The University of North Carolina
MATRIX Post-Doc Research Associate
The University of North Carolina, Chapel Hill, North Carolina, United States, 27517
MATRIX Post-Doc Research Associate
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The University of North Carolina at Chapel Hill
Posting Information
Department: Renaissance Computing Institute – 637100
Posting Open Date: 07/29/2025
Application Deadline: Open Until Filled – Yes
Position Type: Postdoctoral Scholar
Position Title: MATRIX Post-Doc Research Associate
Vacancy ID: PDS004609
Full-time/Part-time: Full-Time Temporary
Hours per week: 40
FTE: 1
Work Location: Chapel Hill, NC (Virginia, US)
Proposed Start Date: 09/01/2025
Estimated Duration of Appointment: 12 Months
Position Summary The Renaissance Computing Institute (RENCI) at UNC Chapel Hill is seeking a MATRIX Postdoctoral Research Associate to join our interdisciplinary team at the forefront of biomedical data integration and AI-driven discovery. In this role, you will design and implement sophisticated data ingestion and transformation workflows that unify diverse biomedical sources into structured, queryable knowledge graphs. Your work will support the creation of FAIR-aligned metadata (including emerging standards like Croissant) to ensure data provenance, accessibility, and reuse across translational science domains. You will shape infrastructure that enables expressive querying (e.g., via the Model Context Protocol) and optimize integrated data for downstream AI/ML applications such as predictive modeling and pathfinding. This includes exploring the use of large language models (LLMs) for schema mapping and normalization tasks, evaluating embedding strategies that enhance interpretability, and developing novel approaches that use AI and knowledge graphs to make novel predictions and answer complex user queries. The ideal candidate is enthusiastic about contributing to open-source tools, co-authoring publications, and presenting research at national and international venues.
Minimum Education And Experience Requirements Ph.D. in Bioinformatics, Biomedical Informatics, Computer Science, or a related field.
Preferred Qualifications, Competencies, And Experience
Experience with Knowledge Graph machine learning including KG embeddings.
Strong background in data integration, ETL pipeline design, and schema transformation.
Familiarity with workflow managers, with a preference for experience using tools like Kedro, Airflow, Snakemake, or similar.
Understanding of semantic modeling and ontology use (e.g., Biolink, RDF/OWL, OBO ontologies).
Proficiency in Python and collaborative software development workflows.
Familiarity with version control and team-based development using Git.
Equal Opportunity Employer Statement The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.
Posting Contact Information Department Contact Name and Title: Misty Parrish, Human Resources Specialist Department Contact Email: misty.parrish@unc.edu
Postdoctoral Affairs Contact Information If you experience any problems accessing the system or have questions about the application process, please contact the University’s Office of Postdoctoral Affairs at (919) 962-9982 or send an email to opahr@unc.edu. Please note: The Office of Postdoctoral Affairs will not be able to provide specific updates regarding position or application status.
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at
The University of North Carolina at Chapel Hill
Posting Information
Department: Renaissance Computing Institute – 637100
Posting Open Date: 07/29/2025
Application Deadline: Open Until Filled – Yes
Position Type: Postdoctoral Scholar
Position Title: MATRIX Post-Doc Research Associate
Vacancy ID: PDS004609
Full-time/Part-time: Full-Time Temporary
Hours per week: 40
FTE: 1
Work Location: Chapel Hill, NC (Virginia, US)
Proposed Start Date: 09/01/2025
Estimated Duration of Appointment: 12 Months
Position Summary The Renaissance Computing Institute (RENCI) at UNC Chapel Hill is seeking a MATRIX Postdoctoral Research Associate to join our interdisciplinary team at the forefront of biomedical data integration and AI-driven discovery. In this role, you will design and implement sophisticated data ingestion and transformation workflows that unify diverse biomedical sources into structured, queryable knowledge graphs. Your work will support the creation of FAIR-aligned metadata (including emerging standards like Croissant) to ensure data provenance, accessibility, and reuse across translational science domains. You will shape infrastructure that enables expressive querying (e.g., via the Model Context Protocol) and optimize integrated data for downstream AI/ML applications such as predictive modeling and pathfinding. This includes exploring the use of large language models (LLMs) for schema mapping and normalization tasks, evaluating embedding strategies that enhance interpretability, and developing novel approaches that use AI and knowledge graphs to make novel predictions and answer complex user queries. The ideal candidate is enthusiastic about contributing to open-source tools, co-authoring publications, and presenting research at national and international venues.
Minimum Education And Experience Requirements Ph.D. in Bioinformatics, Biomedical Informatics, Computer Science, or a related field.
Preferred Qualifications, Competencies, And Experience
Experience with Knowledge Graph machine learning including KG embeddings.
Strong background in data integration, ETL pipeline design, and schema transformation.
Familiarity with workflow managers, with a preference for experience using tools like Kedro, Airflow, Snakemake, or similar.
Understanding of semantic modeling and ontology use (e.g., Biolink, RDF/OWL, OBO ontologies).
Proficiency in Python and collaborative software development workflows.
Familiarity with version control and team-based development using Git.
Equal Opportunity Employer Statement The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.
Posting Contact Information Department Contact Name and Title: Misty Parrish, Human Resources Specialist Department Contact Email: misty.parrish@unc.edu
Postdoctoral Affairs Contact Information If you experience any problems accessing the system or have questions about the application process, please contact the University’s Office of Postdoctoral Affairs at (919) 962-9982 or send an email to opahr@unc.edu. Please note: The Office of Postdoctoral Affairs will not be able to provide specific updates regarding position or application status.
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