Gilead Sciences
Overview
Gilead Sciences, Inc. is a research-based biopharmaceutical company focusing on therapies for life-threatening diseases. The successful candidate will contribute to biologics analytical operations, including biochemical characterization and method development to support clinical and commercial programs. This role involves collaboration across teams to advance analytical capabilities and support drug candidate development and marketed drug research. Key Responsibilities
Support late-stage assay development by performing mass spectrometry to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context. Contribute to analytical method development and qualification for protein characterization activities. Support comparability and stability studies using mass spectrometry. Operate, maintain, and troubleshoot Waters, Sciex, Agilent, Bruker QTOFs, and Thermo Orbitrap mass spectrometers. Collaborate with team members to develop advanced techniques for substance, assay, and tool characterization. Represent the Structure Characterization group in cross-functional project teams. Participate in technology transfer of assays from analytical development to QC and external CRO/CMOs. Coordinate analysis of in-process and product-related impurities for process comparability studies. Conduct scientific research to support drug candidate development and marketed drug research. Advise project teams on experiment planning and execution, considering economic, regulatory, and safety factors. Present experimental results, interpret data, and draw conclusions. Stay current with scientific literature and apply relevant knowledge to projects. Represent the company at national and international conferences. Basic Qualifications
BS degree with at least six (6) years of industry experience OR MS degree with at least four (4) years of industry experience. Strong knowledge of mass spectrometry, experimental design, and assay development. Excellent verbal, technical writing, and interpersonal communication skills. Ability to work independently and collaboratively in a matrixed environment. Strong organizational and planning skills. Proficient in Microsoft Office applications. Preferred Qualifications
PhD in Chemistry or a related discipline with limited industry experience Familiarity with techniques such as:
Peptide mapping by LC-MS/MS Intact mass analysis MS/MS for protein and carbohydrate structural elucidation/quantification Kinetic analyses Ultra-performance chromatography Proteolytic/chemical processing
Knowledge of ICH guidelines and GMP. Expertise in mass spectrometry analysis software (Protein Metrics, Thermo BioPharma Finder, Skyline). Experience with data analysis and visualization tools (Python, R, JMP, Spotfire). Demonstrated ability to mentor junior team members and lead in cross-functional environments. Compensation and Benefits
The base pay range for this position is $146,540.00/yr - $189,640.00/yr. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing Equal Employment Opportunity and Notices
Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants and fostering an inclusive work environment. Employment decisions are made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, disability, genetic information or protected characteristics, or other prohibited grounds under applicable laws. Applicants requiring accommodation may contact ApplicantAccommodations@gilead.com. See the Know Your Rights poster for more information. Gilead adheres to applicable laws including the Family and Medical Leave Act, and the Employee Polygraph Protection Act. Job Details
Seniority level: Not Applicable Employment type: Full-time Job function: Research, Analyst, and Information Technology Industries: Biotechnology Research and Pharmaceutical Manufacturing Note: This description reflects the responsibilities and qualifications of the role and does not request or require any confidential information.
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Gilead Sciences, Inc. is a research-based biopharmaceutical company focusing on therapies for life-threatening diseases. The successful candidate will contribute to biologics analytical operations, including biochemical characterization and method development to support clinical and commercial programs. This role involves collaboration across teams to advance analytical capabilities and support drug candidate development and marketed drug research. Key Responsibilities
Support late-stage assay development by performing mass spectrometry to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context. Contribute to analytical method development and qualification for protein characterization activities. Support comparability and stability studies using mass spectrometry. Operate, maintain, and troubleshoot Waters, Sciex, Agilent, Bruker QTOFs, and Thermo Orbitrap mass spectrometers. Collaborate with team members to develop advanced techniques for substance, assay, and tool characterization. Represent the Structure Characterization group in cross-functional project teams. Participate in technology transfer of assays from analytical development to QC and external CRO/CMOs. Coordinate analysis of in-process and product-related impurities for process comparability studies. Conduct scientific research to support drug candidate development and marketed drug research. Advise project teams on experiment planning and execution, considering economic, regulatory, and safety factors. Present experimental results, interpret data, and draw conclusions. Stay current with scientific literature and apply relevant knowledge to projects. Represent the company at national and international conferences. Basic Qualifications
BS degree with at least six (6) years of industry experience OR MS degree with at least four (4) years of industry experience. Strong knowledge of mass spectrometry, experimental design, and assay development. Excellent verbal, technical writing, and interpersonal communication skills. Ability to work independently and collaboratively in a matrixed environment. Strong organizational and planning skills. Proficient in Microsoft Office applications. Preferred Qualifications
PhD in Chemistry or a related discipline with limited industry experience Familiarity with techniques such as:
Peptide mapping by LC-MS/MS Intact mass analysis MS/MS for protein and carbohydrate structural elucidation/quantification Kinetic analyses Ultra-performance chromatography Proteolytic/chemical processing
Knowledge of ICH guidelines and GMP. Expertise in mass spectrometry analysis software (Protein Metrics, Thermo BioPharma Finder, Skyline). Experience with data analysis and visualization tools (Python, R, JMP, Spotfire). Demonstrated ability to mentor junior team members and lead in cross-functional environments. Compensation and Benefits
The base pay range for this position is $146,540.00/yr - $189,640.00/yr. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing Equal Employment Opportunity and Notices
Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants and fostering an inclusive work environment. Employment decisions are made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, disability, genetic information or protected characteristics, or other prohibited grounds under applicable laws. Applicants requiring accommodation may contact ApplicantAccommodations@gilead.com. See the Know Your Rights poster for more information. Gilead adheres to applicable laws including the Family and Medical Leave Act, and the Employee Polygraph Protection Act. Job Details
Seniority level: Not Applicable Employment type: Full-time Job function: Research, Analyst, and Information Technology Industries: Biotechnology Research and Pharmaceutical Manufacturing Note: This description reflects the responsibilities and qualifications of the role and does not request or require any confidential information.
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