Clearance Jobs
Senior Bacterial Core Technician
The Alaka`ina Foundation Family of Companies (FOCs) has a potential need for a Senior Bacterial Core Technician to support our government customer located in Fort Detrick, Frederick, MD. Description of Responsibilities: Responsible for BSL-3 laboratory operations and training in animal manipulations. Perform in vitro Minimum Inhibition Concentration (MIC) testing of potential therapeutic compounds against Tier 1 bacteria. Participate in mouse, rat, rabbit, or other small animal studies. Participate in weekly lab meetings and assist in development and design with current and future in vitro and in vivo work. Participate in mouse, rat, rabbit, or other small animal BSL-2 pharmacokinetics and toxicology studies. Support the in vivo pharmacology research program and contribute to the multidisciplinary research team. Assist with data analyses and drafting reports for internal or external customers. Work with mass spectrometry, chromatography, HPLC MS/MS, specifically Sciex platforms coupled with Shimadzu HPLCs other and biophysical techniques. Perform bioanalytical data acquisition, data analysis, and reporting of results using Applied Biosystems Analyst, Excel, and the Mass Spec Quantitation Software MultiQuant. Complete approximately 25 media/reagent preparations per year. Assist with approximately 5 animal challenges per year and 10 bacterial challenge preparations. Perform approximately 400 animal injections per year; 400 animal observations per year. Support divisional in vivo projects by completing approximately 500 bacterial burdens in animal tissue per year. Perform approximately 500 small animal necropsies per year. Process approximately 300 animal gavage and approximately 125 animal blood collections per year. Place approximately 50 GFEBS orders per year for supplies and equipment. Maintain laboratories in BSL-2 and BSL-3. Perform or assist with BSAT Inventory Management weekly. Conduct or assist with Equipment Inventory Management twice a year in BSL-2 and BSL-3. Perform or assist with monthly Laboratory Management to include safety functions and chemical inventory. Review relevant literature monthly. Maintain a GLP training folder and be compliant with all GLP regulations when applicable. Directly contribute to the design, rationale, and be point-of-contact for 10 small animal studies. Contribute to study progress reports and scientific manuscripts. Assist in establishing up to 28 new active material transfer agreements and cooperative research and development agreements. Other duties as assigned by Supervisor. Required Degree/Education/Certification: Bachelor's degree in Biology, Microbiology or similar science and 5 years of relevant laboratory experience. Required Skills and Experience: Two to three years performing BSL-3 laboratory operations and training in animal manipulations. Two to three years performing in-vitro Minimum Inhibition Concentration (MIC) testing. Willingness to work with diversity sets of Bacillus anthracis, Yersinia pestis, Francisella tularensis, Burkholderia mallei, and Burkholderia pseudomallei. Three to five years conducting small animal studies. Two to three years' experience working within IACUC approved protocols. Research experience in pharmacology, pharmacokinetics, and pharmacodynamics. Direct experience in in-process testing and characterization of biopharmaceutical products. Two to three years' experience with Applied Biosystems Analyst, Excel, and the Mass Spec Quantitation Software MultiQuant. Two to three years performing Animal Necropsies, animal gavage, and animal blood collections. Two to three years performing Equipment Inventory Management. Two to three years performing Laboratory Management within BSL-2 and BSL-3 environments. Required Citizenship and Clearance: U.S. Citizen BPRP and CS-PRP enrollment required. Must pass NACI background check. The Alaka`ina Foundation Family of Companies (FOCs) is a fast-growing government service provider. Employees enjoy competitive salaries. Eligible full-time employees enjoy a 401K plan with company match; medical, dental, disability, and life insurance coverage; tuition reimbursement; paid time off; and 11 paid holidays. We are an Equal Opportunity/Affirmative Action Employer of individuals with disabilities and veterans. We do not illegally discriminate in employment decisions on the basis of any protected categories.
The Alaka`ina Foundation Family of Companies (FOCs) has a potential need for a Senior Bacterial Core Technician to support our government customer located in Fort Detrick, Frederick, MD. Description of Responsibilities: Responsible for BSL-3 laboratory operations and training in animal manipulations. Perform in vitro Minimum Inhibition Concentration (MIC) testing of potential therapeutic compounds against Tier 1 bacteria. Participate in mouse, rat, rabbit, or other small animal studies. Participate in weekly lab meetings and assist in development and design with current and future in vitro and in vivo work. Participate in mouse, rat, rabbit, or other small animal BSL-2 pharmacokinetics and toxicology studies. Support the in vivo pharmacology research program and contribute to the multidisciplinary research team. Assist with data analyses and drafting reports for internal or external customers. Work with mass spectrometry, chromatography, HPLC MS/MS, specifically Sciex platforms coupled with Shimadzu HPLCs other and biophysical techniques. Perform bioanalytical data acquisition, data analysis, and reporting of results using Applied Biosystems Analyst, Excel, and the Mass Spec Quantitation Software MultiQuant. Complete approximately 25 media/reagent preparations per year. Assist with approximately 5 animal challenges per year and 10 bacterial challenge preparations. Perform approximately 400 animal injections per year; 400 animal observations per year. Support divisional in vivo projects by completing approximately 500 bacterial burdens in animal tissue per year. Perform approximately 500 small animal necropsies per year. Process approximately 300 animal gavage and approximately 125 animal blood collections per year. Place approximately 50 GFEBS orders per year for supplies and equipment. Maintain laboratories in BSL-2 and BSL-3. Perform or assist with BSAT Inventory Management weekly. Conduct or assist with Equipment Inventory Management twice a year in BSL-2 and BSL-3. Perform or assist with monthly Laboratory Management to include safety functions and chemical inventory. Review relevant literature monthly. Maintain a GLP training folder and be compliant with all GLP regulations when applicable. Directly contribute to the design, rationale, and be point-of-contact for 10 small animal studies. Contribute to study progress reports and scientific manuscripts. Assist in establishing up to 28 new active material transfer agreements and cooperative research and development agreements. Other duties as assigned by Supervisor. Required Degree/Education/Certification: Bachelor's degree in Biology, Microbiology or similar science and 5 years of relevant laboratory experience. Required Skills and Experience: Two to three years performing BSL-3 laboratory operations and training in animal manipulations. Two to three years performing in-vitro Minimum Inhibition Concentration (MIC) testing. Willingness to work with diversity sets of Bacillus anthracis, Yersinia pestis, Francisella tularensis, Burkholderia mallei, and Burkholderia pseudomallei. Three to five years conducting small animal studies. Two to three years' experience working within IACUC approved protocols. Research experience in pharmacology, pharmacokinetics, and pharmacodynamics. Direct experience in in-process testing and characterization of biopharmaceutical products. Two to three years' experience with Applied Biosystems Analyst, Excel, and the Mass Spec Quantitation Software MultiQuant. Two to three years performing Animal Necropsies, animal gavage, and animal blood collections. Two to three years performing Equipment Inventory Management. Two to three years performing Laboratory Management within BSL-2 and BSL-3 environments. Required Citizenship and Clearance: U.S. Citizen BPRP and CS-PRP enrollment required. Must pass NACI background check. The Alaka`ina Foundation Family of Companies (FOCs) is a fast-growing government service provider. Employees enjoy competitive salaries. Eligible full-time employees enjoy a 401K plan with company match; medical, dental, disability, and life insurance coverage; tuition reimbursement; paid time off; and 11 paid holidays. We are an Equal Opportunity/Affirmative Action Employer of individuals with disabilities and veterans. We do not illegally discriminate in employment decisions on the basis of any protected categories.