MUSC Health
UNIV - Post Doctoral Scholar - Department of Pharmacology and Immunology
MUSC Health, Charleston, South Carolina, United States, 29408
UNIV - Post Doctoral Scholar - Department of Pharmacology and Immunology
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Job Description Summary Seeking an individual, preferably with microsurgical experience, for a position in neuroimmunology that encompasses basic and translational research. Work will focus on the complement system and neuroinflammatory mechanisms. Projects involve investigating acute and chronic neuroimmune responses after stroke or traumatic brain injury, including long‑term neurodegenerative sequelae. The candidate will work with mouse models of stroke and TBI, specifically the murine middle cerebral artery occlusion model. Other responsibilities include high‑resolution and confocal microscopy, cellular and molecular immune profiling, therapeutic drug evaluation, and detailed assessments of motor and cognitive functions. The laboratory also develops novel transgenic animals and is involved in commercialization of therapeutic approaches.
Duties & Responsibilities
Participate in surgical procedures related to the described projects.
Prepare brain sections from mice and process them for histology and immune microscopy.
Perform various microscopy techniques including high‑resolution and confocal imaging.
Evaluate mice via behavioral tasks to assess motor and cognitive functions.
Conduct high‑dimensional analyses of the post‑injury immune landscape and interpret data.
Use image‑analysis software to generate and analyze images.
Determine behavioral outcomes in relation to pathophysiological findings.
Collaborate with other lab personnel on related projects.
Participate in lab meetings and project‑specific meetings with other lab personnel.
Maintain laboratory notebooks, archives, and records.
Assist with writing manuscripts and grant proposals.
Stay current with relevant literature.
Minimum Experience and Training Requirements A PhD in biology or a related natural, life or health‑care science is required. Candidates with prior experience in the murine middle cerebral artery occlusion model may be considered with a Bachelor’s degree.
Physical Requirements Ability to perform job functions in an upright position. Ability to perform job functions while seated. Ability to walk or move. Ability to climb stairs. Ability to work indoors and in cold temperature extremes. Ability to bend, twist at the waist, and perform repetitive hand movements. Ability to lift and carry up to 15 lbs. Ability to maintain vision and hearing acuity. Ability to work rotating shifts, overtime, and new processes as required.
Equal Opportunity Employer Statement The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. MUSC participates in the federal E‑Verify program to confirm the identity and employment authorization of newly hired employees.
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Job Description Summary Seeking an individual, preferably with microsurgical experience, for a position in neuroimmunology that encompasses basic and translational research. Work will focus on the complement system and neuroinflammatory mechanisms. Projects involve investigating acute and chronic neuroimmune responses after stroke or traumatic brain injury, including long‑term neurodegenerative sequelae. The candidate will work with mouse models of stroke and TBI, specifically the murine middle cerebral artery occlusion model. Other responsibilities include high‑resolution and confocal microscopy, cellular and molecular immune profiling, therapeutic drug evaluation, and detailed assessments of motor and cognitive functions. The laboratory also develops novel transgenic animals and is involved in commercialization of therapeutic approaches.
Duties & Responsibilities
Participate in surgical procedures related to the described projects.
Prepare brain sections from mice and process them for histology and immune microscopy.
Perform various microscopy techniques including high‑resolution and confocal imaging.
Evaluate mice via behavioral tasks to assess motor and cognitive functions.
Conduct high‑dimensional analyses of the post‑injury immune landscape and interpret data.
Use image‑analysis software to generate and analyze images.
Determine behavioral outcomes in relation to pathophysiological findings.
Collaborate with other lab personnel on related projects.
Participate in lab meetings and project‑specific meetings with other lab personnel.
Maintain laboratory notebooks, archives, and records.
Assist with writing manuscripts and grant proposals.
Stay current with relevant literature.
Minimum Experience and Training Requirements A PhD in biology or a related natural, life or health‑care science is required. Candidates with prior experience in the murine middle cerebral artery occlusion model may be considered with a Bachelor’s degree.
Physical Requirements Ability to perform job functions in an upright position. Ability to perform job functions while seated. Ability to walk or move. Ability to climb stairs. Ability to work indoors and in cold temperature extremes. Ability to bend, twist at the waist, and perform repetitive hand movements. Ability to lift and carry up to 15 lbs. Ability to maintain vision and hearing acuity. Ability to work rotating shifts, overtime, and new processes as required.
Equal Opportunity Employer Statement The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. MUSC participates in the federal E‑Verify program to confirm the identity and employment authorization of newly hired employees.
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