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Alaka`ina Foundation Family of Companies

Bacterial Core Lead Scientist

Alaka`ina Foundation Family of Companies, Frederick, Maryland, United States, 21701

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The Alaka`ina Foundation Family of Companies (FOCs) has a Potential need for a

Bacterial Core Lead Scientist

to support our government customer located in Frederick, MD at Fort Detrick. DESCRIPTION OF RESPONSIBILITIES: Use computer to analyze data and prepare graphs, do statistics, write lab notes and reports. Complete quarterly reports and annual progress reports per investigator. Present 2 research findings/presentations at lab meetings and approximately 23 lab meetings per year, and if required, attend approximately 2 scientific meetings or symposia (CONUS or OCONUS). Attend 12 division meetings per year and give 1 presentation per investigator. Prepare one 1st author manuscript for publication per year. Prepare approximately 2 supporting author scientific papers for publication. In charge of maintenance of ~6 microscope systems in laboratories. Responsible for ordering microscopy systems and parts. Prepare BSL-2 and BSL-3 labs for safety, bio-surety and CDC inspections. Plan and perform in vitro minimum inhibition concentration (mic) testing or potential therapeutic compounds against tier 1 bacteria. Plan and participate in mouse, rat, and rabbit studies, which include preparation of antibiotics for administration, administering drugs and vaccines, and collecting animal body fluids. Participate in weekly lab meetings and assist in development and design with current and future in vitro and in vivo work. Plan and participate in small-animal BSL-2 pharmacokinetics and toxicology studies. Support the in vivo pharmacology research program and contribute to the multidisciplinary research team. Assist in animal protocols working with bacterial pathogens. Participate in testing and purifying b. Anthracis components for efficacy studies. Write, plan and execute animal protocol. Perform ELISAs. Process flow cytometry samples. Test for endotoxin and perform endotoxin remediation when necessary. Purify bacterial products from culture supernatants per year. Conduct equipment inventory management twice a year in BSL-2 and BSL-3. Perform monthly laboratory management to include safety functions and chemical inventory. Provide 1 scientific support monthly report to include materials and methods, data and data analysis. Maintain a GLP training folder and be compliant with all GLP regulations when applicable. Other duties as assigned. REQUIRED DEGREE/EDUCATION/CERTIFICATION: Masters Degree in a biological or life science and 7 years of experience (preferred). Bachelor's degree and 5 years’ experience. REQUIRED SKILLS AND EXPERIENCE: Experience in high performance liquid chromatography coupled to mass spectroscopy (HPLC-MS). Experience in animal manipulations. Experience with in vitro antibiotic susceptibility assay systems. Knowledge of animal study design and basic knowledge of animal physiology. Familiarity with high performance liquid chromatography (HPLC), mass spectroscopy (MS), and other antibiotic determination methods. Experience in operating an HPLC/Mass Spec instrument. Ability to prepare biological samples for assay of antibiotics. REQUIRED CITIZENSHIP AND CLEARANCE: U.S. Citizen. Must pass NACI background check. Must be willing to work in a BSL 3 laboratory. Must be eligible to enroll in the BPRP and CS-PRP programs. The Alaka`ina Foundation Family of Companies (FOCs) is a fast-growing government service provider. Employees enjoy competitive salaries and benefits. We are an Equal Opportunity/Affirmative Action Employer.

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