Aditi Consulting
Principal Research Scientist
Aditi Consulting, Lexington, Massachusetts, United States, 02173
This range is provided by Aditi Consulting. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.
Base pay range $142.08/hr - $142.08/hr
Summary The Sr. Scientist will act as a DMPK project representative and provide scientific leadership in the discovery of small molecule drug candidates by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas. This will be achieved by proposing and leading internal and external research efforts to support project goals. The Sr. Scientist will work closely with pharmacology and medicinal chemistry teams, lead DMPK efforts to optimize molecules across a variety of therapeutic areas utilizing in vitro, in vivo, and in silico methods and models to generate client chemical matter with drug‑like properties. The Sr. Scientist will collaborate with outsourcing managers to identify and manage CROs with specialized ADME capabilities, and build and maintain relationships with global ADME experts to leverage expertise and harmonize ADME strategy. The individual will be seen across the company and begin to be viewed externally as a method/subject expert within small molecule DMPK.
Responsibilities
Function as DMPK project representative for global, cross‑functional small molecule project teams to achieve project goals
Provide expert‑level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
Troubleshoot highly complex tasks through independent and team‑based efforts
Demonstrate deep subject matter expertise and in‑depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
Make independent decisions related to day‑to‑day experimental activities
Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
Analyze complex data with high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
Ensure proper documentation of all experiments and data
Collaborative teamwork
Communicate regularly with international colleagues within Company
Actively participate in cross‑functional teams and meetings to drive project success
Achieve business goals, share learnings, knowledge and skills & promote cross‑functional teamwork
Share knowledge & expertise to expand team capabilities and goals
Demonstrate superior cross‑cultural understanding to effectively interact with relevant stakeholders in the global organization
Write and review collaborative research manuscripts, project documents, and milestone documents
Complete assignments requiring expert‑level knowledge of techniques and practices related to the research area
Represent the organization as subject matter expert by attending and presenting at scientific conferences and global meetings
Qualifications
Bachelor's Degree within subject matter expertise required.
18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree in with 6+ years’ post‑doctoral and/or industry relevant experience can be considered.
Relevant required experience includes: Excellent understanding of ADME principals with knowledge of PK/PD modeling or biotransformation highly desirable
Preferred experience includes: Prior experience working in a fully or hybrid ADME‑outsourced models
Demonstrates excellent verbal and written communication skills.
Pay Transparency The typical base pay for this role across the U.S. is $142.08 - $142.08/hour. Non‑exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law. Full‑time employees are eligible to select from different benefits packages. Packages may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law.
Seniority level Entry level
Employment type Contract
Job function Other
Industries Pharmaceutical Manufacturing
Referrals increase your chances of interviewing at Aditi Consulting by 2x
#J-18808-Ljbffr
Base pay range $142.08/hr - $142.08/hr
Summary The Sr. Scientist will act as a DMPK project representative and provide scientific leadership in the discovery of small molecule drug candidates by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas. This will be achieved by proposing and leading internal and external research efforts to support project goals. The Sr. Scientist will work closely with pharmacology and medicinal chemistry teams, lead DMPK efforts to optimize molecules across a variety of therapeutic areas utilizing in vitro, in vivo, and in silico methods and models to generate client chemical matter with drug‑like properties. The Sr. Scientist will collaborate with outsourcing managers to identify and manage CROs with specialized ADME capabilities, and build and maintain relationships with global ADME experts to leverage expertise and harmonize ADME strategy. The individual will be seen across the company and begin to be viewed externally as a method/subject expert within small molecule DMPK.
Responsibilities
Function as DMPK project representative for global, cross‑functional small molecule project teams to achieve project goals
Provide expert‑level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
Troubleshoot highly complex tasks through independent and team‑based efforts
Demonstrate deep subject matter expertise and in‑depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
Make independent decisions related to day‑to‑day experimental activities
Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
Analyze complex data with high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
Ensure proper documentation of all experiments and data
Collaborative teamwork
Communicate regularly with international colleagues within Company
Actively participate in cross‑functional teams and meetings to drive project success
Achieve business goals, share learnings, knowledge and skills & promote cross‑functional teamwork
Share knowledge & expertise to expand team capabilities and goals
Demonstrate superior cross‑cultural understanding to effectively interact with relevant stakeholders in the global organization
Write and review collaborative research manuscripts, project documents, and milestone documents
Complete assignments requiring expert‑level knowledge of techniques and practices related to the research area
Represent the organization as subject matter expert by attending and presenting at scientific conferences and global meetings
Qualifications
Bachelor's Degree within subject matter expertise required.
18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree in with 6+ years’ post‑doctoral and/or industry relevant experience can be considered.
Relevant required experience includes: Excellent understanding of ADME principals with knowledge of PK/PD modeling or biotransformation highly desirable
Preferred experience includes: Prior experience working in a fully or hybrid ADME‑outsourced models
Demonstrates excellent verbal and written communication skills.
Pay Transparency The typical base pay for this role across the U.S. is $142.08 - $142.08/hour. Non‑exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law. Full‑time employees are eligible to select from different benefits packages. Packages may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law.
Seniority level Entry level
Employment type Contract
Job function Other
Industries Pharmaceutical Manufacturing
Referrals increase your chances of interviewing at Aditi Consulting by 2x
#J-18808-Ljbffr