Generalproximity
Research Associate, Drug Discovery
Generalproximity, San Francisco, California, United States, 94199
Our Story
A seed-stage startup building the next generation of induced proximity medicines (IPMs). Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges that have remained unapproachable to other modalities. We are seeking a first-rate research associate to help us pioneer this uncharted frontier of drug discovery. The Position
We are seeking an experienced Research Associate to be a key member of our Platform/Drug Discovery Team. In this position, you will work in close conjunction with our Biology Team in the development of our core drug discovery technology and the generation of a completely novel class of therapeutics. Your responsibilities will include: designing and executing experiments independently or in collaboration with senior researchers; contributing to the development and optimization of experimental protocols and assays; preparation and handling of biological samples including mammalian cell cultures; performing advanced laboratory techniques and methodologies; data analysis and interpretation under the guidance of senior researchers; and recording and organizing experimental data accurately and efficiently. About You
High Agency.
Initiative, independence, and self-accountability are valued traits. Enthusiastic.
We value people who are excited about their work and helping build a high-energy team. Intensity and Grit.
Early-stage startups are hard; drug discovery is doubly so. We seek candidates who can persist through complex problems with a supportive team. Prosocial.
We aim to create life-saving medicines for patients who need them, and you should as well. Qualifications & Nice-To-Haves
BS or MS in Biology, Biochemistry, Molecular Biology, or a related field. Industry experience is desirable, but the ability to work hard and learn fast is more important. Deep understanding of small-molecule drug discovery and its relationship to human disease. Top-notch written and oral communication skills. Proficiency in:
Mammalian cell culture, passaging/seeding cells, aseptic technique Molecular biology/cloning, PCR, and other common biology techniques like western blotting, flow cytometry, microscopy, and biochemical assays Assay development and optimization Strong understanding of basic biological principles and laboratory techniques Strong problem-solving skills and the ability to work independently as well as part of a team Nice To Have:
2+ years of post-degree experience Experience with HTS and phenotypic cell-based assay development Transient/stable protein expression and purification, immunoprecipitation assays Experience working with CRISPR-Cas systems Familiarity with data analysis software (e.g., Prism) and statistical tools Familiarity with automated robotic dispensers, liquid handlers Prior experience on teams that have advanced research to the clinic Strong equity incentives. We seek candidates who will bring a strong sense of ownership to drive their project areas forward. Top-tier medical, dental, and vision coverage plus One Medical membership. Education and health/fitness incentive programs. Reading budget; we will buy you books. About Us
Work Hard/Play Hard.
We value time as a resource and strive for a culture with efficient meetings and predictable time off. Strong Communication.
We prefer well-written documents and clear objectives. Writing First.
We emphasize writing to improve clarity, reproducibility, and alignment. Growth.
As an early-stage startup, we value independent, can-do scientists who can wear multiple hats. Title and compensation are commensurate with experience. We welcome applications from diverse backgrounds. We look forward to hearing from you.
#J-18808-Ljbffr
A seed-stage startup building the next generation of induced proximity medicines (IPMs). Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges that have remained unapproachable to other modalities. We are seeking a first-rate research associate to help us pioneer this uncharted frontier of drug discovery. The Position
We are seeking an experienced Research Associate to be a key member of our Platform/Drug Discovery Team. In this position, you will work in close conjunction with our Biology Team in the development of our core drug discovery technology and the generation of a completely novel class of therapeutics. Your responsibilities will include: designing and executing experiments independently or in collaboration with senior researchers; contributing to the development and optimization of experimental protocols and assays; preparation and handling of biological samples including mammalian cell cultures; performing advanced laboratory techniques and methodologies; data analysis and interpretation under the guidance of senior researchers; and recording and organizing experimental data accurately and efficiently. About You
High Agency.
Initiative, independence, and self-accountability are valued traits. Enthusiastic.
We value people who are excited about their work and helping build a high-energy team. Intensity and Grit.
Early-stage startups are hard; drug discovery is doubly so. We seek candidates who can persist through complex problems with a supportive team. Prosocial.
We aim to create life-saving medicines for patients who need them, and you should as well. Qualifications & Nice-To-Haves
BS or MS in Biology, Biochemistry, Molecular Biology, or a related field. Industry experience is desirable, but the ability to work hard and learn fast is more important. Deep understanding of small-molecule drug discovery and its relationship to human disease. Top-notch written and oral communication skills. Proficiency in:
Mammalian cell culture, passaging/seeding cells, aseptic technique Molecular biology/cloning, PCR, and other common biology techniques like western blotting, flow cytometry, microscopy, and biochemical assays Assay development and optimization Strong understanding of basic biological principles and laboratory techniques Strong problem-solving skills and the ability to work independently as well as part of a team Nice To Have:
2+ years of post-degree experience Experience with HTS and phenotypic cell-based assay development Transient/stable protein expression and purification, immunoprecipitation assays Experience working with CRISPR-Cas systems Familiarity with data analysis software (e.g., Prism) and statistical tools Familiarity with automated robotic dispensers, liquid handlers Prior experience on teams that have advanced research to the clinic Strong equity incentives. We seek candidates who will bring a strong sense of ownership to drive their project areas forward. Top-tier medical, dental, and vision coverage plus One Medical membership. Education and health/fitness incentive programs. Reading budget; we will buy you books. About Us
Work Hard/Play Hard.
We value time as a resource and strive for a culture with efficient meetings and predictable time off. Strong Communication.
We prefer well-written documents and clear objectives. Writing First.
We emphasize writing to improve clarity, reproducibility, and alignment. Growth.
As an early-stage startup, we value independent, can-do scientists who can wear multiple hats. Title and compensation are commensurate with experience. We welcome applications from diverse backgrounds. We look forward to hearing from you.
#J-18808-Ljbffr