RESEARCHER - Simmons Comprehensive Cancer Center - Chiang Lab
The University of Texas Southwestern Medical Center, Dallas, Texas, United States, 75215
Postdoctoral Fellow in Transcription, Chromatin, Epigenetics, HPV, Molecular Virology, Cancer Biology, and Small Molecule Inhibitors
Research Area:
Molecular Virology, Cancer Biology, Transcription, Chromatin, Gene Regulation, Epigenetic Control, and Posttranslational Modification
A postdoctoral training position is available in the laboratory of Dr. Cheng-Ming Chiang, PhD (https://profiles.utsouthwestern.edu/profile/95126/cheng-ming-chiang.html) in the Simmons Comprehensive Cancer Center at UT Southwestern Medical Center to study breast cancer, human papillomavirus (HPV), mechanism of chromatin-dependent transcription, posttranslational modification of transcription factors, cofactors and the general transcription machinery, cancer biology, and small compound development.
Our current interest is to understand the molecular basis of the epigenetic reader protein BRD4 in transcription programming, DNA repair, and cancer pathway selectivity, and further develop small molecule inhibitors to block the oncogenic function of BRD4 using biochemical, molecular, genetic, chemical biology, and genomic approaches with in vitro‑reconstituted chromatin transcription, cell‑based, and inducible knockout and knock‑in transgenic mouse disease models. Breast cancer and HPV are two disease models presently pursued in the lab.
Applicants with a recent Ph.D. degree and a strong background in transcription, chromatin, protein biochemistry, molecular biology, virology, chemical biology, mouse models, genomics, and proteomics are encouraged to apply. Expertise in animal work is preferred but not essential.
Information on our postdoctoral training program, benefits, and a virtual tour can be found at http://www.utsouthwestern.edu/postdocs.
Interested individuals should send a CV, statement of interests, and a list of three references to:
Cheng‑Ming Chiang, PhD.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, Texas 75390-8807
cheng-ming.chiang@utsouthwestern.edu
https://labs.utsouthwestern.edu/chiang-lab
UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
This position is security‑sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full‑time schedule.
To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/
Benefits UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
PPO medical plan, available day one at no cost for full‑time employee‑only coverage
100% coverage for preventive healthcare – no copay
Paid Time Off, available day one
Retirement Programs through the Teacher Retirement System of Texas (TRS)
Paid Parental Leave Benefit
Wellness programs
Tuition Reimbursement
Public Service Loan Forgiveness (PSLF) Qualified Employer
Learn more about these and other UTSW employee benefits!
#J-18808-Ljbffr
Research Area:
Molecular Virology, Cancer Biology, Transcription, Chromatin, Gene Regulation, Epigenetic Control, and Posttranslational Modification
A postdoctoral training position is available in the laboratory of Dr. Cheng-Ming Chiang, PhD (https://profiles.utsouthwestern.edu/profile/95126/cheng-ming-chiang.html) in the Simmons Comprehensive Cancer Center at UT Southwestern Medical Center to study breast cancer, human papillomavirus (HPV), mechanism of chromatin-dependent transcription, posttranslational modification of transcription factors, cofactors and the general transcription machinery, cancer biology, and small compound development.
Our current interest is to understand the molecular basis of the epigenetic reader protein BRD4 in transcription programming, DNA repair, and cancer pathway selectivity, and further develop small molecule inhibitors to block the oncogenic function of BRD4 using biochemical, molecular, genetic, chemical biology, and genomic approaches with in vitro‑reconstituted chromatin transcription, cell‑based, and inducible knockout and knock‑in transgenic mouse disease models. Breast cancer and HPV are two disease models presently pursued in the lab.
Applicants with a recent Ph.D. degree and a strong background in transcription, chromatin, protein biochemistry, molecular biology, virology, chemical biology, mouse models, genomics, and proteomics are encouraged to apply. Expertise in animal work is preferred but not essential.
Information on our postdoctoral training program, benefits, and a virtual tour can be found at http://www.utsouthwestern.edu/postdocs.
Interested individuals should send a CV, statement of interests, and a list of three references to:
Cheng‑Ming Chiang, PhD.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, Texas 75390-8807
cheng-ming.chiang@utsouthwestern.edu
https://labs.utsouthwestern.edu/chiang-lab
UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
This position is security‑sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full‑time schedule.
To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/
Benefits UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
PPO medical plan, available day one at no cost for full‑time employee‑only coverage
100% coverage for preventive healthcare – no copay
Paid Time Off, available day one
Retirement Programs through the Teacher Retirement System of Texas (TRS)
Paid Parental Leave Benefit
Wellness programs
Tuition Reimbursement
Public Service Loan Forgiveness (PSLF) Qualified Employer
Learn more about these and other UTSW employee benefits!
#J-18808-Ljbffr