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Sr Principal Scientist Target Discovery & Biology - Thousand Oaks, CA
VetJobs, Thousand Oaks, California, United States, 91362
Sr Principal Scientist Target Discovery & Biology - Thousand Oaks, CA
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Sr Principal Scientist Target Discovery & Biology - Thousand Oaks, CA
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Job Description
ATTENTION MILITARY AFFILIATED JOB SEEKERS – Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On‑Site" at the location detailed in the job post.
Let’s do this. Let’s change the world. Amgen’s Target Discovery & Biology (TD&B) organization integrates functional genomics screening, multi‑omics profiling, human genetics, and complex in vitro systems to uncover new biological insights and therapeutic targets. TD&B partners closely across Amgen’s therapeutic areas to translate data into discovery, accelerating the path to target discovery and prosecution.
Role We are seeking a highly motivated, innovative, and experienced Senior Principal Scientist based in Thousand Oaks to lead a team focused on the development, delivery, and implementation of complex in vitro models that help power target discovery and functional genomics efforts. In this essential role for discovery at Amgen, you will be part of a dynamic, cross‑functional team to advance target and biological discovery across Amgen’s therapeutic areas. In this vital role you will:
Provide scientific and operational leadership for a team of scientists delivering advanced in vitro models and screening‑ready systems in collaboration with therapeutic area partners.
Guide the design, optimization, and screen implementation of cellular models that capture disease‑relevant biology, integrating insights from disease tissue profiling data.
Champion partnerships with automation colleagues to accelerate model deployment and reproducibility.
Collaborate with Amgen therapeutic area scientists to define requirements, ensure biological relevance, and deliver systems that enable mechanistic and translational insights.
Identify and implement emerging technologies in cell engineering, automation, and complex model systems to enhance the sophistication and throughput of discovery platforms.
Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgen’s pipeline.
Auto req ID: 462073BR
Minimum Education Required: Bachelors
Job Category: Scientific Research & Development
Minimum Education Bachelors
Additional Qualifications & Responsibilities What we expect of you
The dynamic professional we seek is a leader with these qualifications.
Basic Qualifications
Doctorate degree (PhD, PharmD, or MD) AND relevant post‑doc where applicable AND 3 years of directly related experience.
OR Master’s degree AND 6 years of directly related experience.
OR Bachelor’s degree AND 8 years of directly related experience.
Preferred Qualifications
Doctorate degree in cell biology, molecular biology, biomedical engineering, or related discipline.
6+ years of relevant experience in biotech or pharma, including leadership of scientific teams.
Strong track record in complex in vitro model development, cell engineering, and high‑throughput or automated screening.
Experience with high‑content imaging and transcriptional assay readouts.
Demonstrated ability to collaborate with cross‑functional teams to translate disease biology into experimental models.
Experience with viral vector systems (AAV, lentivirus, or related technologies) for gene delivery and perturbation.
Experience in leading or mentoring scientists, with proven success in project execution and team development.
Familiarity with data‑driven discovery approaches, including integration of genetic or multi‑omics insights.
Excellent organizational and communication skills, with the ability to drive cross‑site collaboration in a matrixed research environment.
What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Compensation & Benefits
Base salary
Amgen offers a total rewards plan comprising health and welfare plans for staff and eligible dependents, financial plans with retirement savings opportunities.
Work/life balance and career development opportunities.
Comprehensive employee benefits package including retirement and savings plan, group medical, dental, vision coverage, life and disability insurance, and flexible spending accounts.
Discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
Stock‑based long‑term incentives.
Award‑winning time‑off plans.
Flexible work models where possible.
Salary Range: $171,106.00 – $209,556.00
Location City: Thousand Oaks; State: California
Employment Type Full‑time
Job Function Research, Analyst, and Information Technology
Senior Level Director
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Sr Principal Scientist Target Discovery & Biology - Thousand Oaks, CA
role at
VetJobs
Job Description
ATTENTION MILITARY AFFILIATED JOB SEEKERS – Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers. If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On‑Site" at the location detailed in the job post.
Let’s do this. Let’s change the world. Amgen’s Target Discovery & Biology (TD&B) organization integrates functional genomics screening, multi‑omics profiling, human genetics, and complex in vitro systems to uncover new biological insights and therapeutic targets. TD&B partners closely across Amgen’s therapeutic areas to translate data into discovery, accelerating the path to target discovery and prosecution.
Role We are seeking a highly motivated, innovative, and experienced Senior Principal Scientist based in Thousand Oaks to lead a team focused on the development, delivery, and implementation of complex in vitro models that help power target discovery and functional genomics efforts. In this essential role for discovery at Amgen, you will be part of a dynamic, cross‑functional team to advance target and biological discovery across Amgen’s therapeutic areas. In this vital role you will:
Provide scientific and operational leadership for a team of scientists delivering advanced in vitro models and screening‑ready systems in collaboration with therapeutic area partners.
Guide the design, optimization, and screen implementation of cellular models that capture disease‑relevant biology, integrating insights from disease tissue profiling data.
Champion partnerships with automation colleagues to accelerate model deployment and reproducibility.
Collaborate with Amgen therapeutic area scientists to define requirements, ensure biological relevance, and deliver systems that enable mechanistic and translational insights.
Identify and implement emerging technologies in cell engineering, automation, and complex model systems to enhance the sophistication and throughput of discovery platforms.
Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgen’s pipeline.
Auto req ID: 462073BR
Minimum Education Required: Bachelors
Job Category: Scientific Research & Development
Minimum Education Bachelors
Additional Qualifications & Responsibilities What we expect of you
The dynamic professional we seek is a leader with these qualifications.
Basic Qualifications
Doctorate degree (PhD, PharmD, or MD) AND relevant post‑doc where applicable AND 3 years of directly related experience.
OR Master’s degree AND 6 years of directly related experience.
OR Bachelor’s degree AND 8 years of directly related experience.
Preferred Qualifications
Doctorate degree in cell biology, molecular biology, biomedical engineering, or related discipline.
6+ years of relevant experience in biotech or pharma, including leadership of scientific teams.
Strong track record in complex in vitro model development, cell engineering, and high‑throughput or automated screening.
Experience with high‑content imaging and transcriptional assay readouts.
Demonstrated ability to collaborate with cross‑functional teams to translate disease biology into experimental models.
Experience with viral vector systems (AAV, lentivirus, or related technologies) for gene delivery and perturbation.
Experience in leading or mentoring scientists, with proven success in project execution and team development.
Familiarity with data‑driven discovery approaches, including integration of genetic or multi‑omics insights.
Excellent organizational and communication skills, with the ability to drive cross‑site collaboration in a matrixed research environment.
What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Compensation & Benefits
Base salary
Amgen offers a total rewards plan comprising health and welfare plans for staff and eligible dependents, financial plans with retirement savings opportunities.
Work/life balance and career development opportunities.
Comprehensive employee benefits package including retirement and savings plan, group medical, dental, vision coverage, life and disability insurance, and flexible spending accounts.
Discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan.
Stock‑based long‑term incentives.
Award‑winning time‑off plans.
Flexible work models where possible.
Salary Range: $171,106.00 – $209,556.00
Location City: Thousand Oaks; State: California
Employment Type Full‑time
Job Function Research, Analyst, and Information Technology
Senior Level Director
#J-18808-Ljbffr