Madrigal Pharmaceuticals
Senior Director, Clinical Practice Liaisons
Madrigal Pharmaceuticals, Los Angeles, California, United States, 90079
Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a liver disease with high unmet medical need. Madrigal’s medication Rezdiffra (resmetirom) is a once-daily oral liver‑directed THR‑β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).
Position Title Sr. Director Clinical Practice Liaison (CPL)
Role Overview This key field‑based leadership position is responsible for the strategic and tactical oversight of the CPL team within a defined U.S. region. The Sr. Director will manage and develop CPLs, ensuring the team executes against the company’s medical strategy, complies with regulatory and internal policies, and delivers scientific value to both internal and external stakeholders.
Key Responsibilities
Recruit, coach and manage performance of regional CPLs.
Foster continuous development through mentoring and training.
Align CPL activities with strategic objectives and tactical plans.
Drive implementation of regional field medical strategies and translate national objectives into actionable, regionally tailored activities.
Partner with cross‑functional teams to integrate field insights into medical planning.
Collaborate closely with Sales, Marketing, Market Access and Clinical Operations.
Serve as a field‑based liaison for HQ Medical Affairs initiatives and contribute to launch readiness and lifecycle management strategies.
Collaborate with Clinical Operations to ensure successful study execution.
Represent Medical Affairs at U.S. medical congresses in a compliant manner.
Coordinate booth planning, scientific exchange, competitive intelligence and post‑conference debriefs.
Contribute to the design and structure of the U.S. Field Medical team and identify evolving business needs to adjust regional capabilities accordingly.
Ensure all CPL activities comply with company SOPs, industry standards and applicable regulations.
Uphold the highest ethical standards in all external engagements.
Willingness to travel 25‑75% for congresses, site visits and stakeholder engagement.
Qualifications & Experience
Advanced degree in a scientific or healthcare discipline (MD, PharmD, PhD, DNP, etc.).
Minimum 5 years of Medical Affairs experience, including at least 3 years as an MSL or equivalent.
Minimum 3 years of people management experience or formal leadership development participation.
In‑depth knowledge of clinical medicine and medical research; experience in cardiometabolic health or MASH/NASH preferred.
Proven ability to understand, communicate and translate complex scientific information.
Strong knowledge of the U.S. healthcare system, FDA regulations and medical affairs compliance standards.
Demonstrated cross‑functional collaboration, project execution and strategic planning skills.
Proficiency in Microsoft Office Suite, virtual communication platforms (e.g. Zoom) and CRM systems (e.g. Veeva).
Strong interpersonal, presentation and relationship‑building skills.
Adaptable and proactive in a fast‑paced evolving environment.
Passion for mentoring, team building and field‑based medical innovation.
Compensation & Benefits Base salary range $262,000–$320,000 per year. Equity in the company is offered as part of the total rewards strategy. Comprehensive benefits include medical, dental, vision, life and disability insurance, 401(k) with Roth and employer match, flexible paid time off, supplemental mental health benefits through the Employee Assistance Program, and other benefits in accordance with applicable federal, state and local laws.
EEO Statement & Accommodations Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status or other characteristics protected by applicable law.
We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact
Human Resources
via the Madrigal Careers site.
Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.
#J-18808-Ljbffr
Position Title Sr. Director Clinical Practice Liaison (CPL)
Role Overview This key field‑based leadership position is responsible for the strategic and tactical oversight of the CPL team within a defined U.S. region. The Sr. Director will manage and develop CPLs, ensuring the team executes against the company’s medical strategy, complies with regulatory and internal policies, and delivers scientific value to both internal and external stakeholders.
Key Responsibilities
Recruit, coach and manage performance of regional CPLs.
Foster continuous development through mentoring and training.
Align CPL activities with strategic objectives and tactical plans.
Drive implementation of regional field medical strategies and translate national objectives into actionable, regionally tailored activities.
Partner with cross‑functional teams to integrate field insights into medical planning.
Collaborate closely with Sales, Marketing, Market Access and Clinical Operations.
Serve as a field‑based liaison for HQ Medical Affairs initiatives and contribute to launch readiness and lifecycle management strategies.
Collaborate with Clinical Operations to ensure successful study execution.
Represent Medical Affairs at U.S. medical congresses in a compliant manner.
Coordinate booth planning, scientific exchange, competitive intelligence and post‑conference debriefs.
Contribute to the design and structure of the U.S. Field Medical team and identify evolving business needs to adjust regional capabilities accordingly.
Ensure all CPL activities comply with company SOPs, industry standards and applicable regulations.
Uphold the highest ethical standards in all external engagements.
Willingness to travel 25‑75% for congresses, site visits and stakeholder engagement.
Qualifications & Experience
Advanced degree in a scientific or healthcare discipline (MD, PharmD, PhD, DNP, etc.).
Minimum 5 years of Medical Affairs experience, including at least 3 years as an MSL or equivalent.
Minimum 3 years of people management experience or formal leadership development participation.
In‑depth knowledge of clinical medicine and medical research; experience in cardiometabolic health or MASH/NASH preferred.
Proven ability to understand, communicate and translate complex scientific information.
Strong knowledge of the U.S. healthcare system, FDA regulations and medical affairs compliance standards.
Demonstrated cross‑functional collaboration, project execution and strategic planning skills.
Proficiency in Microsoft Office Suite, virtual communication platforms (e.g. Zoom) and CRM systems (e.g. Veeva).
Strong interpersonal, presentation and relationship‑building skills.
Adaptable and proactive in a fast‑paced evolving environment.
Passion for mentoring, team building and field‑based medical innovation.
Compensation & Benefits Base salary range $262,000–$320,000 per year. Equity in the company is offered as part of the total rewards strategy. Comprehensive benefits include medical, dental, vision, life and disability insurance, 401(k) with Roth and employer match, flexible paid time off, supplemental mental health benefits through the Employee Assistance Program, and other benefits in accordance with applicable federal, state and local laws.
EEO Statement & Accommodations Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status or other characteristics protected by applicable law.
We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact
Human Resources
via the Madrigal Careers site.
Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.
#J-18808-Ljbffr