PacBio
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Lead, Manufacturing (Reagents)
role at
PacBio Join to apply for the
Lead, Manufacturing (Reagents)
role at
PacBio Get AI-powered advice on this job and more exclusive features. Position Summary
Check you match the skill requirements for this role, as well as associated experience, then apply with your CV below.
We are seeking a hands-on and highly motivated production lead to join our Reagents Manufacturing team. The ideal candidate will provide daily guidance on the production floor, ensuring that reagent manufacturing operations are executed efficiently, safely, and in compliance with SOPs, GMP/ISO standards, and production schedules.
This role serves as a working lead, balancing direct production responsibilities with tasks such as coordinating work assignments, supporting continuous improvement efforts and training operators. In addition, this person should proactively manage and resolve real-time production challenges while ensuring adherence to quality standards, including performing in-process checks, reviewing batch documentation, and supporting deviation investigations and corrective actions.
Key Responsibilities
Coordinate and lead day-to-day reagent production activities such as scheduling, ensuring adherence to batch records, SOPs, and quality standards. Act as the first point of contact for troubleshooting production issues and escalating. Train and mentor new and existing team members on procedures, equipment, and safety protocols. Monitor team productivity, material usage, and workflow to ensure output goals are met. Partner with cross-functional teams such as Quality Assurance, NPI, and Supply Chain to support root cause investigations, process improvements, and inventory accuracy. Ensure accurate and timely documentation in production records and ERP systems (e.g., SAP). Participate in and support audits, CAPAs, and change control processes. Maintain cleanroom compliance, 5S standards, and safety procedures.
Required Qualifications
High school diploma or equivalent is required. 3+ years of experience in GMP or ISO-regulated reagent or pharmaceutical production. 1+ year in a lead or informal leadership role. Strong understanding of reagent manufacturing processes including formulation, filling, and kitting. Experience working in cleanroom environments and familiarity with aseptic techniques. Proficiency in reading and executing batch records, work instructions, and material handling logs. Strong communication, organizational, and problem-solving skills. Ability to work in a fast-paced, collaborative environment with changing priorities. Comfortable lifting up to 25 lbs. and standing for extended periods. SAP experience or strong background in a related ERP platform. Excellent interpersonal, written, and verbal communication skills.
Preferred Experience
Associate degree or relevant technical certification preferred; Bachelor's degree in life sciences, chemistry, or engineering is a plus. Familiarity with MES or electronic batch records. Experience with lean manufacturing principles or continuous improvement initiatives. Prior experience with single-molecule sequencing or biotech instrumentation products is a plus.
This role is not eligible for visa sponsorship.
This role is required to be 100% onsite.
You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.
All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.
Salary Range
$69,400.00 - $104,000.00
To all Staffing and Recruiting Agencies Our Careers Site is only for individuals seeking a job at PacBio. Staffing and recruiting agencies and individuals being represented by an agency are not authorized to use this site or to submit profiles, applications or resumes, and any such submissions will be considered unsolicited. PacBio does not accept unsolicited resumes or applications from agencies. Please do not forward resumes to our jobs alias, PacBio employees or any other company location. PacBio is not responsible for any fees related to unsolicited resumes/applications.
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.
If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact us at 650-521-8000, or careers@pacificbiosciences.com for assistance.
Visit our following pages for more information on
FAQs Benefits Culture Equal Opportunity Employment
Seniority level
Seniority levelMid-Senior level Employment type
Employment typeFull-time Job function
Job functionManagement and Manufacturing Referrals increase your chances of interviewing at PacBio by 2x Sign in to set job alerts for “Manufacturing Lead” roles. San Leandro, CA $176,000.00-$215,000.00 2 months ago Palo Alto, CA $208,000.00-$221,000.00 2 weeks ago Director of Manufacturing (Consumer Durables) San Francisco Bay Area $160,000.00-$210,000.00 2 weeks ago Mountain View, CA $227,021.00-$267,083.00 3 days ago Senior Manager, Manufacturing and Operations Sunnyvale, CA $208,000.00-$293,000.00 1 week ago Senior Manager, Manufacturing Operations Redwood City, CA $165,000.00-$180,000.00 4 days ago San Jose, CA $120,000.00-$150,000.00 1 week ago Manager, Manufacturing Operations - Sauce Vice President of Operations (Food Manufacturing)
San Francisco Bay Area $140,000.00-$180,000.00 3 weeks ago Milpitas, CA $163,040.00-$239,764.00 2 weeks ago South San Francisco, CA $210,000.00-$230,000.00 4 weeks ago San Jose, CA $135,000.00-$175,000.00 2 weeks ago San Jose, CA $146,000.00-$255,000.00 3 weeks ago San Leandro, CA $90,000.00-$100,000.00 5 days ago San Jose, CA $150,000.00-$300,000.00 2 weeks ago Manager, Reagent Manufacturing Operations San Jose, CA $130,000.00-$175,000.00 1 month ago San Jose, CA $201,960.00-$224,400.00 3 days ago South San Francisco, CA $90,000.00-$210,000.00 5 days ago Fremont, CA $85,300.00-$122,700.00 13 hours ago Production Control Supervisor, Manufacturing Engineering San Francisco Bay Area $250,000.00-$350,000.00 2 weeks ago Executive Director of MFG Sciences and TechnologySenior Manager, CMC Drug Substance Manufacture Foster City, CA $190,000.00-$199,000.00 2 weeks ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
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Lead, Manufacturing (Reagents)
role at
PacBio Join to apply for the
Lead, Manufacturing (Reagents)
role at
PacBio Get AI-powered advice on this job and more exclusive features. Position Summary
Check you match the skill requirements for this role, as well as associated experience, then apply with your CV below.
We are seeking a hands-on and highly motivated production lead to join our Reagents Manufacturing team. The ideal candidate will provide daily guidance on the production floor, ensuring that reagent manufacturing operations are executed efficiently, safely, and in compliance with SOPs, GMP/ISO standards, and production schedules.
This role serves as a working lead, balancing direct production responsibilities with tasks such as coordinating work assignments, supporting continuous improvement efforts and training operators. In addition, this person should proactively manage and resolve real-time production challenges while ensuring adherence to quality standards, including performing in-process checks, reviewing batch documentation, and supporting deviation investigations and corrective actions.
Key Responsibilities
Coordinate and lead day-to-day reagent production activities such as scheduling, ensuring adherence to batch records, SOPs, and quality standards. Act as the first point of contact for troubleshooting production issues and escalating. Train and mentor new and existing team members on procedures, equipment, and safety protocols. Monitor team productivity, material usage, and workflow to ensure output goals are met. Partner with cross-functional teams such as Quality Assurance, NPI, and Supply Chain to support root cause investigations, process improvements, and inventory accuracy. Ensure accurate and timely documentation in production records and ERP systems (e.g., SAP). Participate in and support audits, CAPAs, and change control processes. Maintain cleanroom compliance, 5S standards, and safety procedures.
Required Qualifications
High school diploma or equivalent is required. 3+ years of experience in GMP or ISO-regulated reagent or pharmaceutical production. 1+ year in a lead or informal leadership role. Strong understanding of reagent manufacturing processes including formulation, filling, and kitting. Experience working in cleanroom environments and familiarity with aseptic techniques. Proficiency in reading and executing batch records, work instructions, and material handling logs. Strong communication, organizational, and problem-solving skills. Ability to work in a fast-paced, collaborative environment with changing priorities. Comfortable lifting up to 25 lbs. and standing for extended periods. SAP experience or strong background in a related ERP platform. Excellent interpersonal, written, and verbal communication skills.
Preferred Experience
Associate degree or relevant technical certification preferred; Bachelor's degree in life sciences, chemistry, or engineering is a plus. Familiarity with MES or electronic batch records. Experience with lean manufacturing principles or continuous improvement initiatives. Prior experience with single-molecule sequencing or biotech instrumentation products is a plus.
This role is not eligible for visa sponsorship.
This role is required to be 100% onsite.
You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.
All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.
Salary Range
$69,400.00 - $104,000.00
To all Staffing and Recruiting Agencies Our Careers Site is only for individuals seeking a job at PacBio. Staffing and recruiting agencies and individuals being represented by an agency are not authorized to use this site or to submit profiles, applications or resumes, and any such submissions will be considered unsolicited. PacBio does not accept unsolicited resumes or applications from agencies. Please do not forward resumes to our jobs alias, PacBio employees or any other company location. PacBio is not responsible for any fees related to unsolicited resumes/applications.
All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.
If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact us at 650-521-8000, or careers@pacificbiosciences.com for assistance.
Visit our following pages for more information on
FAQs Benefits Culture Equal Opportunity Employment
Seniority level
Seniority levelMid-Senior level Employment type
Employment typeFull-time Job function
Job functionManagement and Manufacturing Referrals increase your chances of interviewing at PacBio by 2x Sign in to set job alerts for “Manufacturing Lead” roles. San Leandro, CA $176,000.00-$215,000.00 2 months ago Palo Alto, CA $208,000.00-$221,000.00 2 weeks ago Director of Manufacturing (Consumer Durables) San Francisco Bay Area $160,000.00-$210,000.00 2 weeks ago Mountain View, CA $227,021.00-$267,083.00 3 days ago Senior Manager, Manufacturing and Operations Sunnyvale, CA $208,000.00-$293,000.00 1 week ago Senior Manager, Manufacturing Operations Redwood City, CA $165,000.00-$180,000.00 4 days ago San Jose, CA $120,000.00-$150,000.00 1 week ago Manager, Manufacturing Operations - Sauce Vice President of Operations (Food Manufacturing)
San Francisco Bay Area $140,000.00-$180,000.00 3 weeks ago Milpitas, CA $163,040.00-$239,764.00 2 weeks ago South San Francisco, CA $210,000.00-$230,000.00 4 weeks ago San Jose, CA $135,000.00-$175,000.00 2 weeks ago San Jose, CA $146,000.00-$255,000.00 3 weeks ago San Leandro, CA $90,000.00-$100,000.00 5 days ago San Jose, CA $150,000.00-$300,000.00 2 weeks ago Manager, Reagent Manufacturing Operations San Jose, CA $130,000.00-$175,000.00 1 month ago San Jose, CA $201,960.00-$224,400.00 3 days ago South San Francisco, CA $90,000.00-$210,000.00 5 days ago Fremont, CA $85,300.00-$122,700.00 13 hours ago Production Control Supervisor, Manufacturing Engineering San Francisco Bay Area $250,000.00-$350,000.00 2 weeks ago Executive Director of MFG Sciences and TechnologySenior Manager, CMC Drug Substance Manufacture Foster City, CA $190,000.00-$199,000.00 2 weeks ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr