Bristol Myers Squibb
Principal/Sr Principal Scientist, Hematology Lead Translational Development
Bristol Myers Squibb, Princeton, New Jersey, us, 08543
Overview
Principal/Sr Principal Scientist, Hematology Lead Translational Development Role overview: Development and execution of myeloma asset centric translational strategies in hematology for assigned programs. Lead biomarker strategy implementation for clinical programs, develop reports/publications on preclinical and translational data to support asset development, and contribute to regulatory submissions. Works on cross-functional teams with laboratory and disease scientists, clinical, medical, regulatory, diagnostics, and external collaborators/KOLs. Location options: Summit, NJ; Princeton/LVL, NJ; Cambridge Crossing, MA. Responsibilities
Oversees biomarker execution in clinical trials and supports biomarker sampling and subsequent data analysis. Leads the development of asset-specific translational goals and objectives for the Hematology Translational Medicine group. Represents Translational Medicine on cross-functional strategy and global project teams. Supports regulatory submissions, engages in regulatory interactions, and writes translational sections for regulatory responses and answers to regulatory queries for the TM group. Presents data at scientific advisory boards to support drug programs/projects. Prepares and delivers presentations within the department and externally as required. Responsible for selection and delivery of pharmacodynamic and biomarker assays, including assessing the need for companion/complementary diagnostics for asset programs. May perform advisory and mentoring roles for junior scientists. Qualifications
PhD in Hematology/Oncology or related field with minimum 6 years in industry and/or academia. Track record in drug discovery/development, leading translational/biomarker studies or deploying technologies/assays for enhanced translational capabilities; prior leadership in similar settings is preferred. Experience with translational/biomarker strategies for early or late-stage clinical trials or investigator-sponsored trials in academia. Clinical protocol authoring and review of regulatory documents. Working knowledge of biomarker platforms including genomics, gene expression, immune profiling, and flow cytometry. Excellent data analysis and problem-solving skills; strong verbal and written communication skills, with experience in manuscripts/publications, scientific presentations, and regulatory submissions (INDs/NDAs). Proven scientific and project leadership experience in global teams, with ability to manage people and projects. Compensation & Benefits
Pay ranges vary by location: New Jersey Principal $140,000–$165,000; Senior Principal $165,000–$185,000 (plus incentive cash and stock opportunities, based on eligibility). Cambridge, MA Principal $165,000–$185,000; Senior Principal $185,000–$215,000 (plus incentive cash and stock opportunities, based on eligibility). The starting pay considers job characteristics, location, skills and experience. Final compensation is determined based on demonstrated experience. Benefits vary by location; more details on benefits are available on the careers site. Location & On-site Expectations
On-site requirements vary by role: site-essential (100% onsite), site-by-design (hybrid with at least 50% onsite), field-based or remote-by-design (travel to customers/patients/business partners as needed). Company Values & Additional Information
BMS emphasizes transforming patients’ lives through science, with a culture of passion, innovation, urgency, accountability, inclusion, and integrity. The company provides a range of benefits and well-being programs; eligible roles may include vaccination guidance and other health-related policies. For accessibility and equal opportunity employment information, refer to the company’s official EEO statements on the careers site.
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Principal/Sr Principal Scientist, Hematology Lead Translational Development Role overview: Development and execution of myeloma asset centric translational strategies in hematology for assigned programs. Lead biomarker strategy implementation for clinical programs, develop reports/publications on preclinical and translational data to support asset development, and contribute to regulatory submissions. Works on cross-functional teams with laboratory and disease scientists, clinical, medical, regulatory, diagnostics, and external collaborators/KOLs. Location options: Summit, NJ; Princeton/LVL, NJ; Cambridge Crossing, MA. Responsibilities
Oversees biomarker execution in clinical trials and supports biomarker sampling and subsequent data analysis. Leads the development of asset-specific translational goals and objectives for the Hematology Translational Medicine group. Represents Translational Medicine on cross-functional strategy and global project teams. Supports regulatory submissions, engages in regulatory interactions, and writes translational sections for regulatory responses and answers to regulatory queries for the TM group. Presents data at scientific advisory boards to support drug programs/projects. Prepares and delivers presentations within the department and externally as required. Responsible for selection and delivery of pharmacodynamic and biomarker assays, including assessing the need for companion/complementary diagnostics for asset programs. May perform advisory and mentoring roles for junior scientists. Qualifications
PhD in Hematology/Oncology or related field with minimum 6 years in industry and/or academia. Track record in drug discovery/development, leading translational/biomarker studies or deploying technologies/assays for enhanced translational capabilities; prior leadership in similar settings is preferred. Experience with translational/biomarker strategies for early or late-stage clinical trials or investigator-sponsored trials in academia. Clinical protocol authoring and review of regulatory documents. Working knowledge of biomarker platforms including genomics, gene expression, immune profiling, and flow cytometry. Excellent data analysis and problem-solving skills; strong verbal and written communication skills, with experience in manuscripts/publications, scientific presentations, and regulatory submissions (INDs/NDAs). Proven scientific and project leadership experience in global teams, with ability to manage people and projects. Compensation & Benefits
Pay ranges vary by location: New Jersey Principal $140,000–$165,000; Senior Principal $165,000–$185,000 (plus incentive cash and stock opportunities, based on eligibility). Cambridge, MA Principal $165,000–$185,000; Senior Principal $185,000–$215,000 (plus incentive cash and stock opportunities, based on eligibility). The starting pay considers job characteristics, location, skills and experience. Final compensation is determined based on demonstrated experience. Benefits vary by location; more details on benefits are available on the careers site. Location & On-site Expectations
On-site requirements vary by role: site-essential (100% onsite), site-by-design (hybrid with at least 50% onsite), field-based or remote-by-design (travel to customers/patients/business partners as needed). Company Values & Additional Information
BMS emphasizes transforming patients’ lives through science, with a culture of passion, innovation, urgency, accountability, inclusion, and integrity. The company provides a range of benefits and well-being programs; eligible roles may include vaccination guidance and other health-related policies. For accessibility and equal opportunity employment information, refer to the company’s official EEO statements on the careers site.
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