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TALENT Software Services

Research Associate II

TALENT Software Services, South San Francisco, California, us, 94083

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The Antibody Engineering Department leverages state-of-the-art approaches and technologies to client and engineer antibody-based therapies to improve patient well-being. We are seeking a highly motivated and talented individual to join our dynamic and fast‑paced environment to support this mission. The primary focus of this hands‑on laboratory position will be to implement and apply molecular biology and biochemistry techniques, namely phage display, to support the antibody discovery process. The successful candidate will work closely with Antibody Engineering scientists to deploy the above approaches to help client antibodies for application across broad, multi‑functional efforts geared towards therapeutic development.

Qualifications and Experience

B.S./B.A. degree or higher in biology, chemistry, or a related field

5‑10 years of relevant industrial experience, ideally in a drug discovery setting

Basic biochemistry and/or molecular biology laboratory skills, including:

RNA isolation

Bacterial culture

Phage display – PCR and ELISA (not required, but would set a candidate apart; this is the primary function of this role, but RRP is willing to train the right candidate)

Molecular cloning and DNA/protein sequence analysis

Experience with Microsoft Excel and Microsoft PowerPoint

Excellent record‑keeping and communication skills

Excitement and enthusiasm to work in a dynamic, collaborative, and fast‑paced environment

Experience measuring protein‑protein interaction binding affinity using surface plasmon resonance is a plus

Key Responsibilities

Generate antibody phage display libraries and perform in‑vitro selections to identify candidate binding clones

Interface with colleagues within Antibody Engineering to understand and address program needs to inform selection strategies

Use high‑throughput biochemical techniques (e.g., ELISA, surface plasmon resonance) to rigorously characterize antibody candidates

Deploy molecular biology approaches (e.g., PCR, cloning) to enable rapid recombinant expression of candidate clones

Maintain and share detailed records of results for facile transfer of binding clones to program teams for further characterization

Job Location: South San Francisco, CA (Building 42) – Onsite position

Interview Process:

Phone screening

In‑person or virtual interview

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