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Getting Hired

Sr Scientist, Analytical Ops

Getting Hired, Oceanside, California, United States, 92058

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Overview

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We are committed to inclusive leadership and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences, Inc. is a research-based biopharmaceutical company founded in 1987. We deliver life-saving therapies to patients in need. By joining Gilead, you will further our mission to address unmet medical needs and improve life by advancing the care of patients with life-threatening diseases. The successful candidate will possess a detailed understanding of proteins and carbohydrates. The candidate must be highly motivated to contribute to the research and development of biologics targeting unmet medical needs through biochemical characterization and novel method development supporting clinical and commercial programs. Experience in several of the following fields is strongly desired: analytical chemistry, biochemistry, biological mass spectrometry, high performance or ultra-performance liquid chromatography, electrophoretic separations, enzymology, statistics, chemical and biophysical structural elucidation, and bioinformatics. Relocation At a future date this position will relocate to the corporate HQ in Foster City, CA. Key Responsibilities

Support late-stage assay development by performing mass spectrometry to characterize molecules, degradation pathways, and define critical quality attributes in a phase-appropriate context. Contribute to analytical method development and qualification for protein characterization. Develop innovative assays to gain competitive advantages over standard industry practices. Support comparability and stability studies using mass spectrometry. Operate, maintain, and troubleshoot Waters, Sciex, Bruker QTOFs, and Thermo Orbitrap mass spectrometers. Solve complex problems requiring evaluation of intangible variables using logic, ingenuity, and creativity. Collaborate with junior and senior team members to advance state-of-the-art characterization techniques. Represent the Structure Characterization group in cross-functional project teams. Participate in technology transfer of assays to QC and external CRO/CMOs. Coordinate analysis of in-process and product-related impurities for process comparability studies. Conduct scientific research to support drug candidate development and marketed drug research. Advise project teams on experiment planning and execution, considering economic, regulatory, and safety factors. Present results, interpret data, and draw conclusions from experimental findings. Stay current with scientific literature and apply relevant knowledge to projects. Represent the company at national and international conferences. Basic Qualifications

BS degree with at least 8 years of industry experience OR MS degree with at least 6 years of industry experience. Strong knowledge of mass spectrometry, experimental design, and assay development. Demonstrated ability to lead in a cross-functional environment and mentor junior team members. Ability to work independently with minimal supervision. Excellent verbal, technical writing, and interpersonal communication skills. Proficient in Microsoft Office applications. Preferred Qualifications

PhD in Chemistry or related discipline with at least 2 years of industry experience Familiarity with techniques such as peptide mapping by LC-MS/MS, intact mass analysis, MS/MS for protein and carbohydrate structural elucidation/quantification, kinetic analyses, ultra-performance chromatography, and proteolytic/chemical processing Knowledge of ICH guidelines and GMP. Expertise in mass spectrometry analysis software (Protein Metrics, Thermo BioPharma Finder, Skyline). Experience with data analysis and visualization tools (Python, R, JMP, Spotfire). Strong organizational and planning skills. Ability to work effectively in a matrixed environment and communicate assay results and issues clearly. Salary range for this position is $153,935.00 - $199,210.00. Compensation is based on factors including experience, qualifications, and geographic location. This position may be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary by role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans. For additional benefits information, visit the Gilead Careers benefits page. Eligible employees may participate in benefit plans, subject to plan terms. Gilead is an equal employment opportunity employer. We are committed to fostering an inclusive work environment with diverse perspectives, backgrounds, and experiences. Applicants will be considered for employment without regard to race, color, religion, national origin, sex, age, sexual orientation, disability, genetic information, gender identity or expression, veteran status, or other protected characteristics. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

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