BioSpace
Senior Scientist Research Computational Biology (ARIA)
BioSpace, Washington, District of Columbia, us, 20022
Senior Scientist, Research Computational Biology (ARIA)
Join Amgen’s mission to serve patients living with serious illnesses. The ARIA Computational Biology team seeks a talented and creative computational biologist to accelerate the identification, prioritization, and validation of transformative therapeutic targets in a dynamic cross‑functional research environment.
Focus Areas
Extracting biological insight from complex multi‑modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses.
Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities.
Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships.
Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms.
Qualifications Basic Qualifications
Doctorate in computational biology, bioinformatics, data science, or a related discipline plus relevant post‑doctoral experience.
Or Master’s degree and 3 years of relevant research experience.
Or bachelor’s degree and 5 years of relevant research experience.
Preferred Qualifications
Strong programming skills (Python, R, Linux/Unix); familiarity with cloud computing, HPC, and collaborative coding practices (e.g., Git).
Track record of designing and implementing creative and holistic computational strategies to address challenging research questions.
Demonstrated expertise in the analysis and interpretation of single‑cell omics data.
Excellent presentation and communication skills to convey complex findings to diverse audiences.
Self‑starter with a collaborative mentality and a drive for continuous growth.
Strong background in cardiometabolic disease and/or immunology, including application to the interpretation of single‑cell data.
Experience leveraging and fine‑tuning transcriptional foundation models, LLMs, and biomedical knowledge graphs to further research goals.
Familiarity with public data resources (e.g., DepMap, Human Cell Atlas, TCGA, GTEx, Tahoe‑100M) frequently used to augment analyses of internally generated data.
Experience developing and deploying tools and pipelines to endpoints such as interactive portals (e.g., RShiny apps), workflow management systems (e.g., Nextflow), and agentic frameworks.
What you can expect from us Amgen offers a comprehensive benefits package, a total rewards plan, and opportunities for professional growth, including remote and hybrid work arrangements where possible.
Benefits include
A comprehensive employee benefits package, including a retirement and savings plan with generous company contributions, group medical, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
Stock‑based long‑term incentives.
Award‑winning time‑off plans.
Flexible work models, including remote and hybrid work arrangements.
Salary Expected annual salary range (U.S.) is posted. Actual salary will vary based on factors including relevant skills, experience, and qualifications.
Equal Opportunity Employer Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will provide reasonable accommodation for individuals with disabilities.
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Focus Areas
Extracting biological insight from complex multi‑modal omics and screening data to characterize disease endotypes and mechanisms, identify novel targets and biomarkers, and test therapeutic hypotheses.
Developing and leveraging methods/platforms to discover, prioritize, and validate targets across diverse diseases and therapeutic modalities.
Innovative research in close partnership with Amgen therapeutic area scientists, spanning both internal pipeline programs and external partnerships.
Partnering with our data science and information systems teams to incorporate tools and analyses developed within ARIA Computational Biology into integrated R&D platforms.
Qualifications Basic Qualifications
Doctorate in computational biology, bioinformatics, data science, or a related discipline plus relevant post‑doctoral experience.
Or Master’s degree and 3 years of relevant research experience.
Or bachelor’s degree and 5 years of relevant research experience.
Preferred Qualifications
Strong programming skills (Python, R, Linux/Unix); familiarity with cloud computing, HPC, and collaborative coding practices (e.g., Git).
Track record of designing and implementing creative and holistic computational strategies to address challenging research questions.
Demonstrated expertise in the analysis and interpretation of single‑cell omics data.
Excellent presentation and communication skills to convey complex findings to diverse audiences.
Self‑starter with a collaborative mentality and a drive for continuous growth.
Strong background in cardiometabolic disease and/or immunology, including application to the interpretation of single‑cell data.
Experience leveraging and fine‑tuning transcriptional foundation models, LLMs, and biomedical knowledge graphs to further research goals.
Familiarity with public data resources (e.g., DepMap, Human Cell Atlas, TCGA, GTEx, Tahoe‑100M) frequently used to augment analyses of internally generated data.
Experience developing and deploying tools and pipelines to endpoints such as interactive portals (e.g., RShiny apps), workflow management systems (e.g., Nextflow), and agentic frameworks.
What you can expect from us Amgen offers a comprehensive benefits package, a total rewards plan, and opportunities for professional growth, including remote and hybrid work arrangements where possible.
Benefits include
A comprehensive employee benefits package, including a retirement and savings plan with generous company contributions, group medical, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
Stock‑based long‑term incentives.
Award‑winning time‑off plans.
Flexible work models, including remote and hybrid work arrangements.
Salary Expected annual salary range (U.S.) is posted. Actual salary will vary based on factors including relevant skills, experience, and qualifications.
Equal Opportunity Employer Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will provide reasonable accommodation for individuals with disabilities.
#J-18808-Ljbffr