Vivatides Therapeutics Inc.
Associate Director/Director/Sr. Director, Oligonucleotide Chemistry, Woburn
Vivatides Therapeutics Inc., Woburn, Massachusetts, us, 01813
As an exciting start‑up, we offer an amazing opportunity to develop the next generation RNA therapeutics. We are seeking a well‑organized and self‑motivated senior scientist to join our company site in Woburn, MA. The successful candidate will be a key member of the drug discovery group and will lead efforts to advance siRNA/ASO therapeutics to treat intractable diseases. Strong knowledge of oligonucleotide drug design and experience in organic chemistry of oligonucleotide precursors, respective delivery vehicles and methods is a must. Experience in oligonucleotide post‑conjugation methods is a strong plus. Experience of work with oligo synthesizers is a plus but not required. Proven track record of leadership of successful projects in oligonucleotide drug discovery and strong publication record of scientific papers and patents.
Primary Responsibilities:
Chemistry platform design and refining.
CMC planning.
Direct chemistry informatics (internal databases, literature and patent search).
Drafting of patent applications.
Oversee team performance.
Manage FFS/FTE projects with CROs.
Follow and further refine company standards of data collection, presentation, and QC.
May need to establish new specialized chemistry units, screen/recruit candidate chemists.
Qualifications:
Ph.D. in Organic or Medicinal Chemistry.
Minimum of 5 years of experience in oligonucleotide drug discovery, with at least 2 years in a leadership role.
Deep understanding of oligonucleotide and precursor synthesis, modification, purification, and conjugation mechanisms.
Familiarity with analytical methods and quality standards in oligonucleotide drug development.
Strong project management skills and cross‑functional communication abilities.
Seniority level Director
Employment type Full‑time
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Primary Responsibilities:
Chemistry platform design and refining.
CMC planning.
Direct chemistry informatics (internal databases, literature and patent search).
Drafting of patent applications.
Oversee team performance.
Manage FFS/FTE projects with CROs.
Follow and further refine company standards of data collection, presentation, and QC.
May need to establish new specialized chemistry units, screen/recruit candidate chemists.
Qualifications:
Ph.D. in Organic or Medicinal Chemistry.
Minimum of 5 years of experience in oligonucleotide drug discovery, with at least 2 years in a leadership role.
Deep understanding of oligonucleotide and precursor synthesis, modification, purification, and conjugation mechanisms.
Familiarity with analytical methods and quality standards in oligonucleotide drug development.
Strong project management skills and cross‑functional communication abilities.
Seniority level Director
Employment type Full‑time
Referrals increase your chances of interviewing at Vivatides Therapeutics Inc. by 2x
#J-18808-Ljbffr