Chan Zuckerberg Biohub Network
Scientist, NGS & Cell Engineering (BHN - Chicago)
Chan Zuckerberg Biohub Network, Chicago, Illinois, United States, 60290
Overview
The
Chan Zuckerberg Biohub Network
(https://www.czbiohub.org/) is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The CZ Biohub Network focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments We enable individual investigators to pursue their riskiest and most innovative ideas The technologies developed at the CZ Biohub Network facilitate research by scientists and clinicians at our home institutions and beyond Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution. The Opportunity The Biohub Network is seeking a highly-skilled
Scientist
to develop, troubleshoot, and improve complex and novel next-generation sequencing (NGS) assays. The ideal candidate will have extensive experience in molecular biology, cell engineering, lentiviral systems, and cloning, and will collaborate closely with computational scientists and AI experts to generate high-quality data for training unique computational models. This is a hands-on role in a dynamic and interdisciplinary environment, with opportunities to work at the forefront of technology development and application in genomics, immunology, and AI-driven discovery. This role is based out of the Chicago location. What You'll Do
Develop and troubleshoot
novel NGS-based assays and improve existing workflows to maximize data quality and reproducibility. Design and execute
cell engineering experiments, including cloning, lentiviral transduction, CRISPR modification, and other synthetic biology techniques. Collaborate with computational scientists and AI researchers
to generate, analyze, and interpret sequencing data that will drive innovative model training. Standardize and document
protocols, ensuring reproducibility and scalability across projects. Perform and interpret data analysis , presenting findings in lab meetings, internal seminars, and external conferences. You have
PhD (or MS + 6-8 years of research experience) in Molecular Biology, Biotechnology, Genomics, or a related field. Extensive experience
(5+ years) with NGS technologies, including short- and long-read sequencing. Expertise in molecular and cell biology techniques , including cloning, CRISPR-based genome editing, lentiviral transduction, and synthetic biology. Strong troubleshooting skills
in developing and optimizing complex sequencing assays. Ability to communicate effectively across interdisciplinary teams, including biologists, data scientists, and engineers. Nice to have Proficiency in data analysis and workflow scripting tools
using Python (preferred) or R. Experience
expressing and characterizing T Cell Receptors
via in vitro assays (co-culture, tetramer staining, etc) Experience with
multi-omics approaches , including single-cell and spatial transcriptomics. Background in high throughput screening, molecular assay development,
or
immunology . Compensation
The Chicago, IL base pay range for this role is Scientist I = $92,000.00 - $127,000.00 and Scientist II = $104,000.00 - $143,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. What We Provide
Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease An environment where nothing is considered impossible, where bold and creative thinking are the norm, and where a collaborative culture allows teams of people from multiple disciplines to accomplish more than any single person can achieve alone Competitive compensation and benefits commensurate with experience If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role. We offer a robust benefits program that enables the important work Biohubbers do everyday. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists. The CZ Biohub Network
is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law. Pursuant to the California Fair Chance Act, we will consider for employment qualified applicants with arrest and conviction records. Headhunters and recruitment agencies may not submit resumes/CVs through this website or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.
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The
Chan Zuckerberg Biohub Network
(https://www.czbiohub.org/) is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The CZ Biohub Network focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments We enable individual investigators to pursue their riskiest and most innovative ideas The technologies developed at the CZ Biohub Network facilitate research by scientists and clinicians at our home institutions and beyond Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution. The Opportunity The Biohub Network is seeking a highly-skilled
Scientist
to develop, troubleshoot, and improve complex and novel next-generation sequencing (NGS) assays. The ideal candidate will have extensive experience in molecular biology, cell engineering, lentiviral systems, and cloning, and will collaborate closely with computational scientists and AI experts to generate high-quality data for training unique computational models. This is a hands-on role in a dynamic and interdisciplinary environment, with opportunities to work at the forefront of technology development and application in genomics, immunology, and AI-driven discovery. This role is based out of the Chicago location. What You'll Do
Develop and troubleshoot
novel NGS-based assays and improve existing workflows to maximize data quality and reproducibility. Design and execute
cell engineering experiments, including cloning, lentiviral transduction, CRISPR modification, and other synthetic biology techniques. Collaborate with computational scientists and AI researchers
to generate, analyze, and interpret sequencing data that will drive innovative model training. Standardize and document
protocols, ensuring reproducibility and scalability across projects. Perform and interpret data analysis , presenting findings in lab meetings, internal seminars, and external conferences. You have
PhD (or MS + 6-8 years of research experience) in Molecular Biology, Biotechnology, Genomics, or a related field. Extensive experience
(5+ years) with NGS technologies, including short- and long-read sequencing. Expertise in molecular and cell biology techniques , including cloning, CRISPR-based genome editing, lentiviral transduction, and synthetic biology. Strong troubleshooting skills
in developing and optimizing complex sequencing assays. Ability to communicate effectively across interdisciplinary teams, including biologists, data scientists, and engineers. Nice to have Proficiency in data analysis and workflow scripting tools
using Python (preferred) or R. Experience
expressing and characterizing T Cell Receptors
via in vitro assays (co-culture, tetramer staining, etc) Experience with
multi-omics approaches , including single-cell and spatial transcriptomics. Background in high throughput screening, molecular assay development,
or
immunology . Compensation
The Chicago, IL base pay range for this role is Scientist I = $92,000.00 - $127,000.00 and Scientist II = $104,000.00 - $143,000.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. What We Provide
Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease An environment where nothing is considered impossible, where bold and creative thinking are the norm, and where a collaborative culture allows teams of people from multiple disciplines to accomplish more than any single person can achieve alone Competitive compensation and benefits commensurate with experience If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role. We offer a robust benefits program that enables the important work Biohubbers do everyday. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists. The CZ Biohub Network
is an equal opportunity employer committed to diversity of thought, ideas and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law. Pursuant to the California Fair Chance Act, we will consider for employment qualified applicants with arrest and conviction records. Headhunters and recruitment agencies may not submit resumes/CVs through this website or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.
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