Revolution Medicines
Senior Director, Cancer Immunology
Revolution Medicines, San Francisco, California, United States, 94199
Revolution Medicines is a clinical‑stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS‑addicted cancers. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
Opportunity This role represents a unique opportunity to serve as a strategic and scientific leader within Cancer Immunology, reporting into the Biology organization. We are seeking a highly motivated, critical thinker with a passion for scientific excellence and innovation, who can drive the discovery and advancement of novel immuno‑oncology targets and modalities. The successful candidate will lead a multidisciplinary team, shape the scientific vision for Discovery Cancer Immunology, and provide oversight of scientific integration across both Discovery and Translational Cancer Immunology.
Key Responsibilities
Discovery Program Leadership & Strategic Oversight: lead Cancer Immunology discovery programs from project qualification through Development Candidate nomination, drive identification and validation of novel immuno‑oncology targets, ensuring seamless progression into Translational Cancer Immunology.
Platform & Modality Innovation: oversee development and optimization of experimental platforms, including in vitro and in vivo models, phenotypic screening, and advanced assay toolkits; champion new therapeutic modalities such as TCEs, ADCs, and bispecifics.
Scientific Integration & Operational Excellence: provide strategic oversight of scientific integration across Discovery and Translational Cancer Immunology, ensuring operational rigor, platform support, and alignment of resources; promote deployment of modern data systems and analytics to advance scientific and operational excellence.
Cross‑functional Collaboration: partner with Research Leadership to support advancement of programs from early discovery into the clinical development portfolio; coordinate discovery efforts, platform capabilities, and translational priorities.
Team Leadership & Mentorship: lead, mentor, and inspire a multidisciplinary team of PhD and non‑PhD scientists; cultivate a culture of scientific excellence, innovation, and collaboration.
External Engagement: spearhead collaborations with academic partners and external organizations, define publication strategies, and support the company’s scientific reputation.
Required Skills, Experience, and Education
Ph.D. in immunology, cancer biology, or related discipline; deep expertise in tumor immunology, immune‑evasive oncogenic signaling pathways, and/or immunotherapy; proven track record of excellence in research with high‑impact publications.
Industry experience in oncology drug discovery and development, including antibody‑directed therapies such as T cell engagers, ADCs, or bispecific antibodies; early discovery strategy experience desirable.
Demonstrated leadership and people‑management skills; experience leading multidisciplinary teams and mentoring scientists.
Strategic and analytical thinker capable of prioritizing initiatives, anticipating challenges, and executing effectively in a dynamic, high‑energy environment; rigorous, quantitative, detail‑oriented experimentalist.
Excellent written and verbal communication skills; ability to influence and align diverse stakeholders; thrives in collaborative, interdisciplinary teams.
Preferred Skills
Experience with chemistry‑based therapies, including small molecules or ADC payloads.
Familiarity with bioinformatics‑driven discovery and integrating computational insights into experimental design.
Proficiency with modern data platforms, machine learning approaches, and advanced analytics for Cancer Immunology research and decision‑making.
Prior experience as a Program Team Leader, driving cross‑functional strategy and execution across discovery and development stages.
Compensation & Benefits Base pay salary range for this full‑time position, onsite at our headquarters in Redwood City, CA:
$236,000 — $295,000 USD
Base pay is one part of our overall total rewards program, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Position Details Seniority level: Director Employment type: Full‑time
Equal Opportunity Employment Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Privacy Statement Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
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Opportunity This role represents a unique opportunity to serve as a strategic and scientific leader within Cancer Immunology, reporting into the Biology organization. We are seeking a highly motivated, critical thinker with a passion for scientific excellence and innovation, who can drive the discovery and advancement of novel immuno‑oncology targets and modalities. The successful candidate will lead a multidisciplinary team, shape the scientific vision for Discovery Cancer Immunology, and provide oversight of scientific integration across both Discovery and Translational Cancer Immunology.
Key Responsibilities
Discovery Program Leadership & Strategic Oversight: lead Cancer Immunology discovery programs from project qualification through Development Candidate nomination, drive identification and validation of novel immuno‑oncology targets, ensuring seamless progression into Translational Cancer Immunology.
Platform & Modality Innovation: oversee development and optimization of experimental platforms, including in vitro and in vivo models, phenotypic screening, and advanced assay toolkits; champion new therapeutic modalities such as TCEs, ADCs, and bispecifics.
Scientific Integration & Operational Excellence: provide strategic oversight of scientific integration across Discovery and Translational Cancer Immunology, ensuring operational rigor, platform support, and alignment of resources; promote deployment of modern data systems and analytics to advance scientific and operational excellence.
Cross‑functional Collaboration: partner with Research Leadership to support advancement of programs from early discovery into the clinical development portfolio; coordinate discovery efforts, platform capabilities, and translational priorities.
Team Leadership & Mentorship: lead, mentor, and inspire a multidisciplinary team of PhD and non‑PhD scientists; cultivate a culture of scientific excellence, innovation, and collaboration.
External Engagement: spearhead collaborations with academic partners and external organizations, define publication strategies, and support the company’s scientific reputation.
Required Skills, Experience, and Education
Ph.D. in immunology, cancer biology, or related discipline; deep expertise in tumor immunology, immune‑evasive oncogenic signaling pathways, and/or immunotherapy; proven track record of excellence in research with high‑impact publications.
Industry experience in oncology drug discovery and development, including antibody‑directed therapies such as T cell engagers, ADCs, or bispecific antibodies; early discovery strategy experience desirable.
Demonstrated leadership and people‑management skills; experience leading multidisciplinary teams and mentoring scientists.
Strategic and analytical thinker capable of prioritizing initiatives, anticipating challenges, and executing effectively in a dynamic, high‑energy environment; rigorous, quantitative, detail‑oriented experimentalist.
Excellent written and verbal communication skills; ability to influence and align diverse stakeholders; thrives in collaborative, interdisciplinary teams.
Preferred Skills
Experience with chemistry‑based therapies, including small molecules or ADC payloads.
Familiarity with bioinformatics‑driven discovery and integrating computational insights into experimental design.
Proficiency with modern data platforms, machine learning approaches, and advanced analytics for Cancer Immunology research and decision‑making.
Prior experience as a Program Team Leader, driving cross‑functional strategy and execution across discovery and development stages.
Compensation & Benefits Base pay salary range for this full‑time position, onsite at our headquarters in Redwood City, CA:
$236,000 — $295,000 USD
Base pay is one part of our overall total rewards program, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Position Details Seniority level: Director Employment type: Full‑time
Equal Opportunity Employment Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Privacy Statement Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
#J-18808-Ljbffr