Pfizer
Overview
The Proteomics Bench Scientist will support Pfizer to develop and optimize mass spectrometry-based proteomics workflows. This role involves sample preparation from cell lines and other matrices, high-resolution MS analysis (Orbitrap, timsTOF), and data processing using bioinformatics tools. The ideal candidate has experience with TMT or DIA quantification, LC-MS workflows, and collaborative method development. An MSc with 5+ years of experience is required; PhD candidates are preferred. Responsibilities
Responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques Development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples Working collaboratively with experts in the team to advance innovative proteomics strategies Employing different bioinformatics tools for data analysis and fitting Consistent record keeping using an electronic lab notebook (ELN) Daily interaction with managers and 3-4 colleagues in the cross-functional team for method development, laboratory work prioritization, experiment planning and execution Participation in bi-weekly group meetings and other team meetings and discussions, as relevant Minimum Qualifications
M.Sc with at least 5+ years OR PhD with 0+ years in a relevant scientific field with a documented experience in proteomics and mass-spectrometry Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA) Experience with high-resolution mass-spectrometry instruments, such as Orbitraps and timsTOF Experience with sample preparation based on enrichment (incl. affinity purification), and universal protein extraction Bioinformatics skills relevant for mass-spec data search, statistical analysis and visualization Expertise in LC-MS based proteomics. Preferable Qualifications
Experience with membrane protein analysis and/or cell surface proteomics Knowledge of cell culture techniques and experience conducting cell-based assays Experience with cell culture and cell manipulation is a plus Location/Schedule
Fully onsite role in Andover, MA Monday - Friday: 40 hours per week Please note contractors are engaged to provide services to Pfizer on a temporary basis in connection with a specific assignment. Contractors are hired and employed through Atrium, our third-party payrolling partner. This job posting is for a temporary role as an employee of Atrium on assignment at Pfizer. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements. Pay and Benefits
Pay Rate Range Min Pay Rate $47 Max Pay Rate $57 Currency USD Unit hourly Benefits Information Comprehensive Benefits Package available based on eligibility Short-Term Disability (STD) Long-Term Disability (LTD) Supplemental and Voluntary Life Insurance
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The Proteomics Bench Scientist will support Pfizer to develop and optimize mass spectrometry-based proteomics workflows. This role involves sample preparation from cell lines and other matrices, high-resolution MS analysis (Orbitrap, timsTOF), and data processing using bioinformatics tools. The ideal candidate has experience with TMT or DIA quantification, LC-MS workflows, and collaborative method development. An MSc with 5+ years of experience is required; PhD candidates are preferred. Responsibilities
Responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques Development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples Working collaboratively with experts in the team to advance innovative proteomics strategies Employing different bioinformatics tools for data analysis and fitting Consistent record keeping using an electronic lab notebook (ELN) Daily interaction with managers and 3-4 colleagues in the cross-functional team for method development, laboratory work prioritization, experiment planning and execution Participation in bi-weekly group meetings and other team meetings and discussions, as relevant Minimum Qualifications
M.Sc with at least 5+ years OR PhD with 0+ years in a relevant scientific field with a documented experience in proteomics and mass-spectrometry Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA) Experience with high-resolution mass-spectrometry instruments, such as Orbitraps and timsTOF Experience with sample preparation based on enrichment (incl. affinity purification), and universal protein extraction Bioinformatics skills relevant for mass-spec data search, statistical analysis and visualization Expertise in LC-MS based proteomics. Preferable Qualifications
Experience with membrane protein analysis and/or cell surface proteomics Knowledge of cell culture techniques and experience conducting cell-based assays Experience with cell culture and cell manipulation is a plus Location/Schedule
Fully onsite role in Andover, MA Monday - Friday: 40 hours per week Please note contractors are engaged to provide services to Pfizer on a temporary basis in connection with a specific assignment. Contractors are hired and employed through Atrium, our third-party payrolling partner. This job posting is for a temporary role as an employee of Atrium on assignment at Pfizer. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements. Pay and Benefits
Pay Rate Range Min Pay Rate $47 Max Pay Rate $57 Currency USD Unit hourly Benefits Information Comprehensive Benefits Package available based on eligibility Short-Term Disability (STD) Long-Term Disability (LTD) Supplemental and Voluntary Life Insurance
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