Valora Therapeutics, Inc.
Senior Scientist, Immunology & Immuno-oncology
Valora Therapeutics, Inc., San Diego, California, United States, 92101
ABOUT VALORA THERAPEUTICS INC.
Valora Therapeutics Inc., based in San Diego, CA, is a pre-clinical stage biopharmaceutical company revolutionizing antibody therapeutics. Founded on the pioneering platform invented by Nobel Laureate Dr. Carolyn Bertozzi (Stanford), our proprietary chimeric antibody technology unlocks novel immune signaling mechanisms, driving transformative therapies in oncology, autoimmune diseases, and beyond.
ABOUT THE OPPORTUNITY
We are seeking a highly motivated
Senior Scientist
to join our R&D Operations team and advance our next-generation antibody therapeutics. This lab-based role offers the chance to work at the cutting edge of antibody engineering, immunology and immune-oncology contributing to groundbreaking drug discovery. KEY RESPONSIBILITIES Design and Execute Immunological Assays Develop and optimize advanced in vitro and ex vivo assays to evaluate antibody mechanisms, immune modulation, and effector cell engagement.
Data Analysis and Interpretation Analyze complex datasets using tools like GraphPad Prism, FlowJo, etc., and present findings to cross-functional teams.
Innovate and Hypothesize Propose novel immunological targets and mechanisms to expand Valora's R&D therapeutic development.
Support Regulatory Milestones Contribute to IND-enabling studies and filings.
Collaborate Work closely with interdisciplinary teams to drive project success.
ABOUT YOU Education and Experience PhD in Immunology, Molecular Biology, or related field with 3+ years of relevant post-doctoral experience, or MS with 6+ years of experience in a biopharmaceutical setting. · A proven track record of scientific productivity, including publications, patents, and presentations at scientific conferences in the areas of immunology and/or immuno-oncology. Technical Skills Immunology:
Advanced understanding of cellular and molecular immunology and Immuno-oncology, with expertise in methods to enhance innate and adaptive immunity in Immuno-oncology and reduce immune activity for autoimmunity. Advanced Flow Cytometry Expertise in immune cell phenotyping and functional analysis.
Primary Immune Cell Systems Deep experience with human and mouse immune cell culture, co-culture in translational cellular systems.
Immunological Assays Expert-level proficiency in immunological assay design and execution with isolated primary human and mouse immune cells or PBMCs, including proficiency in cytotoxicity assays, cytokine detection (e.g., MSD, multiplex bead assays), and functional assays (ADCC, ADCP, CDC). Antibody Engineering Familiarity with Fc engineering, bispecific/multispecific antibodies, or related technologies.
Data Analysis Strong skills in statistical interpretation of scientific data.
Experimental Design Ability to design well-controlled experiments, including power analysis for sample size determination.
Literature Review Experience with systematic reviews and critical evaluation of scientific literature.
Documentation Excellent record-keeping using electronic lab notebooks (ELNs) and adherence to data integrity standards.
Personal Qualities Critical Thinker Hypothesis-driven with creative problem-solving skills.
Self-Driven Highly self-motivated, taking personal accountability for outcomes and demonstrating pride in delivering excellence in execution. Communicator Strong written and verbal skills to present complex data clearly.
Collaborative Thrives in cross-functional, fast-paced team environments.
Adaptable Quick to learn new techniques and concepts.
Committed Committed to scientific excellence and data integrity and committed for the success of the team and the company.
Passionate Driven by scientific innovation and a desire to impact patients' lives.
WHY JOIN VALORA? Pioneering Science Be at the forefront of antibody therapeutic development with a platform invented by a Nobel Laureate.
Impactful Work Contribute to transformative therapies for oncology and immune diseases.
Collaborative Culture Join a dynamic, entrepreneurial team that values innovation and scientific excellence.
Career Growth Professional development in a rapidly growing biotech.
COMPENSATION AND BENEFITS Competitive Package Includes salary, stock options, and performance-based bonuses.
Comprehensive Benefits Medical, dental, vision, 401(k), life insurance, flexible vacation, parental leave, flexible spending accounts, year-end shut down, and voluntary insurance coverage.
Work Environment Full-time, on-site role in our state-of-the-art San Diego laboratories (not remote).
Annual Salary Range: $135,000-175,000 JOIN US At Valora Therapeutics, you'll harness the power of protein engineering to redefine medicine. Apply now to shape the future of biotherapeutics! Valora Therapeutics Inc. is an equal opportunity employer committed to diversity and inclusion.
Senior Scientist
to join our R&D Operations team and advance our next-generation antibody therapeutics. This lab-based role offers the chance to work at the cutting edge of antibody engineering, immunology and immune-oncology contributing to groundbreaking drug discovery. KEY RESPONSIBILITIES Design and Execute Immunological Assays Develop and optimize advanced in vitro and ex vivo assays to evaluate antibody mechanisms, immune modulation, and effector cell engagement.
Data Analysis and Interpretation Analyze complex datasets using tools like GraphPad Prism, FlowJo, etc., and present findings to cross-functional teams.
Innovate and Hypothesize Propose novel immunological targets and mechanisms to expand Valora's R&D therapeutic development.
Support Regulatory Milestones Contribute to IND-enabling studies and filings.
Collaborate Work closely with interdisciplinary teams to drive project success.
ABOUT YOU Education and Experience PhD in Immunology, Molecular Biology, or related field with 3+ years of relevant post-doctoral experience, or MS with 6+ years of experience in a biopharmaceutical setting. · A proven track record of scientific productivity, including publications, patents, and presentations at scientific conferences in the areas of immunology and/or immuno-oncology. Technical Skills Immunology:
Advanced understanding of cellular and molecular immunology and Immuno-oncology, with expertise in methods to enhance innate and adaptive immunity in Immuno-oncology and reduce immune activity for autoimmunity. Advanced Flow Cytometry Expertise in immune cell phenotyping and functional analysis.
Primary Immune Cell Systems Deep experience with human and mouse immune cell culture, co-culture in translational cellular systems.
Immunological Assays Expert-level proficiency in immunological assay design and execution with isolated primary human and mouse immune cells or PBMCs, including proficiency in cytotoxicity assays, cytokine detection (e.g., MSD, multiplex bead assays), and functional assays (ADCC, ADCP, CDC). Antibody Engineering Familiarity with Fc engineering, bispecific/multispecific antibodies, or related technologies.
Data Analysis Strong skills in statistical interpretation of scientific data.
Experimental Design Ability to design well-controlled experiments, including power analysis for sample size determination.
Literature Review Experience with systematic reviews and critical evaluation of scientific literature.
Documentation Excellent record-keeping using electronic lab notebooks (ELNs) and adherence to data integrity standards.
Personal Qualities Critical Thinker Hypothesis-driven with creative problem-solving skills.
Self-Driven Highly self-motivated, taking personal accountability for outcomes and demonstrating pride in delivering excellence in execution. Communicator Strong written and verbal skills to present complex data clearly.
Collaborative Thrives in cross-functional, fast-paced team environments.
Adaptable Quick to learn new techniques and concepts.
Committed Committed to scientific excellence and data integrity and committed for the success of the team and the company.
Passionate Driven by scientific innovation and a desire to impact patients' lives.
WHY JOIN VALORA? Pioneering Science Be at the forefront of antibody therapeutic development with a platform invented by a Nobel Laureate.
Impactful Work Contribute to transformative therapies for oncology and immune diseases.
Collaborative Culture Join a dynamic, entrepreneurial team that values innovation and scientific excellence.
Career Growth Professional development in a rapidly growing biotech.
COMPENSATION AND BENEFITS Competitive Package Includes salary, stock options, and performance-based bonuses.
Comprehensive Benefits Medical, dental, vision, 401(k), life insurance, flexible vacation, parental leave, flexible spending accounts, year-end shut down, and voluntary insurance coverage.
Work Environment Full-time, on-site role in our state-of-the-art San Diego laboratories (not remote).
Annual Salary Range: $135,000-175,000 JOIN US At Valora Therapeutics, you'll harness the power of protein engineering to redefine medicine. Apply now to shape the future of biotherapeutics! Valora Therapeutics Inc. is an equal opportunity employer committed to diversity and inclusion.