Novartis Group Companies
Sr. Scientist II / Principal Scientist I Biomarker Development, Translational Me
Novartis Group Companies, Cambridge, Massachusetts, us, 02140
Overview
Job Description Summary On-site Laboratory based role in Biomarker Development (BMD) within Molecular & Cellular Sciences (MCS) and Translational Medicine (TM) at Novartis Biomedical Research. BMD delivers cutting-edge biomarkers across proteins, metabolites, cells, genetics, genomics, imaging and digital endpoints to enable decision-making across drug development milestones. The Scientist in Biomarker Development will identify and implement new methodologies, develop and validate innovative biomarker solutions, and deliver high-quality data to support advance clinical programs. Collaboration with biomarker activity leads and clinical teams will drive internal and external biomarker activities and interpretation of results to support mechanistic, safety and efficacy understanding. This is an on-site (100%) laboratory role.
This is a dual level posting. The final level and title of the offer role will be determined by the hiring team based on the skills, experience and capabilities required.
Key Responsibilities
Provide technical expertise with a focus on ligand binding assays such as ELISAs (MSD, Luminex, ELLA), mass spectrometry, and point-of-care testing Develop, validate and implement targeted singleplex / multiplex biomarker assays internally and/or at external vendors Present results at internal meetings and collaborate with the MCS Activity Lead Work in a matrix environment with a team of lab scientists to apply innovative biomarker solutions Independently design, execute, and interpret experiments Ensure high quality and timely delivery of internal and external results Conduct activities in compliance with Novartis policies, values and behavior and relevant guidelines Network internally to expand scientific and technical knowledge Note: this is an on-site role (100%)
Essential Requirements
BA/MS in Biology, Biochemistry or related discipline with 4-7 years of professional hands-on experience in method development/validation of immunoassays in industry or biotechnology for Senior Scientist II; 7+ years for Principal Scientist I. Bachelor’s with 6+ years may be considered. PhD with appropriate experience will also be considered Proficiency running immunoassay platforms such as MSD, Luminex, Ella, etc. Experience with Quanterix Simoa and Mass Spectrometry is a plus Implement best practices for operation and maintenance of instrumentation Experience troubleshooting immunoassays and assay transfer to CROs Experience with multiplex assays and profiling platforms is highly desired Experience with automated Western blots; Cobas is a plus Creative, self-motivated, collaborative and independent Analytical thinking, responsibility and teamwork skills Experience in a global organization and matrix-resourcing model Good computer skills (Excel, Word, PowerPoint, SoftMaxPro, SMART Book, Spotfire, GraphPad Prism, Watson LIMS) Good English communication skills (oral and written) Understanding of regulatory requirements relevant to Biomarker Development (e.g., GCLP, ICH)
Compensation and Benefits
Novartis compensation details: Senior Scientist II range: $93,800 – $174,200/year; Principal Scientist I range: $114,100 – $195,600/year. Salary ranges effective 1/1/25 through 12/31/25; final pay may vary by location, experience, and capabilities. Total compensation may include sign-on bonus, RSUs, discretionary awards, and a full range of benefits (medical, 401(k), PTO, etc.). At offer, employee will be in an at-will position and base salary/other components may be modified for performance, department needs, or market factors.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility
The Novartis Group of Companies are committed to providing reasonable accommodations to individuals with disabilities. If you need accommodations for any part of the application process or to perform essential functions, please email us.reasonableaccommodations@novartis.com or call +1-877-395-2339 and include the job requisition number.
Salary Range
$93,800.00 - $174,200.00
Skills Desired
Analytical skills, chemistry and molecular biology proficiency; collaboration, communication, data analysis, design of experiments, attention to detail; experience in drug discovery, immunology, mammalian cell culture, and related life sciences.
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Job Description Summary On-site Laboratory based role in Biomarker Development (BMD) within Molecular & Cellular Sciences (MCS) and Translational Medicine (TM) at Novartis Biomedical Research. BMD delivers cutting-edge biomarkers across proteins, metabolites, cells, genetics, genomics, imaging and digital endpoints to enable decision-making across drug development milestones. The Scientist in Biomarker Development will identify and implement new methodologies, develop and validate innovative biomarker solutions, and deliver high-quality data to support advance clinical programs. Collaboration with biomarker activity leads and clinical teams will drive internal and external biomarker activities and interpretation of results to support mechanistic, safety and efficacy understanding. This is an on-site (100%) laboratory role.
This is a dual level posting. The final level and title of the offer role will be determined by the hiring team based on the skills, experience and capabilities required.
Key Responsibilities
Provide technical expertise with a focus on ligand binding assays such as ELISAs (MSD, Luminex, ELLA), mass spectrometry, and point-of-care testing Develop, validate and implement targeted singleplex / multiplex biomarker assays internally and/or at external vendors Present results at internal meetings and collaborate with the MCS Activity Lead Work in a matrix environment with a team of lab scientists to apply innovative biomarker solutions Independently design, execute, and interpret experiments Ensure high quality and timely delivery of internal and external results Conduct activities in compliance with Novartis policies, values and behavior and relevant guidelines Network internally to expand scientific and technical knowledge Note: this is an on-site role (100%)
Essential Requirements
BA/MS in Biology, Biochemistry or related discipline with 4-7 years of professional hands-on experience in method development/validation of immunoassays in industry or biotechnology for Senior Scientist II; 7+ years for Principal Scientist I. Bachelor’s with 6+ years may be considered. PhD with appropriate experience will also be considered Proficiency running immunoassay platforms such as MSD, Luminex, Ella, etc. Experience with Quanterix Simoa and Mass Spectrometry is a plus Implement best practices for operation and maintenance of instrumentation Experience troubleshooting immunoassays and assay transfer to CROs Experience with multiplex assays and profiling platforms is highly desired Experience with automated Western blots; Cobas is a plus Creative, self-motivated, collaborative and independent Analytical thinking, responsibility and teamwork skills Experience in a global organization and matrix-resourcing model Good computer skills (Excel, Word, PowerPoint, SoftMaxPro, SMART Book, Spotfire, GraphPad Prism, Watson LIMS) Good English communication skills (oral and written) Understanding of regulatory requirements relevant to Biomarker Development (e.g., GCLP, ICH)
Compensation and Benefits
Novartis compensation details: Senior Scientist II range: $93,800 – $174,200/year; Principal Scientist I range: $114,100 – $195,600/year. Salary ranges effective 1/1/25 through 12/31/25; final pay may vary by location, experience, and capabilities. Total compensation may include sign-on bonus, RSUs, discretionary awards, and a full range of benefits (medical, 401(k), PTO, etc.). At offer, employee will be in an at-will position and base salary/other components may be modified for performance, department needs, or market factors.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility
The Novartis Group of Companies are committed to providing reasonable accommodations to individuals with disabilities. If you need accommodations for any part of the application process or to perform essential functions, please email us.reasonableaccommodations@novartis.com or call +1-877-395-2339 and include the job requisition number.
Salary Range
$93,800.00 - $174,200.00
Skills Desired
Analytical skills, chemistry and molecular biology proficiency; collaboration, communication, data analysis, design of experiments, attention to detail; experience in drug discovery, immunology, mammalian cell culture, and related life sciences.
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